Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

17.5%

283 terminated/withdrawn out of 1617 trials

Success Rate

78.8%

-7.8% vs industry average

Late-Stage Pipeline

13%

205 trials in Phase 3/4

Results Transparency

68%

713 of 1049 completed trials have results

Key Signals

111 recruiting713 with results216 terminated67 withdrawn

Enrollment Performance

Analytics

Phase 2
713(47.7%)
Phase 1
509(34.0%)
Phase 3
127(8.5%)
Phase 4
78(5.2%)
N/A
47(3.1%)
Early Phase 1
22(1.5%)
1496Total
Phase 2(713)
Phase 1(509)
Phase 3(127)
Phase 4(78)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (1617)

Showing 20 of 1617 trials
NCT05376319Phase 2Terminated

PR3-AAV Resilient Remission or PRRR

Role: collaborator

NCT04401748Phase 3Active Not Recruiting

Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

Role: collaborator

NCT06603246Phase 1Recruiting

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

Role: lead

NCT05681039Phase 2Recruiting

Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).

Role: collaborator

NCT07567846Phase 1Not Yet Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

Role: lead

NCT06619587Phase 1Recruiting

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Role: lead

NCT06979336Phase 2Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Role: lead

NCT00584935Phase 1Completed

Clinical Trial Evaluating Rituximab in Ocular Cicatricial Pemphigoid

Role: collaborator

NCT07214662Phase 1Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination With Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer

Role: lead

NCT06096779Phase 2Recruiting

A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

Role: lead

NCT04434040Phase 2Recruiting

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

Role: collaborator

NCT05039619Phase 2Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Role: collaborator

NCT03563716Phase 2Completed

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Role: lead

NCT05927571Phase 1Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Role: lead

NCT06031441Phase 1Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Role: lead

NCT00603629Completed

Mechanisms of Acute Asthma Exacerbations Through Molecular Analysis of Airway Secretions and Tissues

Role: collaborator

NCT07558915Phase 1Not Yet Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of RO7851624 in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Role: lead

NCT06696131Phase 1Not Yet Recruiting

Tenecteplase (TNK) in the Treatment of Intracerebral Hemorrhage (ICH)

Role: collaborator

NCT07214766Phase 1Recruiting

A Study to Assess the Bioequivalence of Trastuzumab Via Different Subcutaneous Delivery Platforms in Healthy Male Participants

Role: lead

NCT06765317Phase 2Recruiting

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Role: collaborator