Success Metrics

Clinical Success Rate
80.8%

Based on 872 completed trials

Completion Rate
81%(872/1079)
Active Trials
348(20%)
Results Posted
69%(604 trials)
Terminated
207(12%)

Phase Distribution

Ph phase_1
397
23%
Ph phase_3
236
14%
Ph phase_4
47
3%
Ph early_phase_1
19
1%
Ph not_applicable
47
3%
Ph phase_2
928
54%

Phase Distribution

416

Early Stage

928

Mid Stage

283

Late Stage

Phase Distribution1674 total trials
Early Phase 1First-in-human
19(1.1%)
Phase 1Safety & dosage
397(23.7%)
Phase 2Efficacy & side effects
928(55.4%)
Phase 3Large-scale testing
236(14.1%)
Phase 4Post-market surveillance
47(2.8%)
N/ANon-phased studies
47(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.2%

872 of 1145 finished

Non-Completion Rate

23.8%

273 ended early

Currently Active

348

trials recruiting

Total Trials

1,727

all time

Status Distribution
Active(412)
Completed(872)
Terminated(273)
Other(170)

Detailed Status

Completed872
Recruiting229
Terminated207
unknown168
Active, not recruiting119
Withdrawn66

Development Timeline

Analytics

Development Status

Total Trials
1727
Active
348
Success Rate
80.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 119 (1.1%)
Phase 1397 (23.7%)
Phase 2928 (55.4%)
Phase 3236 (14.1%)
Phase 447 (2.8%)
N/A47 (2.8%)

Trials by Status

completed87250%
enrolling_by_invitation50%
recruiting22913%
not_yet_recruiting593%
active_not_recruiting1197%
suspended20%
unknown16810%
withdrawn664%
terminated20712%

Recent Activity

Clinical Trials (1,727)

Showing 20 of 1,727 trialsScroll for more
NCT07198074Phase 3

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT05862285Phase 3

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Recruiting
NCT06843447Phase 1

A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

Recruiting
NCT07527858Phase 2

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer

Recruiting
NCT07318558Phase 3

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Recruiting
NCT07216703Phase 3

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

Recruiting
NCT06824467Phase 3

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Recruiting
NCT04181060Phase 3

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting
NCT01445509Phase 1

Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors

Completed
NCT05647122Phase 1

First in Human Study of AZD9592 in Solid Tumors

Active Not Recruiting
NCT07318389Early Phase 1

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

Not Yet Recruiting
NCT06921785Phase 3

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

Recruiting
NCT04607421Phase 3

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting
NCT07642960Not Applicable

Fine-needle Diathermy Combined With Subconjunctival Bevacizumab for Corneal Neovascularization

Recruiting
NCT04587128Phase 2

Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC

Active Not Recruiting
NCT05083481Phase 1

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Terminated
NCT07637851Phase 1

Safety and Efficacy of Ubamatamab With First-line Chemotherapy in Ovarian Cancer

Not Yet Recruiting
NCT06986785Phase 2

A Study of BL-B01D1 Monotherapy, BL-B01D1 in Combination With Lenvatinib, BL-B01D1 in Combination With PD-1 Monoclonal Antibody, and BL-B01D1 in Combination With PD-1 Monoclonal Antibody and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma

Recruiting
NCT07059845Phase 2

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
1,727