Success Metrics

Clinical Success Rate
78.5%

Based on 850 completed trials

Completion Rate
78%(850/1083)
Active Trials
275(17%)
Results Posted
59%(498 trials)
Terminated
233(14%)

Phase Distribution

Ph phase_2
826
51%
Ph phase_1
367
23%
Ph phase_3
361
22%
Ph phase_4
17
1%
Ph not_applicable
27
2%
Ph early_phase_1
3
0%

Phase Distribution

370

Early Stage

826

Mid Stage

378

Late Stage

Phase Distribution1601 total trials
Early Phase 1First-in-human
3(0.2%)
Phase 1Safety & dosage
367(22.9%)
Phase 2Efficacy & side effects
826(51.6%)
Phase 3Large-scale testing
361(22.5%)
Phase 4Post-market surveillance
17(1.1%)
N/ANon-phased studies
27(1.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.4%

850 of 1128 finished

Non-Completion Rate

24.6%

278 ended early

Currently Active

275

trials recruiting

Total Trials

1,625

all time

Status Distribution
Active(315)
Completed(850)
Terminated(278)
Other(182)

Detailed Status

Completed850
Terminated233
unknown178
Recruiting153
Active, not recruiting122
Withdrawn45

Development Timeline

Analytics

Development Status

Total Trials
1625
Active
275
Success Rate
78.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (0.2%)
Phase 1367 (22.9%)
Phase 2826 (51.6%)
Phase 3361 (22.5%)
Phase 417 (1.1%)
N/A27 (1.7%)

Trials by Status

withdrawn453%
completed85052%
enrolling_by_invitation20%
recruiting1539%
unknown17811%
terminated23314%
active_not_recruiting1228%
not_yet_recruiting382%
suspended40%

Recent Activity

Clinical Trials (1,625)

Showing 20 of 1,625 trialsScroll for more
NCT05296798Phase 3

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Active Not Recruiting
NCT06780098Phase 2

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

Recruiting
NCT06931340Phase 3

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

Recruiting
NCT06472245Phase 3

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Recruiting
NCT03340896Phase 3

Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT

Active Not Recruiting
NCT07852195Phase 2

Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer

Not Yet Recruiting
NCT00588770Phase 3

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT06078709Phase 2

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT05541016Phase 2

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

Recruiting
NCT05176483Phase 1

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

Recruiting
NCT05063552Phase 2

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Active Not Recruiting
NCT07102381Phase 2

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

Recruiting
NCT07850973Phase 1

Phase 1/2 Study Of PARP Inhibition With Olaparib To Enhance The Efficacy Of High-Dose Chemotherapy In Refractory And Relapsed Germ Cell Tumors

Not Yet Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT03906071Phase 3

Phase 3 Study of Sitravatinib Plus Nivolumab vs Docetaxel in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer

Terminated
NCT03448835Phase 2

Neoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer (PANDA)

Active Not Recruiting
NCT02486718Phase 3

Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]

Completed
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT06764485Phase 3

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

Active Not Recruiting
NCT05378763Phase 3

A Study of Poziotinib in Previously Treated Participants With Locally Advanced or Metastatic NSCLC Harboring HER2 Exon 20 Mutations

Suspended

Drug Details

Intervention Type
DRUG
Total Trials
1,625