NCT02626429

Completed

Protein Requirements In Active Female Populations

University of Toronto Source

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Other study identifiers

Sponsor study identifier

IAAO-YF

Study Type

interventional

Actual enrollment (reported)

6

Locations

0 countries

Sites

N/A

Timeline

Study Start

May 2015

Actual (reported)

Primary Completion

June 2017

Actual (reported)

Study Completion

June 2017

Actual (reported)

Brief Summary

Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA). Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity. Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than the RDA based on nitrogen balance data. The purpose of this study is to measure the protein requirement in active, young adult females using the IAAO technique in the presence of a variable intensity exercise stimulus.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 6 participants
Study completion date: June 2017
Actual (reported)
Listed locations: 0 countries · 0 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
May 2015
Actual (reported)
First Submitted
December 7, 2015
Actual (reported)
First Posted
December 10, 2015
Actual (reported)
Primary Completion
June 2017
Actual (reported)
Study Completion
June 2017
Actual (reported)

Last Updated: December 11, 2017
Status Verified: December 2017
Last Update Submitted: December 7, 2017

Conditions

Healthy Increased Metabolic Requirement

Outcome Measures

Primary Outcomes (1)

13CO2 (carbon dioxide) excretion (μmol/kg/h)
4 hours / study day

Secondary Outcomes (1)

13C-Phenylalanine Oxidation (μmol/kg/h)
4 hours / study day

Study Arms (1)

Active, Young Adult Famale

EXPERIMENTAL

Participants will complete a bout of exercise and then consume a randomly assigned amino acid intake prior to measuring whole body 13CO2 excretion and phenylalanine oxidation.

Dietary Supplement: Amino acid intake

Interventions

Amino acid intakeDietary supplement

Amino acid intakes will be varied at 0.2-2.6 g/kg/day

Active, Young Adult Famale

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 35 Years

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Healthy, active, young adult females who regularly participate in moderate-vigorous activity 5x per week, for a minimum of 1 hour
A minimum score of 10 on the Beep Test (a measure of aerobic fitness)

Sponsors & Collaborators

Ajinomoto Co., Inc.
Industrycollaborator
University of Toronto
Otherlead

Enrollment

6 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: BASIC SCIENCE
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Assistant professaor

Study Record Dates

First Submitted

December 7, 2015

First Posted

December 10, 2015

Study Start

May 2015

Actual (reported)

NCT02859181

Protein Requirements for Active Adolescent Males (IAAO-AM)

Not ApplicableCompleted

NCT03696264

Protein Requirements in Resistance-trained Males

Not ApplicableCompleted

NCT02628249

Rate-limiting Amino Acids in Endurance-trained Athlete

Not ApplicableCompleted

NCT02874638

Effect of Non-essential Amino Acids on Protein Requirements for Endurance Athletes

Not ApplicableCompleted

NCT06431334

Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique

Not ApplicableCompleted

NCT02478801

Protein Requirements in Endurance-trained Athlete

Early Phase 1Completed

You may not qualify if:

Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
Regular tobacco use
Illicit drug use

Contact the study team to confirm eligibility.

Primary Completion

June 2017

Actual (reported)

Study Completion

June 2017

Actual (reported)

Last Updated

December 11, 2017

Record last verified: 2017-12

Source record

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Source: ClinicalTrials.gov.

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Registry identifier: NCT02626429
Data provider: ClinicalTrials.gov
Source updated: 2017-12-11
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:39:47 UTC

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

Active, Young Adult Famale

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record