NCT00988182

Brief Summary

The purpose of this study is to describe relationships among whey protein and its hydrolysate when consumed before a meal on pre- and post-fixed meal satiety, blood glucose and insulin in healthy young adults.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 30, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 2, 2009

Completed
Last Updated

October 2, 2009

Status Verified

October 1, 2009

First QC Date

September 30, 2009

Last Update Submit

October 1, 2009

Conditions

Diabetes PreventionObesity Prevention

Keywords

Whey proteinHydrolysate whey proteinBlood glucoseInsulin

Outcome Measures

Primary Outcomes (1)

  • Blood glucose, Insulin, Subjective appetite

    0-170 min

Secondary Outcomes (1)

  • Physical comfort

    0-170 min

Study Arms (5)

whey protein, 5g

EXPERIMENTAL
Other: dietary intervention

whey protein, 10g

EXPERIMENTAL
Other: dietary intervention

whey protein, 20g

EXPERIMENTAL
Other: dietary intervention

whey protein, 40g

EXPERIMENTAL
Other: dietary intervention

water control

EXPERIMENTAL
Other: water control

Interventions

dietary interventionOTHER

whey protein

whey protein, 10gwhey protein, 20gwhey protein, 40gwhey protein, 5g
water controlOTHER
water control

Eligibility Criteria

Age20 Years - 27 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • normal body weight

You may not qualify if:

  • breakfast skippers
  • smokers
  • dieters or individuals with diabetes (fasting blood glucose ≥ 7.0 mmol/L) or other metabolic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Toronto, Department of Nutritional Sciences

Toronto, Ontario, M5S 3E2, Canada

Location

Related Publications (1)

  • Akhavan T, Luhovyy BL, Brown PH, Cho CE, Anderson GH. Effect of premeal consumption of whey protein and its hydrolysate on food intake and postmeal glycemia and insulin responses in young adults. Am J Clin Nutr. 2010 Apr;91(4):966-75. doi: 10.3945/ajcn.2009.28406. Epub 2010 Feb 17.

    PMID: 20164320DERIVED

MeSH Terms

Conditions

Insulin Resistance

Interventions

Diet Therapy

Condition Hierarchy (Ancestors)

HyperinsulinismGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Nutrition TherapyTherapeutics

Study Officials

  • Harvey Anderson, Ph.D.

    University of Toronto

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 30, 2009

First Posted

October 2, 2009

Last Updated

October 2, 2009

Record last verified: 2009-10

Locations

CA(1)