Success Metrics

Clinical Success Rate
75.6%

Based on 266 completed trials

Completion Rate
76%(266/352)
Active Trials
196(30%)
Results Posted
89%(236 trials)
Terminated
86(13%)

Phase Distribution

Ph phase_2
317
48%
Ph phase_4
11
2%
Ph not_applicable
15
2%
Ph phase_1
151
23%
Ph early_phase_1
7
1%
Ph phase_3
147
22%

Phase Distribution

158

Early Stage

317

Mid Stage

158

Late Stage

Phase Distribution648 total trials
Early Phase 1First-in-human
7(1.1%)
Phase 1Safety & dosage
151(23.3%)
Phase 2Efficacy & side effects
317(48.9%)
Phase 3Large-scale testing
147(22.7%)
Phase 4Post-market surveillance
11(1.7%)
N/ANon-phased studies
15(2.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.4%

266 of 378 finished

Non-Completion Rate

29.6%

112 ended early

Currently Active

196

trials recruiting

Total Trials

661

all time

Status Distribution
Active(217)
Completed(266)
Terminated(112)
Other(66)

Detailed Status

Completed266
Recruiting116
Terminated86
Active, not recruiting80
unknown64
Withdrawn26

Development Timeline

Analytics

Development Status

Total Trials
661
Active
196
Success Rate
75.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (1.1%)
Phase 1151 (23.3%)
Phase 2317 (48.9%)
Phase 3147 (22.7%)
Phase 411 (1.7%)
N/A15 (2.3%)

Trials by Status

not_yet_recruiting193%
completed26640%
enrolling_by_invitation20%
terminated8613%
unknown6410%
active_not_recruiting8012%
recruiting11618%
suspended20%
withdrawn264%

Recent Activity

Clinical Trials (661)

Showing 20 of 661 trialsScroll for more
NCT06717347Phase 3

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Recruiting
NCT07224100Phase 2

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
NCT00479128Phase 1

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

Active Not Recruiting
NCT01857934Phase 2

Therapy for Children With Advanced Stage Neuroblastoma

Completed
NCT06058377Phase 3

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT05605899Phase 3

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma

Active Not Recruiting
NCT01424982Phase 2

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT04847063Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT04216524Phase 2

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

Recruiting
NCT00092222Phase 2

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

Active Not Recruiting
NCT06422806Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT06564038Phase 1

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

Recruiting
NCT02180867Phase 2

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Active Not Recruiting
NCT02306161Phase 3

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Active Not Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT05099666Phase 1

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Active Not Recruiting
NCT06191744Phase 3

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
661