Success Metrics

Clinical Success Rate
82.2%

Based on 129 completed trials

Completion Rate
82%(129/157)
Active Trials
34(16%)
Results Posted
66%(85 trials)
Terminated
28(13%)

Phase Distribution

Ph phase_1
53
25%
Ph not_applicable
6
3%
Ph phase_3
35
17%
Ph phase_4
3
1%
Ph early_phase_1
1
0%
Ph phase_2
109
52%

Phase Distribution

54

Early Stage

109

Mid Stage

38

Late Stage

Phase Distribution207 total trials
Early Phase 1First-in-human
1(0.5%)
Phase 1Safety & dosage
53(25.6%)
Phase 2Efficacy & side effects
109(52.7%)
Phase 3Large-scale testing
35(16.9%)
Phase 4Post-market surveillance
3(1.4%)
N/ANon-phased studies
6(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.1%

129 of 159 finished

Non-Completion Rate

18.9%

30 ended early

Currently Active

34

trials recruiting

Total Trials

210

all time

Status Distribution
Active(37)
Completed(129)
Terminated(30)
Other(14)

Detailed Status

Completed129
Terminated28
Recruiting17
Active, not recruiting17
unknown14
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
210
Active
34
Success Rate
82.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.5%)
Phase 153 (25.6%)
Phase 2109 (52.7%)
Phase 335 (16.9%)
Phase 43 (1.4%)
N/A6 (2.9%)

Trials by Status

recruiting178%
terminated2813%
completed12961%
unknown147%
active_not_recruiting178%
withdrawn21%
not_yet_recruiting31%

Recent Activity

Clinical Trials (210)

Showing 20 of 210 trialsScroll for more
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT07278856Phase 1

Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas

Recruiting
NCT07059611Phase 2

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

Not Yet Recruiting
NCT07021989Phase 2

ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

Not Yet Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT01840566Phase 1

High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT04174742

Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer

Recruiting
NCT00334815Phase 2

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Active Not Recruiting
NCT05645718Phase 2

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Recruiting
NCT06528691Phase 2

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

Recruiting
NCT06738368Phase 2

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT06594939Phase 2

Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma

Not Yet Recruiting
NCT00433420Phase 3

Combination Chemotherapy With or Without Fluorouracil and/or Pegfilgrastim in Treating Women With Node-Positive Breast Cancer

Active Not Recruiting
NCT07224100Phase 2

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
NCT01624805Phase 2

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

Recruiting
NCT03609216Phase 2

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Active Not Recruiting
NCT03220022Phase 1

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Active Not Recruiting
NCT00066443Phase 1

Epirubicin, Docetaxel, and Pegfilgrastim in Treating Women With Locally Advanced or Inflammatory Breast Cancer

Completed

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
210