Success Metrics

Clinical Success Rate
75.9%

Based on 271 completed trials

Completion Rate
76%(271/357)
Active Trials
194(29%)
Results Posted
88%(238 trials)
Terminated
86(13%)

Phase Distribution

Ph phase_3
147
22%
Ph not_applicable
15
2%
Ph phase_2
319
48%
Ph phase_1
152
23%
Ph early_phase_1
7
1%
Ph phase_4
11
2%

Phase Distribution

159

Early Stage

319

Mid Stage

158

Late Stage

Phase Distribution651 total trials
Early Phase 1First-in-human
7(1.1%)
Phase 1Safety & dosage
152(23.3%)
Phase 2Efficacy & side effects
319(49.0%)
Phase 3Large-scale testing
147(22.6%)
Phase 4Post-market surveillance
11(1.7%)
N/ANon-phased studies
15(2.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.8%

271 of 383 finished

Non-Completion Rate

29.2%

112 ended early

Currently Active

194

trials recruiting

Total Trials

664

all time

Status Distribution
Active(216)
Completed(271)
Terminated(112)
Other(65)

Detailed Status

Completed271
Recruiting111
Terminated86
Active, not recruiting83
unknown64
Withdrawn26

Development Timeline

Analytics

Development Status

Total Trials
664
Active
194
Success Rate
75.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (1.1%)
Phase 1152 (23.3%)
Phase 2319 (49.0%)
Phase 3147 (22.6%)
Phase 411 (1.7%)
N/A15 (2.3%)

Trials by Status

completed27141%
active_not_recruiting8313%
unknown6410%
enrolling_by_invitation20%
withdrawn264%
suspended10%
not_yet_recruiting203%
recruiting11117%
terminated8613%

Recent Activity

Clinical Trials (664)

Showing 20 of 664 trialsScroll for more
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT07321912Phase 2

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Recruiting
NCT05673785Phase 2

A Study of Brentuximab Vedotin in Combination With Cyclophosphamide, Doxorubicin (Hydroxydaunorubicin), Prednisone (CHP) in Chinese Participants With CD30-Positive (CD30+) Peripheral T-Cell Lymphomas (PTCL)

Active Not Recruiting
NCT06058377Phase 3

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Recruiting
NCT06960577Phase 3

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT06422806Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Recruiting
NCT07044336Phase 3

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

Recruiting
NCT06564038Phase 1

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

Recruiting
NCT03719430Phase 2

APX005M and Doxorubicin in Advanced Sarcoma

Completed
NCT07638787Phase 1

Pola-R-CHP Plus Sonrotoclax in Untreated BCL2-High/Double-Hit LBCL

Not Yet Recruiting
NCT06239272Phase 1

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Recruiting
NCT07636564Phase 2

Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

Not Yet Recruiting
NCT05113251Phase 3

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Active Not Recruiting
NCT04884035Phase 1

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Recruiting
NCT06890884Phase 2

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Recruiting
NCT06717347Phase 3

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Recruiting
NCT06284122Phase 3

Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy in Follicular Lymphoma FLIPI2-5

Recruiting
NCT07278856Phase 1

Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
664