Success Metrics

Clinical Success Rate
82.2%

Based on 129 completed trials

Completion Rate
82%(129/157)
Active Trials
33(16%)
Results Posted
66%(85 trials)
Terminated
28(13%)

Phase Distribution

Ph phase_3
35
17%
Ph early_phase_1
1
0%
Ph phase_1
53
25%
Ph phase_2
109
52%
Ph phase_4
3
1%
Ph not_applicable
6
3%

Phase Distribution

54

Early Stage

109

Mid Stage

38

Late Stage

Phase Distribution207 total trials
Early Phase 1First-in-human
1(0.5%)
Phase 1Safety & dosage
53(25.6%)
Phase 2Efficacy & side effects
109(52.7%)
Phase 3Large-scale testing
35(16.9%)
Phase 4Post-market surveillance
3(1.4%)
N/ANon-phased studies
6(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.1%

129 of 159 finished

Non-Completion Rate

18.9%

30 ended early

Currently Active

33

trials recruiting

Total Trials

210

all time

Status Distribution
Active(37)
Completed(129)
Terminated(30)
Other(14)

Detailed Status

Completed129
Terminated28
Active, not recruiting17
Recruiting16
unknown14
Not yet recruiting4

Development Timeline

Analytics

Development Status

Total Trials
210
Active
33
Success Rate
82.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.5%)
Phase 153 (25.6%)
Phase 2109 (52.7%)
Phase 335 (16.9%)
Phase 43 (1.4%)
N/A6 (2.9%)

Trials by Status

not_yet_recruiting42%
recruiting168%
completed12961%
unknown147%
active_not_recruiting178%
withdrawn21%
terminated2813%

Recent Activity

Clinical Trials (210)

Showing 20 of 210 trialsScroll for more
NCT07224100Phase 2

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
NCT01624805Phase 2

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

Recruiting
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT03220022Phase 1

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Active Not Recruiting
NCT03609216Phase 2

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Active Not Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT04759586Phase 3

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Active Not Recruiting
NCT06738368Phase 2

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Recruiting
NCT00066443Phase 1

Epirubicin, Docetaxel, and Pegfilgrastim in Treating Women With Locally Advanced or Inflammatory Breast Cancer

Completed
NCT06528691Phase 2

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

Recruiting
NCT07021989Phase 2

ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

Not Yet Recruiting
NCT03214562Phase 1

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT04684368Phase 2

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Recruiting
NCT06709495Phase 1

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

Recruiting
NCT03147612Phase 2

Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03136146Phase 2

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia

Recruiting
NCT03301350Phase 2

Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer

Completed
NCT05535166Phase 2

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Recruiting
NCT06594939Phase 2

Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma

Not Yet Recruiting
NCT04323956Phase 1

Parsaclisib Plus the Standard Drug Therapy in Patients With Newly Diagnosed, High Risk Diffuse Large B-cell Lymphoma

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
210