Success Metrics

Clinical Success Rate
78.7%

Based on 1,371 completed trials

Completion Rate
79%(1371/1742)
Active Trials
691(23%)
Results Posted
64%(874 trials)
Terminated
371(13%)

Phase Distribution

Ph phase_4
42
1%
Ph phase_1
957
32%
Ph early_phase_1
47
2%
Ph not_applicable
101
3%
Ph phase_2
1,307
44%
Ph phase_3
471
16%

Phase Distribution

1004

Early Stage

1307

Mid Stage

513

Late Stage

Phase Distribution2925 total trials
Early Phase 1First-in-human
47(1.6%)
Phase 1Safety & dosage
957(32.7%)
Phase 2Efficacy & side effects
1,307(44.7%)
Phase 3Large-scale testing
471(16.1%)
Phase 4Post-market surveillance
42(1.4%)
N/ANon-phased studies
101(3.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.3%

1371 of 1870 finished

Non-Completion Rate

26.7%

499 ended early

Currently Active

691

trials recruiting

Total Trials

2,958

all time

Status Distribution
Active(767)
Completed(1371)
Terminated(499)
Other(321)

Detailed Status

Completed1371
Recruiting410
Terminated371
unknown305
Active, not recruiting281
Withdrawn128

Development Timeline

Analytics

Development Status

Total Trials
2958
Active
691
Success Rate
78.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 147 (1.6%)
Phase 1957 (32.7%)
Phase 21307 (44.7%)
Phase 3471 (16.1%)
Phase 442 (1.4%)
N/A101 (3.5%)

Trials by Status

active_not_recruiting2819%
completed137146%
recruiting41014%
enrolling_by_invitation50%
unknown30510%
not_yet_recruiting712%
suspended161%
terminated37113%
withdrawn1284%

Recent Activity

Clinical Trials (2,958)

Showing 20 of 2,958 trialsScroll for more
NCT07509034Phase 1

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Not Yet Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT07223021Phase 3

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

Recruiting
NCT07572136Phase 1

Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Not Yet Recruiting
NCT06058377Phase 3

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Recruiting
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT06383572Phase 1

Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies

Recruiting
NCT07321912Phase 2

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Recruiting
NCT06904066Phase 1

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT07328503Phase 2

CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Recruiting
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT05673785Phase 2

A Study of Brentuximab Vedotin in Combination With Cyclophosphamide, Doxorubicin (Hydroxydaunorubicin), Prednisone (CHP) in Chinese Participants With CD30-Positive (CD30+) Peripheral T-Cell Lymphomas (PTCL)

Active Not Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT04959175Phase 1

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Recruiting
NCT07641049Phase 1

Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer

Recruiting
NCT07641036Phase 1

Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer

Recruiting
NCT07643103Phase 2

Immuno-Targeted Therapy Plus Low-Dose Chemotherapy for Newly Diagnosed Adult Ph-Negative B-ALL: A Prospective Umbrella Trial

Not Yet Recruiting
NCT07220187Phase 3

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

Not Yet Recruiting
NCT01174121Phase 2

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
2,958