Key Insights

Highlights

Success Rate

75% trial completion

Published Results

327 trials with published results (22%)

Research Maturity

685 completed trials (47% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.9%

232 terminated out of 1462 trials

Success Rate

74.7%

-11.8% vs benchmark

Late-Stage Pipeline

6%

87 trials in Phase 3/4

Results Transparency

48%

327 of 685 completed with results

Key Signals

327 with results75% success232 terminated

Data Visualizations

Phase Distribution

1,179Total
Not Applicable (169)
Early P 1 (22)
P 1 (552)
P 2 (349)
P 3 (77)
P 4 (10)

Trial Status

Completed685
Terminated232
Recruiting187
Unknown145
Active Not Recruiting120
Withdrawn48

Trial Success Rate

74.7%

Benchmark: 86.5%

Based on 685 completed trials

Clinical Trials (1462)

Showing 20 of 20 trials
NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT05355701Phase 1RecruitingPrimary

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

NCT07328516Enrolling By Invitation

Natural History Study of Early Life Exposures in Agriculture (ELEA)

NCT07574047Phase 2Not Yet RecruitingPrimary

MELCHRONO: A Prospective Randomized Study Investigating Chrono-immunotherapy for Advanced Melanoma.

NCT01366144Phase 1Active Not Recruiting

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

NCT07005297Not Yet RecruitingPrimary

Clinical Genetics Branch Eligibility Screening Survey

NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT05470283Phase 1Active Not Recruiting

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT04996823Phase 2Active Not RecruitingPrimary

Axitinib + Ipilimumab in Advanced Melanoma

NCT06305247Phase 1Active Not RecruitingPrimary

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

NCT02718066Phase 1CompletedPrimary

Study of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer

NCT04198766Phase 1Recruiting

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

NCT05538130Phase 1RecruitingPrimary

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

NCT06081920Phase 2RecruitingPrimary

A Study of IBI363 in Subjects With Advanced Melanoma

NCT06627595RecruitingPrimary

Impact of Physical Activity on Immunotherapy-induced Toxicities in Melanoma Management

NCT05373823Not ApplicableRecruitingPrimary

MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors

NCT00923026Enrolling By InvitationPrimary

Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies

NCT07686835Phase 2Recruiting

Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma.

NCT07518043Phase 1Recruiting

A Study of HLX18 vs. OPDIVO® in Multiple Resected Solid Tumors

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