NCT00988377

Brief Summary

The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2007

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2007

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2007

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2007

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

September 30, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 2, 2009

Completed
Last Updated

October 2, 2009

Status Verified

October 1, 2009

Enrollment Period

3 months

First QC Date

September 30, 2009

Last Update Submit

October 1, 2009

Conditions

Diabetes PreventionObesity Prevention

Keywords

whey proteinsubjective appetiteshor-term food intakeblood glucose

Outcome Measures

Primary Outcomes (1)

  • Blood glucose subjective appetite Food intake at 30 min

    0-95 min

Secondary Outcomes (1)

  • physical comfort palatability

    0-95 min

Study Arms (5)

10 g whey protein

EXPERIMENTAL
Other: dietary intervention

20 g whey protein

EXPERIMENTAL
Other: dietary intervention

30 g whey protein

EXPERIMENTAL
Other: dietary intervention

40 g whey protein

EXPERIMENTAL
Other: dietary intervention

water control

EXPERIMENTAL

Iso-volumetric (300 ml) water control (Crystal Springs, Canada)

Other: water control

Interventions

dietary interventionOTHER

whey protein 10-40 g

10 g whey protein20 g whey protein30 g whey protein40 g whey protein
water controlOTHER

Iso-volumetric (300 ml) water control (Crystal Springs, Canada)

water control

Eligibility Criteria

Age20 Years - 27 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy
  • normal weight ( 18-24.9 kg/m²)
  • young aged 20-27 year old

You may not qualify if:

  • breakfast skippers
  • smokers
  • dieters
  • individuals with diabetes (fasting BG ≥ 7.0 mmol/L) or other metabolic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Toronto, Department of Nutritional Sciences

Toronto, Ontario, M5S 3E2, Canada

Location

Related Publications (1)

  • Akhavan T, Luhovyy BL, Brown PH, Cho CE, Anderson GH. Effect of premeal consumption of whey protein and its hydrolysate on food intake and postmeal glycemia and insulin responses in young adults. Am J Clin Nutr. 2010 Apr;91(4):966-75. doi: 10.3945/ajcn.2009.28406. Epub 2010 Feb 17.

    PMID: 20164320DERIVED

MeSH Terms

Interventions

Diet Therapy

Intervention Hierarchy (Ancestors)

Nutrition TherapyTherapeutics

Study Officials

  • Harvey Anderson, Ph.D.

    University of Toronto

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 30, 2009

First Posted

October 2, 2009

Study Start

May 1, 2007

Primary Completion

August 1, 2007

Study Completion

November 1, 2007

Last Updated

October 2, 2009

Record last verified: 2009-10

Locations

CA(1)