Success Metrics

Clinical Success Rate
82.2%

Based on 129 completed trials

Completion Rate
82%(129/157)
Active Trials
35(17%)
Results Posted
67%(86 trials)
Terminated
28(13%)

Phase Distribution

Ph phase_3
35
17%
Ph phase_1
53
25%
Ph early_phase_1
1
0%
Ph not_applicable
6
3%
Ph phase_2
109
52%
Ph phase_4
3
1%

Phase Distribution

54

Early Stage

109

Mid Stage

38

Late Stage

Phase Distribution207 total trials
Early Phase 1First-in-human
1(0.5%)
Phase 1Safety & dosage
53(25.6%)
Phase 2Efficacy & side effects
109(52.7%)
Phase 3Large-scale testing
35(16.9%)
Phase 4Post-market surveillance
3(1.4%)
N/ANon-phased studies
6(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.1%

129 of 159 finished

Non-Completion Rate

18.9%

30 ended early

Currently Active

35

trials recruiting

Total Trials

210

all time

Status Distribution
Active(36)
Completed(129)
Terminated(30)
Other(15)

Detailed Status

Completed129
Terminated28
Active, not recruiting18
Recruiting17
unknown14
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
210
Active
35
Success Rate
82.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.5%)
Phase 153 (25.6%)
Phase 2109 (52.7%)
Phase 335 (16.9%)
Phase 43 (1.4%)
N/A6 (2.9%)

Trials by Status

not_yet_recruiting10%
recruiting178%
terminated2813%
suspended10%
unknown147%
active_not_recruiting189%
withdrawn21%
completed12961%

Recent Activity

Clinical Trials (210)

Showing 20 of 210 trialsScroll for more
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT06738368Phase 2

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Suspended
NCT05645718Phase 2

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Recruiting
NCT06220032Phase 3

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma

Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT03214562Phase 1

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT05011188Phase 1

FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer

Active Not Recruiting
NCT05535166Phase 2

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Recruiting
NCT00070564Phase 3

S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer

Active Not Recruiting
NCT00334815Phase 2

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Active Not Recruiting
NCT06594939Phase 2

Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma

Recruiting
NCT07021989Phase 2

ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

Recruiting
NCT03147612Phase 2

Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03943901Phase 2

Split-Dose R-CHOP for Older Adults With DLBCL

Active Not Recruiting
NCT07224100Phase 2

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
NCT03220022Phase 1

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Active Not Recruiting
NCT03136146Phase 2

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia

Recruiting
NCT07064018Phase 1

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
210