Success Metrics

Clinical Success Rate
81.1%

Based on 869 completed trials

Completion Rate
81%(869/1072)
Active Trials
339(20%)
Results Posted
69%(597 trials)
Terminated
203(12%)

Phase Distribution

Ph phase_2
922
54%
Ph phase_1
393
23%
Ph early_phase_1
19
1%
Ph not_applicable
46
3%
Ph phase_3
233
14%
Ph phase_4
46
3%

Phase Distribution

412

Early Stage

922

Mid Stage

279

Late Stage

Phase Distribution1659 total trials
Early Phase 1First-in-human
19(1.1%)
Phase 1Safety & dosage
393(23.7%)
Phase 2Efficacy & side effects
922(55.6%)
Phase 3Large-scale testing
233(14.0%)
Phase 4Post-market surveillance
46(2.8%)
N/ANon-phased studies
46(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.5%

869 of 1136 finished

Non-Completion Rate

23.5%

267 ended early

Currently Active

339

trials recruiting

Total Trials

1,712

all time

Status Distribution
Active(402)
Completed(869)
Terminated(267)
Other(174)

Detailed Status

Completed869
Recruiting220
Terminated203
unknown171
Active, not recruiting119
Withdrawn64

Development Timeline

Analytics

Development Status

Total Trials
1712
Active
339
Success Rate
81.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 119 (1.1%)
Phase 1393 (23.7%)
Phase 2922 (55.6%)
Phase 3233 (14.0%)
Phase 446 (2.8%)
N/A46 (2.8%)

Trials by Status

recruiting22013%
not_yet_recruiting583%
terminated20312%
suspended30%
completed86951%
unknown17110%
withdrawn644%
enrolling_by_invitation50%
active_not_recruiting1197%

Recent Activity

Clinical Trials (1,712)

Showing 20 of 1,712 trialsScroll for more
NCT05398861Phase 2

Utidelone Combined With Bevacizumab in the Treatment of ≥ 2 Lines of HER-2 Negative Advanced Breast Cancer

Recruiting
NCT07284849Phase 3

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Recruiting
NCT07318558Phase 3

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Recruiting
NCT07490262Phase 2

A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.

Recruiting
NCT06824467Phase 3

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Recruiting
NCT01187199Phase 1

Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

Active Not Recruiting
NCT06576037Phase 1

Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin

Recruiting
NCT06117891

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

Recruiting
NCT03451370

First-line Combination of Capecitabine and Oxaliplatin Plus Bevacizumab in Elderly Patients With Metastatic Colorectal Cancer

Active Not Recruiting
NCT06233942Phase 1

Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors

Recruiting
NCT03175432Phase 2

Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases

Active Not Recruiting
NCT05039801Phase 1

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Recruiting
NCT05001880Phase 2

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Recruiting
NCT06427941Phase 1

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

Recruiting
NCT07288034Phase 2

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

Recruiting
NCT03778957Phase 3

A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma

Active Not Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT03786081Phase 1

Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer

Terminated
NCT07291076Phase 1

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

Recruiting
NCT05238922Phase 1

Study of INCB123667 in Subjects With Advanced Solid Tumors

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,712