A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer
A Phase III Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer
2 other identifiers
interventional
1,613
2 countries
533
Brief Summary
The main purpose of this study is to learn if adding bevacizumab to standard treatment with chemotherapy (docetaxel, doxorubicin, and cyclophosphamide) for early stage HER2-negative breast cancer will prevent breast cancer from returning. A second purpose of this study is to learn if adding bevacizumab to treatment with chemotherapy will help women with HER2-negative breast cancer live longer. The researchers also want to learn about the side effects of the combination of drugs used in this study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3 breast-cancer
Started May 2009
Typical duration for phase_3 breast-cancer
533 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 23, 2009
CompletedFirst Posted
Study publicly available on registry
April 24, 2009
CompletedStudy Start
First participant enrolled
May 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2018
CompletedApril 20, 2022
April 1, 2022
8.8 years
April 23, 2009
April 13, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Invasive disease-free survival(IDFS)relative to the TAC chemotherapy regimen alone
Every 12 months until recurrence
Secondary Outcomes (11)
Invasive disease-free survival (IDFS) relative to the TAC chemotherapy regimen
Every 12 months until recurrence
Disease-free survival (DFS-DCIS) relative to the TC alone regimen
Every 12 months until recurrence
Overall survival (OS) relative to the TC alone regimen
Every 12 months from randomization until death from any cause
OS relative to the TAC regimen
Every 12 months from randomization until death from any cause
Recurrence-free interval (RFI) relative to the TC alone regimen
Every 12 months, from randomization to local, regional, or distant recurrence
- +6 more secondary outcomes
Study Arms (3)
Group 1: TAC then pegfilgrastim
ACTIVE COMPARATORdocetaxel, doxorubicin, cyclophosphamide, and pegfilgrastim/filgrastim
Group 2: TC
ACTIVE COMPARATORdocetaxel and cyclophosphamide
Group 3: TC + bevacizumab
EXPERIMENTALdocetaxel, cyclophosphamide, and bevacizumab
Interventions
bevacizumab 15 mg/kg IV every 21 days for 6 cycles followed by bevacizumab 15 mg/kg IV every 21 days until 1 year following the first dose of bevacizumab
docetaxel 75 mg/m2 IV every 21 days for 6 cycles
doxorubicin 50 mg/m2 IV every 21 days for 6 cycles
Group 1: cyclophosphamide 500 mg/m2 IV every 21 days for 6 cycles Group 2 and 3: cyclophosphamide 600 mg/m2 IV every 21 days for 6 cycles
pegfilgrastim 6 mg subcutaneous (SC) Day 2 every 21 days for 6 cycles \[filgrastim (Neupogen®) 5 mcg/kg Days 2-10 may be given in lieu of pegfilgrastim (Neulasta®), but pegfilgrastim is preferred.\]
Eligibility Criteria
You may qualify if:
- Patients must be female.
- The patient must be greater than or equal to 18 years of age and less than or equal to 70 years of age.
- The patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
- The tumor must be unilateral invasive adenocarcinoma of the breast on histologic examination.
- The breast cancer must be HER2-negative based on current American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) Guideline Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer. If the result of the in situ hybridization testing (FISH, chromagen in situ hybridization (CISH), or other) is equivocal, the patient is eligible if there is no plan to administer HER2-targeted therapy.
- All of the following staging criteria (according to the 6th edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual) must be met: By pathologic evaluation, primary tumor must be pT1-3; By pathologic evaluation, ipsilateral nodes must be pN0, pN1 (pN1mi, pN1a, pN1b, pN1c), pN2a, pN3a, or pN3b. If pN0, at least one of the following criteria must be met: ER negative and PgR negative; or Pathologic tumor size greater than 2.0 cm; or T1c (pathologic tumor size greater than 1.0 cm but less than or equal to 2.0 cm) and ER positive (PgR status may be positive or negative) and either Oncotype DX® Recurrence Score of greater than or equal to 25 or grade 3 histology.
- Patients must have undergone either a total mastectomy or breast-conserving surgery (lumpectomy).
- For patients who undergo lumpectomy, the margins of the resected specimen must be histologically free of invasive tumor and DCIS as determined by the local pathologist. If pathologic examination demonstrates tumor at the line of resection, additional operative procedures must be performed to obtain clear margins. If tumor is still present at the resected margin after re-excision(s), the patient must undergo total mastectomy to be eligible. (Patients with margins positive for lobular carcinoma in situ \[LCIS\] are eligible without additional resection.)
- For patients who undergo mastectomy, margins must be histologically free of invasive tumor and DCIS.
- Patients must have completed one of the following procedures for evaluation of pathologic nodal status: Sentinel lymphadenectomy alone if pathologic nodal staging based on sentinel lymphadenectomy is pN0, pN1mi, or pN1b; Sentinel lymphadenectomy followed by removal of additional non-sentinel lymph nodes if the sentinel node (SN) is positive; or Axillary lymphadenectomy without SN isolation procedure.
- The interval between the last surgery for breast cancer (treatment or staging) and randomization must be at least 28 days but no more than 84 days.
- Patients must have ER analysis performed on the primary tumor prior to randomization. If ER analysis is negative, then PgR analysis must also be performed. (Either a core biopsy or surgical resection specimen can be used for ER/PgR testing.)
- The most recent postoperative blood counts must meet the following criteria: Absolute neutrophil count (ANC) must be greater than or equal to 1200/mm3; platelet count must be greater than or equal to 100,000/mm3; and hemoglobin must be greater than or equal to 10 g/dL.
- The following criteria for evidence of adequate hepatic function must be met based on the results of the most recent postoperative tests: total bilirubin must be less than or equal to upper limits of normal (ULN)for the lab unless the patient has a bilirubin elevation less than ULN to 1.5 x ULN due to Gilbert's disease or similar syndrome involving slow conjugation of bilirubin; and alkaline phosphatase must be less than or equal to 2.5 x ULN for the lab; and AST must be less than or equal to 1.5 x ULN for the lab. Alkaline phosphatase and aspartate transaminase (AST) may not both be greater than the ULN. For example, if the alkaline phosphatase is greater than the ULN but less than or equal to 2.5 x ULN, then the AST must be less than or equal to the ULN. If the AST is greater than the ULN but less than or equal to 1.5 x ULN, then the alkaline phosphatase must be less than or equal to ULN.
- The most recent postoperative serum creatinine must be less than or equal to ULN for the lab.
- +2 more criteria
You may not qualify if:
- T4 tumors including inflammatory breast cancer.
- Definitive clinical or radiologic evidence of metastatic disease.
- Synchronous or metachronous contralateral invasive breast cancer. (Patients with synchronous and/or metachronous contralateral DCIS are eligible.)
- Any history of ipsilateral invasive breast cancer or ipsilateral DCIS.
- History of non-breast malignancies within 5 years prior to randomization, except for the following: carcinoma in situ of the cervix, colorectal carcinoma in situ, melanoma in situ, and basal cell and squamous cell carcinomas of the skin.
- Previous therapy with anthracyclines, taxanes, or bevacizumab for any malignancy.
- Chemotherapy administered for the currently diagnosed breast cancer prior to randomization.
- Continued therapy with any hormonal agent such as raloxifene or tamoxifen (or other SERM) or an aromatase inhibitor. (Patients are eligible if these medications are discontinued prior to randomization.)
- Any sex hormonal therapy, e.g., birth control pills, ovarian hormone replacement therapy. Patients are eligible if these medications are discontinued prior to randomization.
- Active hepatitis B or hepatitis C with abnormal liver function tests.
- Cardiac disease (history of and/or active disease) that would preclude the use of the drugs included in the treatment regimens. This includes but is not confined to 1) Active cardiac disease: angina pectoris that requires the use of anti-anginal medication; ventricular arrhythmias except for benign premature ventricular contractions; supraventricular and nodal arrhythmias requiring a pacemaker or not controlled with medication; conduction abnormality requiring a pacemaker; valvular disease with documented compromise in cardiac function; and symptomatic pericarditis, 2) History of cardiac disease: myocardial infarction documented by elevated cardiac enzymes or persistent regional wall abnormalities on assessment of left ventricular (LV) function; history of documented congestive heart failure (CHF); and documented cardiomyopathy.
- Uncontrolled hypertension defined as systolic BP greater than 150 mmHg or diastolic BP greater than 90 mmHg, with or without anti-hypertensive medication. Patients with initial BP elevations are eligible if initiation or adjustment of BP medication lowers pressure to meet entry criteria.
- History of hypertensive crisis or hypertensive encephalopathy.
- History of transient ischemic attack (TIA) or cerebrovascular accident (CVA).
- History of any arterial thrombotic event within 12 months prior to randomization.
- +21 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- NSABP Foundation Inclead
- Genentech, Inc.collaborator
- US Oncology Researchcollaborator
Study Sites (533)
Birmingham Hematology and Oncology
Bessemer, Alabama, 35022, United States
Birmingham Hematology and Oncology
Birmingham, Alabama, 35205, United States
Birmingham Hematology and Oncology - Brookwood
Birmingham, Alabama, 35209, United States
Birmingham Hematology and Oncology - Princeton
Birmingham, Alabama, 35211, United States
Birmingham Hematology and Oncology - Montclair
Birmingham, Alabama, 35213, United States
Birmingham Hematology and Oncology - Pilot
Birmingham, Alabama, 35235, United States
Clearview Cancer Institute- Huntsville
Huntsville, Alabama, 35805, United States
Northern Arizona Hematology & Onclogy Associates
Flagstaff, Arizona, 86001, United States
Arizona Oncolocy (CASA-Green Valley)
Green Valley, Arizona, 85614, United States
Arizona Oncology (CASA- Oro Valley)
Oro Valley, Arizona, 85737, United States
Hematology Oncology Associates
Phoenix, Arizona, 85012, United States
Northern Arizona Hematology & Oncology Associates
Prescott Valley, Arizona, 86314, United States
Arizona Oncology (CASA-Safford)
Safford, Arizona, 85546, United States
Hematology Oncology Associates
Scottsdale, Arizona, 85258, United States
Northern Arizona Hematology & Oncology Associates
Sedona, Arizona, 86336, United States
Arizona Oncology Associates - Rudasill
Tucson, Arizona, 85704, United States
Arizona Oncology Associates - Carondelet
Tucson, Arizona, 85710, United States
Arizona Oncology (CASA-Craycroft)
Tucson, Arizona, 85712, United States
Arizona Oncology (CASA-Office Only)
Tucson, Arizona, 85715, United States
Arizona Oncology - CASA St. Mary's
Tucson, Arizona, 85745, United States
Central Hematology/Oncology Medical Group, Inc.
Alhambra, California, 91801, United States
Kaiser Permanente Deer Valley Med Center
Antioch, California, 94531, United States
Comp Blook and Cancer Center
Bakersfield, California, 93309, United States
Southwest Cancer Care (E. Grand)
Escondido, California, 92025, United States
Kaiser Permanente Fremont
Fremont, California, 94538, United States
St. Jude Heritage Healthcare
Fullerton, California, 92835, United States
Kaiser Permanente Medical Center - Hayward
Hayward, California, 94545, United States
Pacific Shores Medical Group
Huntington Beach, California, 92648, United States
Southern California Permanente Medical Group
Irvine, California, 92618, United States
Wilshire Oncology Medical Group (Business Office)
La Verne, California, 91750, United States
Antelope Valley Cancer Center
Lancaster, California, 93534, United States
Breastlink Medical Group, Incorporated at Long Beach Memorial Medical Center
Long Beach, California, 90806, United States
Todd Cancer Institute at Long Beach Memorial Med Cent
Long Beach, California, 90806, United States
Pacific Shores Medical Group
Long Beach, California, 90813, United States
Pacific Shores Medical Group
Los Alamitos, California, 90720, United States
TORI- N Valley Hematology Oncology Med Group
Mission Hills, California, 91345, United States
TORI - Oncology Care Medical Assoc.
Montebello, California, 90640, United States
Southwest Cancer Care (Medical Center)
Murrieta, California, 92562, United States
NValley Hematology/Oncology Medical Group
Northridge, California, 91325, United States
Kaiser Permanente-Oakland
Oakland, California, 94611, United States
St. Joseph Hospital
Orange, California, 92868, United States
Ventura County Hematology-Oncology Specialists
Oxnard, California, 93030, United States
Stanford University Medical Center
Palo Alto, California, 94304, United States
Kaiser Permanente Medical Center - Redwood City
Redwood City, California, 94063, United States
Kaiser Permanente Medical Center - Richmond
Richmond, California, 94801, United States
Sutter Roseville Medical Center
Roseville, California, 95661, United States
Kaiser Permanente Roseville
Roseville, California, 95678, United States
Sutter Medical Center
Sacramento, California, 95816, United States
Kaiser Permanente, South Sacramento
Sacramento, California, 95823, United States
Kaiser Permanente Medical Center - Sacramento
Sacramento, California, 95825, United States
Kaiser Permanente-San Diego
San Diego, California, 92120, United States
Kaiser Permanente Medical Center - San Francisco Geary Campus
San Francisco, California, 94115, United States
TORI - Oncology Care Med Assoc
San Gabriel, California, 91776, United States
Kaiser Permanente Santa Teresa
San Jose, California, 95119, United States
Kaiser Permanente San Rafael
San Rafael, California, 94903, United States
Santa Barbara Hematology Oncology Medical Group
Santa Barbara, California, 93105, United States
Santa Barbara II (Samsum Clinic) - TORI
Santa Barbara, California, 93105, United States
Kaiser Permanente Medical Center - Santa Clara Kiely Campus
Santa Clara, California, 95051, United States
Central Coast Medical Oncology Corporation
Santa Maria, California, 93454, United States
Kaiser Permanente Medical Center - Santa Rosa
Santa Rosa, California, 95403, United States
Santa Barbara Hematology/Oncology Medical Group, Inc
Solvang, California, 93463, United States
Kaiser Permanente-South San Francisco
South San Francisco, California, 94080, United States
Kaiser Permanente Medical Facility - Stockton
Stockton, California, 95210, United States
Olive View/UCLA Medical Center
Sylmar, California, 91342, United States
Kaiser Permanente Medical Center Vacaville
Vacaville, California, 95688, United States
Kaiser Permanente Medical Center - Vallejo
Vallejo, California, 94589, United States
Kaiser Permanente Medical Center - Walnut Creek
Walnut Creek, California, 94596, United States
Trivalley Oncology Hematology
Westlake Village, California, 91361, United States
Westlake Infusion Center
Westlake Village, California, 91361, United States
TORI - Oncology Care Med Assoc
Whittier, California, 90602, United States
Medical Center of Aurora
Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Center
Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Centers - Boulder
Boulder, Colorado, 80303, United States
Penrose/St. Francis Healthcare System
Colorado Springs, Colorado, 80907, United States
Rocky Mountain Cancer Center at the Pivillion- Fontanero
Colorado Springs, Colorado, 80907, United States
Rocky Mountain Cancer Center - CO Springs
Colorado Springs, Colorado, 80909, United States
Kaiser Permanente-Franklin
Denver, Colorado, 80205, United States
CCOP - Colorado Cancer Research Program, Inc.
Denver, Colorado, 80209-5031, United States
Porter Adventist Hospital
Denver, Colorado, 80210, United States
Exempla St. Joseph Hospital
Denver, Colorado, 80218, United States
Rocky Mountain Cancer Center - Midtown
Denver, Colorado, 80218, United States
Rocky Mountain Cancer Center - 9th Avenue
Denver, Colorado, 80220, United States
Rocky Mountain Cancer Center - Rose
Denver, Colorado, 80220, United States
University of Colorado
Denver, Colorado, 80262, United States
Shaw Regional Cancer Center
Edwards, Colorado, 81632, United States
Swedish Medical Center
Englewood, Colorado, 80110, United States
Front Range Cancer Specialists
Fort Collins, Colorado, 80524, United States
Poudre Valley Hospital
Fort Collins, Colorado, 80524, United States
St. Mary's Hospital and Medical Center
Grand Junction, Colorado, 81502-1628, United States
St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
Grand Junction, Colorado, 81502, United States
North Colorado Medical Center
Greeley, Colorado, 80631, United States
Kaiser Permanente Rock Creek
Lafayette, Colorado, 80026, United States
Rocky Mountain Cancer Center
Lakewood, Colorado, 80228, United States
Rocky Mountain Cancer Center - Dry Creek
Littleton, Colorado, 80120-4413, United States
Rocky Mountain Cancer Center- Sky Ridge
Lone Tree, Colorado, 80124, United States
Rocky Mountain Cancer Center - Longmont
Longmont, Colorado, 80501, United States
McKee Medical Center
Loveland, Colorado, 80539, United States
Rocky Mountain Cancer Center
Parker, Colorado, 80138, United States
Rocky Mountain Cancer Centers
Thornton, Colorado, 80260, United States
Exempla Lutheran Medical Center
Wheat Ridge, Colorado, 80033, United States
University of Connecticut
Farmington, Connecticut, 06032, United States
Hartford Hospital
Hartford, Connecticut, 06102-5037, United States
Washington Regional Cancer Center
Washington D.C., District of Columbia, 20010, United States
Sibley Memorial Hospital
Washington D.C., District of Columbia, 20016, United States
SCRI - Florida Cancer Specialists- Bonita Springs
Bonita Springs, Florida, 34135, United States
SCRI - Florida Cancer Specialists - Bradenton
Bradenton, Florida, 34209, United States
Florida Cancer Specialists
Brandon, Florida, 33511, United States
SCRI Florida Cancer Specialists - Cape Coral (1708)
Cape Coral, Florida, 33914, United States
SCRI Florida Cancer Specialists - Cape Coral (811)
Cape Coral, Florida, 33990, United States
Morton Plant Mease Health Care
Clearwater, Florida, 33756, United States
SCRI Florida Cancer Specialists - Englewood
Englewood, Florida, 33990, United States
Holy Cross Hospital
Fort Lauderdale, Florida, 33308, United States
SCRI Florida Cancer Specialists - Fort Myers (Hampshire)
Fort Myers, Florida, 33908, United States
SCRI Florida Cancer Specialists - Ft. Myers (Broadway)
Fort Myers, Florida, 33908, United States
SCRI Florida Cancer Specialists- Fort Myers (Veronica)
Fort Myers, Florida, 33916, United States
University of Florida Shands Cancer Center
Gainesville, Florida, 32610-0232, United States
Florida Cancer Institute - New Hope
Hudson, Florida, 34667, United States
TORI-ICON - Shircl
Jacksonville, Florida, 32204, United States
Baptist Cancer Institute - Jacksonville
Jacksonville, Florida, 32207, United States
Integrated Community Oncology Network (ICON)
Jacksonville, Florida, 32207, United States
TORI-ICON St.Aug
Jacksonville, Florida, 32258, United States
CCOP, Jupiter Medical Cener
Jupiter, Florida, 33458, United States
Ocala Oncology Center - Lady Lake
Lady Lake, Florida, 32159, United States
Melbourne International Medicine Associates
Melbourne, Florida, 32901, United States
Advanced Medical Specialties - AMS
Miami, Florida, 33133, United States
Advanced Medical Specialists- Sunset
Miami, Florida, 33143, United States
Advanced Medical Specialties - N Kendall (STE 300E)
Miami, Florida, 33176, United States
Advanced Medical Specialties - N. Kendall (STE 905E)
Miami, Florida, 33176, United States
CCOP - Mount Sinai Medical Center
Miami Beach, Florida, 33140, United States
SCRI Florida Cancer Specialists - Naples (Goodlette)
Naples, Florida, 34102, United States
SCRI Florida Cancer Specialists - Naples (Pine)
Naples, Florida, 34119, United States
Florida Cancer Institute - New Hope
New Port Richey, Florida, 34655, United States
Ocala Oncology Center
Ocala, Florida, 34478, United States
Cancer Centers of Florida, P.A.
Ocoee, Florida, 34761, United States
Tori-Icon
Orange Park, Florida, 32073, United States
Florida Hospital
Orlando, Florida, 32803, United States
Cancer Centers of Florida, P.A.
Orlando, Florida, 32806, United States
MD Anderson Cancer Center
Orlando, Florida, 32806, United States
SCRI - Florida Cancer Specialists - Port Charlotte
Port Charlotte, Florida, 33980, United States
Tori-Icon
Saint Augustine, Florida, 32086, United States
SCRI Florida Cancer Specialists - Sarasota (Cattleman)
Sarasota, Florida, 34232, United States
SCRI- Florida Cancer Specialists - Sarasota
Sarasota, Florida, 34236, United States
SCRI - Florida Cancer Specialists - Armenia
Tampa, Florida, 33603, United States
SCRI - Florida Cancer Specialists - Tampa
Tampa, Florida, 33607, United States
SCRI Florida Cancer Specialists - Venice (Tamiami)
Venice, Florida, 34285, United States
SCRI Florida Cancer Specilaists - Venice
Venice, Florida, 34292, United States
Cancer Centers of Florida, P.A.
Winter Park, Florida, 32789, United States
Phoebe Putney Memorial Hospital
Albany, Georgia, 31703, United States
Northwest Georgia Oncology Centers
Austell, Georgia, 30106, United States
Northwest Georgia Oncology Centers
Carrollton, Georgia, 30117, United States
Dublin Hematology/Oncology
Dublin, Georgia, 31021, United States
Suburban Hematology-Oncology Associates
Lawrenceville, Georgia, 30045, United States
Northwest Georgia Oncology Centers
Marietta, Georgia, 30060, United States
SCRI Chattanooga Oncol & Hematol Assoc, PC - Ringgold
Ringgold, Georgia, 30736, United States
Memorial Health University Medical Center
Savannah, Georgia, 31404, United States
University of Hawaii
Honolulu, Hawaii, 96813, United States
Kaiser Permanente Hawaii - Moanalua Med Center
Honolulu, Hawaii, 96819, United States
Cancer Care & Hematology Specialists of Chicagoland
Arlington, Illinois, 60005, United States
Rush University Medical Center
Chicago, Illinois, 60612, United States
Decatur Memorial Hospital Cancer Care Institute
Decatur, Illinois, 62526, United States
CCOP NorthShore University HealthSystem
Evanston, Illinois, 60201, United States
Ingalls Memorial Hospital
Harvey, Illinois, 60426, United States
Hinsdale Hematology Oncology Associates
Hinsdale, Illinois, 60521, United States
Edward Hospital
Naperville, Illinois, 60566, United States
Cancer Care & Hematology Specialists of Chicagoland
Niles, Illinois, 60714, United States
Advocate Lutheran General Cancer Care Center
Park Ridge, Illinois, 60068-1174, United States
Carle Cancer Center, CCOP
Urbana, Illinois, 61801, United States
Carle Foundation Hospital
Urbana, Illinois, 61801, United States
Cancer Care and Hematology Specialists of Chicagoland
Winfield, Illinois, 60190, United States
Central Indiana Cancer Centers
Carmel, Indiana, 46032, United States
Central Indiana Cancer Centers
Fishers, Indiana, 46037, United States
Central Indiana Cancer Centers
Greenfield, Indiana, 46140, United States
Central Indiana Cancer Centers
Indianapolis, Indiana, 46219, United States
Central Indiana Cancer Centers (E. County)
Indianapolis, Indiana, 46227, United States
St. Vincent Hospital and Health Care Center
Indianapolis, Indiana, 46260, United States
Clarian Arnett Cancer Care
Lafayette, Indiana, 47904, United States
Community Hospital
Munster, Indiana, 46321, United States
Genesis Medical Center
Davenport, Iowa, 52803, United States
Finley Hospital
Dubuque, Iowa, 52001-6314, United States
University of Iowa
Iowa City, Iowa, 52242, United States
Mercy Medical Center - Sioux City
Sioux City, Iowa, 51101, United States
Siouxland Hematology-Oncology Associates
Sioux City, Iowa, 51101, United States
St. Luke's Regional Medical Center
Sioux City, Iowa, 51101, United States
Covenant Cancer Treatment Center
Waterloo, Iowa, 50702, United States
Kansas Cty Cancer Center - West
Kansas City, Kansas, 66112, United States
Menorah Medical Center
Overland Park, Kansas, 66209, United States
Kansas City Cancer Center (CBO)
Overland Park, Kansas, 66210, United States
Kansas CityCancer Centers - Southwest
Overland Park, Kansas, 66210, United States
Kansas City Cancer Center, Shawnee Mission
Shawnee Mission, Kansas, 66204, United States
SCRI Oncology Hematology Care, Inc. Crestview Hills (CVH)
Crestview Hills, Kentucky, 41017, United States
University of Kentucky Medical Center
Lexington, Kentucky, 40536, United States
NortonHealtcare Inc.
Louisville, Kentucky, 40202, United States
Consultants in Blood Disorders and Cancer
Louisville, Kentucky, 40207, United States
Christus St. Frances Cabrini Hospital
Alexandria, Louisiana, 71301, United States
Baton Rouge General Medical Center
Baton Rouge, Louisiana, 70806, United States
Tulane University Medical Center
New Orleans, Louisiana, 70112, United States
Eastern Maine Medical Center
Bangor, Maine, 04401, United States
Mercy Medical Center
Baltimore, Maryland, 21202, United States
St. Joseph's Medical Center
Baltimore, Maryland, 21204-7582, United States
Greater Baltimore Medical Center
Baltimore, Maryland, 21204, United States
Franklin Square Hospital Center
Baltimore, Maryland, 21237, United States
SCRI - Center for Cancer and Blood Disorders
Bethesda, Maryland, 20817, United States
Suburban Hospital
Bethesda, Maryland, 20817, United States
Chevy Chase Healthcare Management, LLC
Chevy Chase, Maryland, 20815, United States
Maryland Oncology Hematology PA
Columbia, Maryland, 21044, United States
Frederick Memorial Hospital
Frederick, Maryland, 21701, United States
Alliance Hematology Oncology PA
Owings Mills, Maryland, 21117, United States
Penisula Regional Medical Center
Salisbury, Maryland, 21801, United States
Holy Cross Hospital
Silver Spring, Maryland, 20910, United States
Alliance Hematology Oncology PA
Westminster, Maryland, 21157, United States
Saint Anne's Hospital
Fall River, Massachusetts, 02721, United States
Berkshire Hematology Oncology, P.C.
Pittsfield, Massachusetts, 01201, United States
CCOP, St. Joseph Mercy Hospital
Ann Arbor, Michigan, 48106, United States
Bay Regional Medical Center
Bay City, Michigan, 48706, United States
CCOP - Oakwood Hospital and Medical Center
Dearborn, Michigan, 48123-2500, United States
Henry Ford Health System
Detroit, Michigan, 48202, United States
CCOP - St. John Hospital and Medical Center
Detroit, Michigan, 48236-2172, United States
Michigan State University
East Lansing, Michigan, 48824, United States
CCOP - Genesys Regional Hospital
Flint, Michigan, 48503, United States
CCOP - Hurley Medical Center
Flint, Michigan, 48503, United States
McLaren Regional Medical Center
Flint, Michigan, 48532, United States
CCOP - Allegiance Health
Jackson, Michigan, 49201, United States
Borgess Medical Center
Kalamazoo, Michigan, 49001, United States
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007, United States
West Michigan Cancer Center
Kalamazoo, Michigan, 49007, United States
Ingham Regional Medical Center - Lansing
Lansing, Michigan, 48910-0817, United States
CCOP, Sparrow Health System
Lansing, Michigan, 48910, United States
Lapeer Regional Hospital
Lapeer, Michigan, 48446, United States
CCOP - St. Mary Mercy Hospital - Livonia
Livonia, Michigan, 48154, United States
Marquette General Hospital
Marquette, Michigan, 49855, United States
Mount Clemens Regional Medical Center
Mount Clemens, Michigan, 48043, United States
Memorial Healthcare
Owosso, Michigan, 48867, United States
CCOP - St. Joseph Mercy Hospital - Oakland
Pontiac, Michigan, 48341, United States
CCOP - St. Joseph Mercy Port Huron
Port Huron, Michigan, 48060, United States
CCOP, William Beaumont Hospital
Royal Oak, Michigan, 48073, United States
CCOP, St. Mary's Medical Center
Saginaw, Michigan, 48601, United States
Providence Hospital - Southfield
Southfield, Michigan, 48075-9975, United States
CCOP, St. John Macomb Hospital
Warren, Michigan, 48093, United States
Minnesota Oncology Hematology-Burnsville
Burnsville, Minnesota, 55337, United States
Mercy and Unity Cancer Center at Mercy Hospital
Coon Rapids, Minnesota, 55433, United States
St. Luke's Hospital
Duluth, Minnesota, 55802, United States
Fairview Southdale Hospital
Edina, Minnesota, 55435, United States
Minnesota Oncology Hematology-Edina
Edina, Minnesota, 55435, United States
Unity Hospital
Fridley, Minnesota, 55432, United States
Minnesota Oncology Hematology PA - Maplewood
Maplewood, Minnesota, 55109, United States
St. John's Hospital Northeast/HealthEast, Inc.
Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology-Minneapolis
Minneapolis, Minnesota, 55404, United States
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407, United States
Hennepin County Medical Center - Minneapolis
Minneapolis, Minnesota, 55415, United States
North Memorial Health Care
Robbinsdale, Minnesota, 55422, United States
CCOP - Metro-Minnesota
Saint Louis Park, Minnesota, 55416, United States
Park Nicollet Health Services
Saint Louis Park, Minnesota, 55416, United States
Regions Hospital Cancer Care Center
Saint Paul, Minnesota, 55101, United States
Minnesota Hematology Oncology-St. Paul
Saint Paul, Minnesota, 55102, United States
Minnesota Oncology Hematology
Woodbury, Minnesota, 55125, United States
Missouri Cancer Associates
Columbia, Missouri, 65201, United States
University of Missouri-Ellis Fischel
Columbia, Missouri, 65203, United States
Kansas City Cancer Center - Central
Kansas City, Missouri, 64111, United States
Saint Luke's Hospital
Kansas City, Missouri, 64111, United States
CCOP - Kansas City
Kansas City, Missouri, 64131, United States
Kansas City Cancer Center - South
Kansas City, Missouri, 64131, United States
Research Medical Center
Kansas City, Missouri, 64131, United States
Research Medical Center
Kansas City, Missouri, 64132, United States
Kansas City Cancer Center - North
Kansas City, Missouri, 64154, United States
Kansas City Cancer Centers - East
Lee's Summit, Missouri, 64064, United States
St. Louis University Health Sciences Center
St Louis, Missouri, 63110-0250, United States
Nebraska Cancer Research Center
Lincoln, Nebraska, 68510, United States
St. Elizabeth Community Health Center
Lincoln, Nebraska, 68510, United States
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122, United States
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124, United States
CCOP, Missouri Valley Cance Consortium
Omaha, Nebraska, 68131, United States
Creighton University Cancer Center
Omaha, Nebraska, 68131, United States
Alegent Health Midlands Hospital
Papillion, Nebraska, 68046, United States
Comprehensive Cancer Centers of Nevada (Siena)
Henderson, Nevada, 89052, United States
US Oncology West Region Office (Horizon Ridge)
Henderson, Nevada, 89052, United States
Comprehensive Cancer Centers of Nevada (Wigwam)
Henderson, Nevada, 89074, United States
Comprehensive Cancer Centers of Nevada (Peak Dr.)
Las Vegas, Nevada, 89128, United States
Comprehensive Cancer Centers of Nevada (Southern Hills)
Las Vegas, Nevada, 89148, United States
Comprehensive Cancer Centers of Nevada (Twain)
Las Vegas, Nevada, 89169, United States
Renown Regional Medical Center
Reno, Nevada, 89502, United States
Cancer Institute of New Jersey at Hamilton
Hamilton, New Jersey, 08690, United States
Hematology-Oncology Associates of NNJ, PA
Morristown, New Jersey, 07960, United States
Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901, United States
Newark Beth Israel Medical Center
Newark, New Jersey, 07112, United States
Saint Clare's Center at Parsippany Commons
Parsippany, New Jersey, 07054, United States
Somerset Medical Center
Somerville, New Jersey, 08876, United States
Sparta Cancer Center
Sparta, New Jersey, 07871, United States
Texas Oncology PA Las Cruces
Las Cruces, New Mexico, 88011, United States
New Mexico Cancer Care Associates
Santa Fe, New Mexico, 87505, United States
New York Oncology Hematology PC-Albany
Albany, New York, 12206, United States
New York Oncology Hematology, PC at Albany Medical Center
Albany, New York, 12208, United States
Amsterdam Community Cancer Program
Amsterdam, New York, 12010, United States
Interlakes Oncology Hematology PC
Brockport, New York, 14420, United States
Interlakes Oncology & Hematology, P.C.
Canandaigua, New York, 14424, United States
Interlakes Oncology Hematology PC
Geneva, New York, 14456, United States
Cancer Center at Glens Falls Hospital
Glens Falls, New York, 12801, United States
New York Oncology Hematology, P.C. at Cavell Cancer Treatment Program
Hudson, New York, 12534, United States
New York Oncology Hematology, PC
Latham, New York, 12110, United States
CCOP - North Shore University Hospital
Manhasset, New York, 11030, United States
CCOP, Long Island Jewish Medical Center
New Hyde Park, New York, 11040, United States
New York University School of Medicine
New York, New York, 10016, United States
New York Oncology Hematology PC
Rexford, New York, 12148, United States
Interlakes Oncology Hematology PC - White Spruce
Rochester, New York, 14623, United States
Interlakes Oncology Hematology PC- Long Pond
Rochester, New York, 14626, United States
University Hospital and Medical Center - SUNY Stony Brook
Stony Brook, New York, 11794, United States
Troy Cancer Treatment Program
Troy, New York, 12180, United States
Alamance Regional Medical Center
Burlington, North Carolina, 27217, United States
Cancer Centers of North Carolina
Cary, North Carolina, 27518, United States
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
CCOP Carolinas HealthCare System
Charlotte, North Carolina, 28232-2861, United States
Presbyterian Hospital
Charlotte, North Carolina, 28233, United States
Regional Cancer Care, PA
Durham, North Carolina, 27704, United States
Virginia Oncology Associates
Elizabeth City, North Carolina, 27909, United States
Cape Fear Valley Medical Center Cancer Center
Fayetteville, North Carolina, 28302-2000, United States
Wayne Memorial Hospital, Incorporated
Goldsboro, North Carolina, 27534, United States
CCOP, Moses Cone Health System-Regional CA Cntr
Greensboro, North Carolina, 27401, United States
East Carolina University
Greenville, North Carolina, 27834, United States
Margaret R. Pardee Memorial Hospital
Hendersonville, North Carolina, 28791, United States
High Point Regional Hospital
High Point, North Carolina, 27261, United States
Cancer Centers of North Carolina
Raleigh, North Carolina, 27607, United States
Cancer Centers of North Carolina- North Raleigh
Raleigh, North Carolina, 27614, United States
CCOP Forsyth Memorial Hospital
Winston-Salem, North Carolina, 27103, United States
Innovis Health
Fargo, North Dakota, 58103, United States
Akron City Hospital
Akron, Ohio, 44304, United States
Aultman Hospital
Canton, Ohio, 44710, United States
SCRI Oncology Hematology Care, Inc. - Cincinnati (TFT)
Cincinnati, Ohio, 45219, United States
SCRI Oncology Hematology Care, Inc - Cincinnati (AND)
Cincinnati, Ohio, 45230, United States
SCRI Oncology Hematology Care, Inc. - Cincinnati (KWD)
Cincinnati, Ohio, 45236, United States
SCRI Oncology Hematlogy Care, Inc. - Cincinnati (RPR)
Cincinnati, Ohio, 45238, United States
SCRI Oncology Hematology Care, Inc - Cincinnati (BAM)
Cincinnati, Ohio, 45242, United States
SCRI Oncology Hematology Care, Inc. Cincinnati (WST)
Cincinnati, Ohio, 45248, United States
Good Samaritan Hospital
Dayton, Ohio, 45408, United States
CCOP - Dayton
Dayton, Ohio, 45429, United States
HemOnc Care, Inc.
Fairfield, Ohio, 45014, United States
Atrium Medical Center - Middletown Regional Hosp
Franklin, Ohio, 45005-1066, United States
Wayne Hospital
Greenville, Ohio, 45331, United States
SCRI Oncology Hematology Care, Inc. - Hamilton (HAM)
Hamilton, Ohio, 45013, United States
Greater Dayton Cancer Center
Kettering, Ohio, 45409, United States
Kettering Medical Center
Kettering, Ohio, 45429, United States
Upper Valley Medical Center
Troy, Ohio, 45373, United States
Clinton Memorial Hospital
Wilmington, Ohio, 45177, United States
SCRI Oncology Hematology Care, Inc. - Wilmington (WLM)
Wilmington, Ohio, 45177, United States
St. Charles Medical Center - Bend
Bend, Oregon, 97701, United States
Willamette Valley Cancer Institute and Research Center
Eugene, Oregon, 97401, United States
Northwest Cancer Specialists-Portland
Portland, Oregon, 97213, United States
Providence Medical Center
Portland, Oregon, 97213, United States
Northwest Cancer Specialists- St. Vincent
Portland, Oregon, 97225, United States
Providence St. Vincent Medical Center
Portland, Oregon, 97225, United States
Northwest Cancer Specialists- Rose Qtr
Portland, Oregon, 97227, United States
Williamette Valley Cancer Institute and Research Center
Springfield, Oregon, 97477, United States
Celilo Center for Cancer Care
The Dalles, Oregon, 97058, United States
Northwest Cancer Specialists-Tualatin
Tualatin, Oregon, 97062, United States
Geisinger Clinic
Danville, Pennsylvania, 17882-2111, United States
Oncology Hematology Associates of Northern PA
DuBois, Pennsylvania, 15801, United States
Pocono Medical Center
East Stroudsburg, Pennsylvania, 18301, United States
Ephrata Community Hopital
Ephrata, Pennsylvania, 17522-1002, United States
Geisinger Hazleton Cancer Center
Hazleton, Pennsylvania, 18201, United States
Medical Oncology Associates
Kingston, Pennsylvania, 18704, United States
Riddle Memorial Hospital
Media, Pennsylvania, 19063, United States
Rittenhouse Hematology/Oncology
Philadelphia, Pennsylvania, 19107, United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
Albert Einstein Healthcare Network
Philadelphia, Pennsylvania, 19141-3098, United States
Allegheny General Hospital/Allegheny-Singer Research Institute
Pittsburgh, Pennsylvania, 15212, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, 15232-1305, United States
Hematology and Oncology Associates of NEPA
Scranton, Pennsylvania, 18501, United States
Scranton Hematology Oncology
Scranton, Pennsylvania, 18510, United States
Geisinger Medical Group - Scenery Park
State College, Pennsylvania, 16801, United States
Associates in Hematology-Oncology, PC at Crozer Regional Cancer Center
Upland, Pennsylvania, 19013, United States
Reading Hospital and Medical Center
West Reading, Pennsylvania, 19611, United States
Geisinger Wyoming Valley Medical Center
Wilkes-Barre, Pennsylvania, 18711, United States
AnMed Health Cancer Center
Anderson, South Carolina, 29621, United States
Roper Hosp & Med Asso (Care Alliance Health)
Charleston, South Carolina, 29401, United States
Medical University of South Carolina
Charleston, South Carolina, 29425-0721, United States
SCRI - South Carolina Oncology Associates - Stoneridge
Columbia, South Carolina, 29210, United States
Cancer Centers of the Carolinas Easley, SC
Easley, South Carolina, 29640, United States
Georgetown Hospital System
Georgetown, South Carolina, 29440, United States
Cancer Centers of the Carolinas (Butternut)
Greenville, South Carolina, 29605, United States
Cancer Centers of the Carolinas-W. Faris Road
Greenville, South Carolina, 29605, United States
Cancer Centers of the Carolinas (International)
Greenville, South Carolina, 29615, United States
Cancer Centers of the Carolinas - Seneca
Seneca, South Carolina, 29672, United States
Spartanburg Regional Healthcare System
Spartanburg, South Carolina, 29303, United States
Cancer Centers of the Carolinas - Spartanburg
Spartanburg, South Carolina, 29307, United States
Avera McKenna Hospital
Sioux Falls, South Dakota, 57101, United States
Avera Cancer Institute
Sioux Falls, South Dakota, 57105, United States
CCOP, Sanford Cancer Center - Oncology Clinic
Sioux Falls, South Dakota, 57105, United States
SCRI Chattanooga Oncol & Hematol Assoc, PC - Chattanooga
Chattanooga, Tennessee, 37404, United States
SCRI Tennessee Oncology - PLLC Franklin
Franklin, Tennessee, 37067, United States
SCRI Tennessee Oncology- Gallatin
Gallatin, Tennessee, 37066, United States
SCRI Tennessee Oncology, PLLC Hermitage
Hermitage, Tennessee, 37076, United States
SCRI Chattanooga Oncol & Hematol Assoc, PC Hixson
Hixson, Tennessee, 37404, United States
CCOP Holston Valley Medical Center
Kingsport, Tennessee, 37662, United States
SCRI Tennessee Oncology Lebanon
Lebanon, Tennessee, 37087, United States
SCRI Tennessee Oncology Murfreesboro
Murfreesboro, Tennessee, 37130, United States
SCRI - Tennessee Oncology PLLC
Nashville, Tennessee, 37203, United States
SCRI Tennessee Oncology, PLLC (Harding)
Nashville, Tennessee, 37205, United States
SCRI Tennessee Onclogy, PLLC (Dickerson)
Nashville, Tennessee, 37207, United States
SCRI - Tennessee Oncology PLLC
Nashville, Tennessee, 37211, United States
SCRI Tennessee Oncology, PLLC (Wallace)
Nashville, Tennessee, 37211, United States
Tennessee Oncology
Shelbyville, Tennessee, 37160, United States
SCRI Tennessee Oncology, PLLC Smyrna
Smyrna, Tennessee, 37167, United States
Texas Cancer Center - Abilene South
Abilene, Texas, 79606-5208, United States
Texas Oncology PA - Amarillo
Amarillo, Texas, 79106, United States
Texas Oncology PA - Arlington North
Arlington, Texas, 76012, United States
Texas Onclogy - Arlington South
Arlington, Texas, 76014, United States
Texas Oncology Central Austin
Austin, Texas, 78705, United States
Texas Oncology Cancer Center - Balcones
Austin, Texas, 78731, United States
South Austin Cancer Center
Austin, Texas, 78745, United States
Southwest Regional Cancer Center- North
Austin, Texas, 78759, United States
Texas Oncology North Austin- Renfert
Austin, Texas, 78759, United States
Mamie McFaddin Ward Cancer Center
Beaumont, Texas, 77702-1449, United States
Edwards Cancer Center - Bedford
Bedford, Texas, 76022, United States
Texas Oncology PA - Harris HEB
Bedford, Texas, 76022, United States
Texas Oncology, PA - Cedar Park
Cedar Park, Texas, 78613, United States
Texas Cancer Center at Medical City
Dallas, Texas, 75230-2510, United States
Texas Oncology PA- Presbyterian
Dallas, Texas, 75231-4400, United States
Methodist Charlton Cancer Center
Dallas, Texas, 75237, United States
Texas Oncology- Sammons CC
Dallas, Texas, 75246, United States
Texas Cancer Center
Denton, Texas, 76210, United States
El Paso Cancer Treatment Center - West
El Paso, Texas, 79902, United States
El Paso Cancer Treatment Center - East
El Paso, Texas, 79915, United States
Texas Oncology - 8th Avenue
Fort Worth, Texas, 76104, United States
Texas Oncology at Klabzuba
Fort Worth, Texas, 76104, United States
Texas Oncology PA - 12th Avenue
Fort Worth, Texas, 76104, United States
Southwest Fort Worth Cancer Center
Fort Worth, Texas, 76132, United States
San Antonio Tumor and Blood Clinic
Fredericksburg, Texas, 78624, United States
Texas Oncology PA
Garland, Texas, 75042-5788, United States
Texas Oncology
Grapevine, Texas, 76051, United States
Texas Oncology PA - Frostwood
Houston, Texas, 77024, United States
MD Anderson Cancer Center
Houston, Texas, 77030, United States
San Antonio Tumor and Blood Clinic
Kerrville, Texas, 78028, United States
Lake Vista Cancer Center
Lewisville, Texas, 75067, United States
Longview Cancer Center
Longview, Texas, 75601, United States
Joe Arrington Cancer Research & Treatment Center
Lubbock, Texas, 79410, United States
South Texas Cancer Center - McAllen
McAllen, Texas, 78503, United States
Texas Cancer Center of Mesquite
Mesquite, Texas, 75150, United States
Allison Cancer Center
Midland, Texas, 79701, United States
HOAST - New Braunfels
New Braunfels, Texas, 78130, United States
Texas Oncology - Odessa
Odessa, Texas, 79761, United States
Paris Regional Cancer Center
Paris, Texas, 75460-5004, United States
North Texas Regional Cancer Center
Plano, Texas, 75075, United States
Texas Oncology Plano West Cancer Center
Plano, Texas, 75093, United States
Texas Oncology Seton Williamson
Round Rock, Texas, 78665, United States
Texas Oncology - Round Rock Cancer Center
Round Rock, Texas, 78681, United States
Cancer Care Centers of South Texas- Brooklyn
San Antonio, Texas, 78212, United States
Cancer Care Centers of South Texas - Loop 410
San Antonio, Texas, 78217, United States
HOAST - Medical Drive
San Antonio, Texas, 78229, United States
San Antonio Tumor and Blood Clinic - M.Oak
San Antonio, Texas, 78258-3912, United States
University of Texas Health Science Center
San Antonio, Texas, 78284-7842, United States
Texas Oncology - San Marcos
San Marcos, Texas, 78666, United States
Texas Cancer Center
Sherman, Texas, 75090-0504, United States
Texas Oncology Cancer Center - Sugar Land
Sugar Land, Texas, 77479, United States
US Oncology
The Woodlands, Texas, 77380, United States
Tyler Cancer Center
Tyler, Texas, 75702, United States
Texas Oncology Cancer Care and Research Center
Waco, Texas, 76712, United States
Texas Oncology - Clear Lake
Webster, Texas, 77598, United States
South Texas Cancer Clinic
Weslaco, Texas, 78596, United States
Texoma Cancer Center
Wichita Falls, Texas, 76310, United States
Sandra L. Maxwell Cancer Center
Cedar City, Utah, 84720, United States
McKay-Dee Hospital Center
Ogden, Utah, 84403, United States
Utah Valley Regional Medical Center - Provo
Provo, Utah, 84604, United States
Huntsman Cancer Inst. at the University of Utah- Salt Lake City
Salt Lake City, Utah, 84132, United States
LDS Hospital
Salt Lake City, Utah, 84143, United States
Dixie Regional Medical Center - East Campus
St. George, Utah, 84770, United States
Southwestern Regional Cancer Center (SWORD)
Bennington, Vermont, 05201, United States
Arlington Fairfax Hematology Oncology
Arlington, Virginia, 22205, United States
Virginia Oncology Associates - Medical Pkwy
Chesapeake, Virginia, 23320, United States
Oncology and Hematology Associates of SW VA, Inc
Christiansburg, Virginia, 24073, United States
Fairfax Northern VA Hematology-Oncology PC
Fairfax, Virginia, 22031, United States
Fair Oaks Office
Fairfax, Virginia, 22033, United States
Fairfax-Northern Virginia Hematology-Oncology PC
Gainesville, Virginia, 20155, United States
Virginia Oncology Associates
Hampton, Virginia, 23606, United States
Fairfax-Northern Virginia Hematology-Oncology PC
Leesburg, Virginia, 20176, United States
SCRI Virginia Cancer Institute (Flank)
Mechanicsville, Virginia, 23116, United States
SCRI Virginia Cancer Institute
Midlothian, Virginia, 23114, United States
Virginia Oncology Associates
Newport News, Virginia, 23606, United States
Virginia Oncology Associates - Lake Wright
Norfolk, Virginia, 23502, United States
SCRI Virginia Cancer Institute (6605)
Richmond, Virginia, 23226, United States
SCRI Virginia Cancer Institute (1401)
Richmond, Virginia, 23235, United States
MBCCOP, Virginia Commonwealth University
Richmond, Virginia, 23298, United States
Oncology and Hematology Associates of SW VA, Inc
Roanoke, Virginia, 24014, United States
Oncology and Hematology Associates of SW VA, Inc
Salem, Virginia, 24153, United States
Virginia Oncology Associates
Virginia Beach, Virginia, 23456, United States
Virginia Oncology Associates
Williamsburg, Virginia, 23188, United States
Fairfax Northern Virginia Hematology-Oncology - Winchester
Winchester, Virginia, 22601, United States
Fairfax-Northern Virginia Hematology-Oncology PC
Woodbridge, Virginia, 22191, United States
Oncology and Hematology Associates of SW VA, Inc
Wytheville, Virginia, 24382, United States
Highline Medical Oncology
Burien, Washington, 98166, United States
Puget Sound Cancer Center- Edmonds
Edmonds, Washington, 98026, United States
Columbia Basin Hematology and Oncology
Kennewick, Washington, 99336, United States
Fred Hutchinson Cancer Research Center
Seattle, Washington, 98109-1024, United States
Puget Sound Cancer Center - Seattle
Seattle, Washington, 98133, United States
Cancer Care Northwest-South
Spokane, Washington, 99202, United States
Rockwood Clinic Cancer Treatment Center
Spokane, Washington, 99204-2967, United States
Cancer Care Northwest-Radiation Therapy (XRT)
Spokane, Washington, 99204, United States
Cancer Care Northwest- Valley - Mission
Spokane, Washington, 99216, United States
Cancer Care Northwest-North - Holland
Spokane, Washington, 99218, United States
Evergreen Hematology & Oncology (Farwell)
Spokane, Washington, 99218, United States
Northwest Cancer Specialists-136th Ave
Vancouver, Washington, 98684, United States
Northwest Cancer Specialists-134th St.
Vancouver, Washington, 98686, United States
Yakima Valley Memorial Hospital - North Star Lodge
Yakima, Washington, 98902, United States
Raleigh Regional Cancer Center
Beckley, West Virginia, 25801, United States
CAMC Health Education & Research Institute, Inc.
Charleston, West Virginia, 25304, United States
West Virginia University Hospitals Inc.
Morgantown, West Virginia, 26506-9162, United States
Camden-Clark Memorial Hospital
Parkersburg, West Virginia, 26101, United States
Wheeling Hospital
Wheeling, West Virginia, 26003, United States
Marshfield Clinic Chippewa Falls Center
Chippewa Falls, Wisconsin, 54729, United States
Marshfield Clinic Regional CA Cntr - Sacred Heart Hospital
Eau Claire, Wisconsin, 54701, United States
CCOP, St. Vincent Hospital
Green Bay, Wisconsin, 54301, United States
CCOP, St. Mary's Hospital Medical Center
Green Bay, Wisconsin, 54303, United States
CCOP - Marshfield Clinic Research Foundation
Marshfield, Wisconsin, 54449, United States
Aurora Sinai Medical Center
Milwaukee, Wisconsin, 53201-0342, United States
Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
Marshfield Clinic Minocqua Center
Minocqua, Wisconsin, 54548, United States
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904, United States
Marshfield Clinic at James Beck Cancer Center
Rhinelander, Wisconsin, 54501, United States
Marshfield Clinic Rice Lake Center
Rice Lake, Wisconsin, 54868, United States
Marshfield Clinic Cancer Care at St. Michael's Hospital
Stevens Point, Wisconsin, 54481, United States
Aspirus Regional Cancer Center
Wausau, Wisconsin, 54401, United States
Aurora Women's Pavilion of Aurora West Allis Medical Center
West Allis, Wisconsin, 53227, United States
CCOP Marshfield Clinic - Weston Center
Weston, Wisconsin, 54476, United States
Marshfield Clinic Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, 54494, United States
Bon Secours Hospital
Cork, CK, Ireland
Letterkenny General Hospital
Letterkenny, DL, Ireland
Mater Private Hospital
Dublin, DN, 7, Ireland
Beaumont Hospital
Dublin, 9, Ireland
St. Vincent's University Hospital
Dublin, DN4, Ireland
Mater Misericordiae
Dublin, DN7, Ireland
St James' Hospital
Dublin, DN8, Ireland
St. James' Hospital
Dublin, DN8, Ireland
University College Hospital
Galway, GY, Ireland
Sligo General Hospital
Sligo, CO Sligo, Ireland
Waterford Regional Hospital
Waterford, 0009, Ireland
Related Publications (1)
Geyer CE Jr, Blum JL, Yothers G, Asmar L, Flynn PJ, Robert NJ, Hopkins JO, O'Shaughnessy JA, Rastogi P, Puhalla SL, Hilton CJ, Dang CT, Gomez HL, Vukelja SJ, Lyss AP, Paul D, Brufsky AM, Colangelo LH, Swain SM, Mamounas EP, Wolmark N. Long-Term Follow-Up of the Anthracyclines in Early Breast Cancer Trials (USOR 06-090, NSABP B-46-I/USOR 07132, and NSABP B-49 [NRG Oncology]). J Clin Oncol. 2024 Apr 20;42(12):1344-1349. doi: 10.1200/JCO.23.01428. Epub 2024 Feb 9.
PMID: 38335467DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Norman Wolmark, MD
NSABP Foundation Inc
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- NETWORK
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 23, 2009
First Posted
April 24, 2009
Study Start
May 1, 2009
Primary Completion
February 1, 2018
Study Completion
February 1, 2018
Last Updated
April 20, 2022
Record last verified: 2022-04