Research Impact

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Research impact score

Publications

0

Total publications

Trial Results

0

Published trial results

Citations

0

Total citations

Drug Portfolio

Analytics

Trial Phases

Phase 115
Phase 211

Trial Status

Completed1
Recruiting3
Terminated10
Other7

Role Distribution

Principal Investigator21
PI Rate100%

Activity Timeline

Clinical Trials (20)

NCT06654050Phase 2Withdrawn
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma
BRCA1-Associated Protein-1 (BAP1) MutationsEarly-stage BAP1-associated MalignanciesEarly-stage Mesothelioma+3 more
PrincipalinvestigatorStart date: 2026-03-16
NCT05375825Phase 1Withdrawn
Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin
Epithelial Tumors, MalignantMalignant Pleural Effusions (Mpe)Malignant Pleural Mesotheliomas (Mpm)+2 more
PrincipalinvestigatorStart date: 2024-01-31
NCT05960773Phase 2Recruiting
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma
BRCA1-Associated Protein-1 (BAP1) MutationsEarly-stage BAP1-associated MalignanciesEarly-stage Mesothelioma+3 more
PrincipalinvestigatorStart date: 2024-01-31
NCT04648826Phase 1/2Withdrawn
Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies
Epithelial Malignancies (Excluding Lung and Renal Cell Carcinomas)Germ Cell TumorsMelanomas+2 more
PrincipalinvestigatorStart date: 2021-12-14
NCT02054104Phase 1/2Terminated
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum
Cancers of Non-thoracic Origin With Metastases to the Lungs or PleuraMelanomaSarcoma+2 more
PrincipalinvestigatorStart date: 2014-09-03
NCT01624090Phase 2Terminated
Mithramycin for Lung, Esophagus, and Other Chest Cancers
Breast CancerEsophageal CancerGastrointestinal Neoplasms+2 more
PrincipalinvestigatorStart date: 2012-09-06

Showing 10 of 20 trials

Research Network

Collaboration Network

1 collaborators·0 connections
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Similar Key Opinion Leaders

Discover other key opinion leaders with similar research profiles, therapeutic areas, and collaboration networks.

10 similar investigators found

Steven A Rosenberg, M.D.

National Cancer Institute (NCI)

Related
32 trials

Shared therapeutic areas:

MelanomaMetastatic MelanomaBreast Cancer+4 more

Worked with same sponsors:

National Cancer Institute (NCI)
Similarity Score4%

Zhenfeng Zhang, MD, PhD

Second Affiliated Hospital of Guangzhou Medical University

Related
21 trials

Shared therapeutic areas:

Lung CancerBreast CancerCarcinoma, Non-Small-Cell Lung+3 more
Similarity Score3%

Dong-Xin Wang, MD, PhD

Peking University First Hospital

Related
74 trials

Shared therapeutic areas:

Lung CancerNeoplasmsBreast Cancer+2 more
Similarity Score3%

Lin Shen, MD

Peking University Cancer Hospital & Institute

Related
20 trials

Shared therapeutic areas:

Breast CancerLung CancerCancer of Esophagus+1 more
Similarity Score2%

Lizhi Niu, PhD

Fuda Cancer Hospital

Related
31 trials

Shared therapeutic areas:

Breast CancerLung CancerEsophageal Neoplasms
Similarity Score2%

Aminah Jatoi, MD

Mayo Clinic

Related
29 trials

Shared therapeutic areas:

Cancer of EsophagusLung CancerBreast Cancer

Worked with same sponsors:

National Cancer Institute (NCI)
Similarity Score2%

Rahul Aggarwal, MD

University of California, San Francisco

Related
22 trials

Shared therapeutic areas:

Metastatic MelanomaCarcinoma, Non-Small-Cell LungCarcinoma, Small Cell

Worked with same sponsors:

National Cancer Institute (NCI)
Similarity Score2%

Mark Levine, MD

Ontario Clinical Oncology Group (OCOG)

Related
13 trials

Shared therapeutic areas:

Breast CancerCancer of EsophagusCarcinoma, Non-Small-Cell Lung
Similarity Score2%

Sabine Hazan, MD

ProgenaBiome

Related
41 trials

Shared therapeutic areas:

MesotheliomaMesothelioma, Malignant
Similarity Score1%

You Lu, MD

West China Hospital

Related
18 trials

Shared therapeutic areas:

Carcinoma, Non-Small-Cell LungLung Cancer
Similarity Score1%

Publications (0)

No publications found for this investigator.

Clinical Trials (21)

Showing 20 of 21 trials

NCT06654050Phase 2PrincipalInvestigator

Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma

BRCA1-Associated Protein-1 (BAP1) MutationsEarly-stage BAP1-associated MalignanciesEarly-stage Mesothelioma+3 more
Withdrawn
NCT05898828Phase 1/2PrincipalInvestigator

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Esophageal Cancer (EsC)Esophageal NeoplasmsEsophagus Cancer+3 more
Withdrawn
NCT05375825Phase 1PrincipalInvestigator

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Epithelial Tumors, MalignantMalignant Pleural Effusions (Mpe)Malignant Pleural Mesotheliomas (Mpm)+2 more
Withdrawn
NCT05960773Phase 2PrincipalInvestigator

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

BRCA1-Associated Protein-1 (BAP1) MutationsEarly-stage BAP1-associated MalignanciesEarly-stage Mesothelioma+3 more
Recruiting
NCT04648826Phase 1/2PrincipalInvestigator

Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies

Epithelial Malignancies (Excluding Lung and Renal Cell Carcinomas)Germ Cell TumorsMelanomas+2 more
Withdrawn
NCT04431024PrincipalInvestigator

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

BRCA1-Associated Protein-1 (BAP1) MutationsFamilial CancerMesothelioma+1 more
Recruiting
NCT02859415Phase 1/2PrincipalInvestigator

Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases

Esophageal NeoplasmsLung NeoplasmsMesothelioma+2 more
Terminated
NCT03233724Phase 1/2PrincipalInvestigator

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Carcinoma, EsophagealCarcinoma, Non-Small-Cell LungLung Cancer+2 more
Terminated
NCT02054104Phase 1/2PrincipalInvestigator

Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

Cancers of Non-thoracic Origin With Metastases to the Lungs or PleuraMelanomaSarcoma+2 more
Terminated
NCT01624090Phase 2PrincipalInvestigator

Mithramycin for Lung, Esophagus, and Other Chest Cancers

Breast CancerEsophageal CancerGastrointestinal Neoplasms+2 more
Terminated
NCT01313429Phase 1PrincipalInvestigator

Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or Mediastinum

Epithelial MalignanciesMelanomaPleural Malignancies+1 more
Terminated
NCT01143545Phase 1PrincipalInvestigator

Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas

Esophageal CancerLung CancerMalignant Pleural Mesothelioma+2 more
Terminated
NCT00242723PrincipalInvestigator

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Cancers of Non Thoracic Origin With Metastases to the Lungs or PleuraEsophageal Cancers NOSLung Cancer NOS+3 more
Recruiting
NCT00037817Phase 1PrincipalInvestigator

Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies

Advanced Esophageal CancersCancers of Non-thoracic Origin With Metastases to the Lungs or PleuraNon-Small-Cell Lung Carcinoma+2 more
Completed
NCT00094978Phase 1PrincipalInvestigator

Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum

Carcinoma, Non-Small-Cell LungCarcinoma, Small CellEsophageal Neoplasms+1 more
Terminated
NCT01160445Phase 2PrincipalInvestigator

Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer

Metastatic MelanomaMetastatic Renal Cancer
Terminated
NCT01258868Phase 1PrincipalInvestigator

Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas

Esophageal CancerLung CancerMesolthelioma+2 more
Terminated
NCT01341496Phase 1PrincipalInvestigator

Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor Removal

Epithelial MalignanciesMelanomaPleural Malignancy+1 more
Terminated
NCT02839694Phase 1PrincipalInvestigator

Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy

MelanomaNeoplasm MetastasisNeoplasms, Germ Cell and Embryonal+1 more
Withdrawn
NCT05642195Phase 1/2PrincipalInvestigator

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell LungCarcinomasNon-Small Cell Lung Cancer+1 more
Suspended