NCT00988689

Brief Summary

The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular corn or maltodextrin starches or no added starch at one week intervals. The investigators measured food intake at 120 minutes, appetite and blood sugar.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2008

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2008

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2009

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 30, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 2, 2009

Completed
Last Updated

October 2, 2009

Status Verified

September 1, 2009

Enrollment Period

2 months

First QC Date

September 30, 2009

Last Update Submit

September 30, 2009

Conditions

Obesity PreventionDiabetes Prevention

Keywords

starchcarbohydratesblood glucosefood intakesatietyappetite

Outcome Measures

Primary Outcomes (3)

  • Blood glucose

    0-200 min

  • Food Intake

    at 120 min

  • Appetite

    0-200 min

Secondary Outcomes (1)

  • Palatability of treatments

    0-200 min

Study Arms (5)

Soup with no added starch

EXPERIMENTAL
Other: Dietary Intervention

Soup + 50 g of whole grain starch

EXPERIMENTAL
Other: Dietary Intervention

Soup + 50 g of high amylose corn starch

EXPERIMENTAL
Other: Dietary Intervention

Soup + 50 g of regular corn starch

EXPERIMENTAL
Other: Dietary Intervention

Soup + 50 g maltodextrin starch

EXPERIMENTAL
Other: Dietary Intervention

Interventions

Dietary InterventionOTHER

soup with or without starch

Soup + 50 g maltodextrin starchSoup + 50 g of high amylose corn starchSoup + 50 g of regular corn starchSoup + 50 g of whole grain starchSoup with no added starch

Eligibility Criteria

Age20 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy males with a BMI of 20-24.9 kg/m2

You may not qualify if:

  • Females
  • Smokers
  • Breakfast skippers
  • Individuals with diabetes or other metabolic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Nutritional Studies, University of Toronto

Toronto, Ontario, M5S 3E2, Canada

Location

Related Publications (1)

  • Anderson GH, Cho CE, Akhavan T, Mollard RC, Luhovyy BL, Finocchiaro ET. Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men. Am J Clin Nutr. 2010 Apr;91(4):932-9. doi: 10.3945/ajcn.2009.28443. Epub 2010 Feb 17.

    PMID: 20164321DERIVED

MeSH Terms

Interventions

Diet Therapy

Intervention Hierarchy (Ancestors)

Nutrition TherapyTherapeutics

Study Officials

  • Harvey Anderson, Ph.D.

    University of Toronto

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 30, 2009

First Posted

October 2, 2009

Study Start

June 1, 2008

Primary Completion

August 1, 2008

Study Completion

June 1, 2009

Last Updated

October 2, 2009

Record last verified: 2009-09

Locations

CA(1)