NCT02478801|CompletedEarly Phase 1
Protein Requirements in Endurance-trained Athlete
EP
Evaluation of Protein Requirements in Male Endurance Athletes
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EP
Evaluation of Protein Requirements in Male Endurance Athletes
Sponsor study identifier
interventional
9
0 countries
N/A
Study Start
March 2015
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
January 2016
Actual (reported)Study Completion
May 2016
Actual (reported)Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA). Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity. Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than RDA based on nitrogen balance data. Therefore, the purpose of this study is to measure the protein requirement in endurance trained adults using the IAAO technique.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2016
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2015
Date type not reportedThis date has not been verified as actual or estimated.
June 18, 2015
Actual (reported)June 23, 2015
Actual (reported)January 2016
Actual (reported)May 2016
Actual (reported)13CO2 (carbon dioxide) excretion (μmol/kg/h)
4 hours / study day
[13C]phenylalanine oxidation (μmol/kg/h)
4 hours/study day
subjects will receive different levels of amino acids intakes varying from 0.2 to 2.8 g/kg/day.
amino acids intakes will be varied at 0.2-2.8 g/kg/day
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Kato H, Suzuki K, Bannai M, Moore DR. Protein Requirements Are Elevated in Endurance Athletes after Exercise as Determined by the Indicator Amino Acid Oxidation Method. PLoS One. 2016 Jun 20;11(6):e0157406. doi: 10.1371/journal.pone.0157406. eCollection 2016.
9 participants (actual enrollment reported by the registry).
First Submitted
June 18, 2015
First Posted
June 23, 2015
Study Start
March 2015
Date type not reportedThis date has not been verified as actual or estimated.
Rate-limiting Amino Acids in Endurance-trained Athlete
Contact the study team to confirm eligibility.
Primary Completion
January 2016
Actual (reported)Study Completion
May 2016
Actual (reported)Last Updated
June 16, 2016
Record last verified: 2016-06
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Source: ClinicalTrials.gov.
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