Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

16.7%

15 terminated/withdrawn out of 90 trials

Success Rate

77.3%

-9.2% vs industry average

Late-Stage Pipeline

50%

45 trials in Phase 3/4

Results Transparency

69%

35 of 51 completed trials have results

Key Signals

2 recruiting35 with results10 terminated5 withdrawn

Enrollment Performance

Analytics

Phase 3
45(57.7%)
Phase 2
25(32.1%)
N/A
4(5.1%)
Phase 1
4(5.1%)
78Total
Phase 3(45)
Phase 2(25)
N/A(4)
Phase 1(4)

Activity Timeline

Global Presence

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Clinical Trials (90)

Showing 20 of 90 trials
NCT05633654Phase 3Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

Role: collaborator

NCT00310180Phase 3Active Not Recruiting

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Role: collaborator

NCT03155997Phase 3Active Not Recruiting

Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer

Role: collaborator

NCT02513394Phase 3Active Not Recruiting

PALbociclib CoLlaborative Adjuvant Study

Role: collaborator

NCT00066690Phase 3Completed

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Role: collaborator

NCT06401421Recruiting

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

Role: collaborator

NCT05210283Active Not Recruiting

CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer

Role: collaborator

NCT01772472Phase 3Completed

A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Role: collaborator

NCT07058012Phase 2Not Yet Recruiting

A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)

Role: lead

NCT04622319Phase 3Active Not Recruiting

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Role: collaborator

NCT03281954Phase 3Active Not Recruiting

Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo

Role: lead

NCT00382070Phase 3Active Not Recruiting

Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer

Role: lead

NCT00003782Phase 3Completed

Combination Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA (cT1-3, N0-1, M0) Breast Cancer and Positive Axillary Lymph Nodes

Role: lead

NCT00321828Phase 2Completed

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery

Role: lead

NCT01872975Not ApplicableActive Not Recruiting

Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery

Role: lead

NCT01864746Phase 3Completed

A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery

Role: collaborator

NCT00005957Not ApplicableCompleted

Radiation Therapy in Treating Women Who Have Undergone Surgery for Early-Stage Invasive Breast Cancer

Role: collaborator

NCT01011478Phase 3Terminated

Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By Surgery

Role: lead

NCT00002525Phase 3Terminated

Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed

Role: collaborator

NCT00028990Phase 3Completed

Paclitaxel With or Without Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

Role: collaborator