Key Insights

Highlights

Success Rate

84% trial completion

Published Results

121 trials with published results (12%)

Research Maturity

437 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.3%

86 terminated out of 1030 trials

Success Rate

83.6%

-3.0% vs benchmark

Late-Stage Pipeline

8%

83 trials in Phase 3/4

Results Transparency

28%

121 of 437 completed with results

Key Signals

121 with results84% success86 terminated

Data Visualizations

Phase Distribution

791Total
Not Applicable (225)
Early P 1 (5)
P 1 (209)
P 2 (269)
P 3 (64)
P 4 (19)

Trial Status

Completed437
Recruiting191
Unknown182
Terminated86
Not Yet Recruiting50
Active Not Recruiting49

Trial Success Rate

83.6%

Benchmark: 86.5%

Based on 437 completed trials

Clinical Trials (1030)

Showing 20 of 20 trials
NCT06414902Phase 1RecruitingPrimary

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

NCT06862479Enrolling By Invitation

Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences(ES-LCCE-UDFM)

NCT06239194Phase 1Recruiting

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

NCT02012699Recruiting

Integrated Cancer Repository for Cancer Research

NCT04986293Not ApplicableRecruiting

CPAP or BiPAP for Motion Mitigation During Radiotherapy

NCT07307560Not ApplicableRecruiting

High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients

NCT02838836Recruiting

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

NCT06469944Phase 1Recruiting

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

NCT06445972Phase 1Recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

NCT07124000Recruiting

DESTINY-PANTUMOUR04

NCT07561840Not ApplicableNot Yet RecruitingPrimary

Exercise Training After Upper Gastrointestinal Cancer Surgery

NCT05357846Phase 3Recruiting

PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101)

NCT06710756Phase 1Recruiting

Lead-212 PSV359 Therapy for Patients With Solid Tumors

NCT00342654CompletedPrimary

Nutrition Intervention Trials in Linxian Follow-up Study

NCT05187182Phase 1Recruiting

CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer

NCT07549269CompletedPrimary

Comparison of Nab-Paclitaxel Versus Paclitaxel in Neoadjuvant Immunochemotherapy Therapy for Esophageal Squamous Cell Carcinoma: A Retrospective IPTW-Adjusted Analysis

NCT06712706Active Not RecruitingPrimary

Effect of Feeding Jejunostomy on Sarcopenia in Patients With Esophageal Cancer

NCT07519655Phase 1Recruiting

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

NCT00937456Not ApplicableCompletedPrimary

Open Versus Laparoscopically-assisted Esophagectomy for Cancer

NCT05480384Phase 2Active Not Recruiting

Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction

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