NCT03163043

Completed

Protein Requirements for Active Children

Daniel Moore Source

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Other study identifiers

Sponsor study identifier

IAAO-C

Study Type

interventional

Actual enrollment (reported)

8

Locations

1 country

Sites

1

Timeline

Study Start

October 22, 2016

Actual (reported)

Primary Completion

October 31, 2017

Actual (reported)

Study Completion

December 31, 2017

Actual (reported)

Brief Summary

Nutritional requirements for dietary amino acids in children have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity in healthy, active children. The purpose of this study is to measure the protein requirement in children (boys and girls) using the IAAO technique in the presence of a variable intensity exercise stimulus. It is hypothesized that the present study will deem current amino acid requirements to be underestimates of appropriate amino acid requirements for this population.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 8 participants
Study completion date: December 31, 2017
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
October 22, 2016
Actual (reported)
First Submitted
May 19, 2017
Actual (reported)
First Posted
May 22, 2017
Actual (reported)
Primary Completion
October 31, 2017
Actual (reported)
Study Completion
December 31, 2017
Actual (reported)

Last Updated: March 29, 2019
Status Verified: March 2019
Last Update Submitted: March 28, 2019

Conditions

Healthy Increased Metabolic Requirement

Outcome Measures

Primary Outcomes (1)

13CO2 ([13]Carbon Dioxide) Excretion (µmol/kg/h)
4 hours/study day

Secondary Outcomes (1)

[13C]Phenylalanine Oxidation (µmol/kg/h)
4 hours/study day

Study Arms (1)

Active, Male and Female Children

EXPERIMENTAL

Participants will receive different levels of amino acid intakes, varying from 0.2-2.67 g/kg/d

Dietary Supplement: Amino Acid Intake

Interventions

Amino Acid IntakeDietary supplement

Amino acid intakes will be varied at 0.2-2.67 g/kg/d

Active, Male and Female Children

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age7 Years - 12 Years

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17)

You may qualify if:

Healthy, active children who regularly participates in moderate to vigorous physical activity 5 times a week for a minimum of 1 hour.
Biological age less than or equal to -1.0 years from Peak Height Velocity (PHV), determined by the ratio of standing to sitting height

Sponsors & Collaborators

Daniel Moore
Otherlead
Ajinomoto Co., Inc.
Industrycollaborator

Study Sites (1)

Goldring Centre For High Performance Sport

Toronto, Ontario, M5S 2C9, Canada

Enrollment

8 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: BASIC SCIENCE
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Dr. Daniel Moore, Assistant Professor

Study Record Dates

First Submitted

May 19, 2017

First Posted

May 22, 2017

Study Start

October 22, 2016

Actual (reported)

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Not ApplicableCompleted

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Not ApplicableCompleted

NCT06431334

Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique

Not ApplicableCompleted

NCT02874638

Effect of Non-essential Amino Acids on Protein Requirements for Endurance Athletes

Not ApplicableCompleted

NCT02628249

Rate-limiting Amino Acids in Endurance-trained Athlete

Not ApplicableCompleted

NCT06785428

Dietary Protein Requirements in Adults With Facioscapulohumeral Muscular Dystrophy

Not ApplicableCompleted

An age and sex-specific minimum performance level on the Beep Test

You may not qualify if:

Inability to meet health and physical activity guidelines according to the PAR-Q+ and Physical Activity Questionnaire
Inability to adhere to any of the protocol guidelines (i.e., caffeine consumption)
Biological age greater than -1.0 years from PHV

Contact the study team to confirm eligibility.

Primary Completion

October 31, 2017

Actual (reported)

Study Completion

December 31, 2017

Actual (reported)

Last Updated

March 29, 2019

Record last verified: 2019-03

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT03163043
Data provider: ClinicalTrials.gov
Source updated: 2019-03-29
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:34:44 UTC

Locations

CA(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (1)

Active, Male and Female Children

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations