Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

17.7%

291 terminated/withdrawn out of 1645 trials

Success Rate

78.6%

-8.0% vs industry average

Late-Stage Pipeline

13%

208 trials in Phase 3/4

Results Transparency

68%

728 of 1069 completed trials have results

Key Signals

103 recruiting728 with results222 terminated69 withdrawn

Enrollment reporting

Analytics

Phase 2
696(45.8%)
Phase 1
393(25.9%)
Phase 1/2
132(8.7%)
Phase 3
127(8.4%)
Phase 4
81(5.3%)
N/A
47(3.1%)
Early Phase 1
22(1.4%)
Phase 2/3
21(1.4%)
1519Total
Phase 2(696)
Phase 1(393)
Phase 1/2(132)
Phase 3(127)
+4 more

Activity Timeline

Global Presence

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Clinical Trials (1645)

Showing 20 of 1645 trials
NCT03994796Phase 2Active Not Recruiting

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Role: collaborator

NCT06765317Phase 2Recruiting

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Role: collaborator

NCT07609719Phase 4Recruiting

A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy

Role: lead

NCT05410418Phase 2Active Not Recruiting

Mosunetuzumab and Polatuzumab Vedotin for Untreated Follicular Lymphoma

Role: collaborator

NCT06979336Phase 2Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Role: lead

NCT02989584Phase 1/2Active Not Recruiting

A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer

Role: collaborator

NCT04079179Phase 2Recruiting

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Role: collaborator

NCT04409639Phase 2Active Not Recruiting

Cobimetinib in Newly Diagnosed or HMA-treated CMML Patients With RAS Pathway Mutations

Role: collaborator

NCT07100106Phase 1/2Recruiting

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

Role: lead

NCT07851259Phase 2Recruiting

A Study to Assess the Efficacy and Safety of RO7965032 in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Role: lead

NCT05844982Phase 3Recruiting

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

Role: collaborator

NCT06619587Phase 1Recruiting

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Role: lead

NCT07024706Phase 2Recruiting

MAVRiC Studies 2L Treatment With AV in Patients With CLL/SLL Who Have Relapsed After a Course of BTKi + BCL2i Combination, With or Without Obinutuzumab

Role: collaborator

NCT07144111Phase 1Completed

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

Role: lead

NCT03709758Phase 1Active Not Recruiting

Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AML

Role: collaborator

NCT04262154Phase 2Active Not Recruiting

Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer

Role: collaborator

NCT05232929Phase 4Completed

Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

Role: lead

NCT07643831Unknown

Expanded Access Program to Provide Giredestrant to Participants With ER+, HER2- Early or Locally Advanced/Metastatic Breast Cancer

Role: lead

NCT06043674Phase 2Recruiting

Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

Role: collaborator

NCT01937117Phase 2Active Not Recruiting

Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer

Role: collaborator