Key Insights

Highlights

Success Rate

68% trial completion

Published Results

42 trials with published results (20%)

Research Maturity

78 completed trials (37% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

17.6%

37 terminated out of 210 trials

Success Rate

67.8%

-18.7% vs benchmark

Late-Stage Pipeline

5%

11 trials in Phase 3/4

Results Transparency

54%

42 of 78 completed with results

Key Signals

42 with results68% success37 terminated

Data Visualizations

Phase Distribution

175Total
Not Applicable (16)
Early P 1 (5)
P 1 (84)
P 2 (59)
P 3 (7)
P 4 (4)

Trial Status

Completed78
Terminated37
Recruiting37
Unknown20
Active Not Recruiting19
Withdrawn9

Trial Success Rate

67.8%

Benchmark: 86.5%

Based on 78 completed trials

Clinical Trials (210)

Showing 20 of 20 trials
NCT06051695Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT03830229RecruitingPrimary

Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

NCT07277413Phase 1Recruiting

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

NCT05960773Phase 2SuspendedPrimary

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

NCT01950572Recruiting

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

NCT06885697Phase 1RecruitingPrimary

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

NCT04431024Recruiting

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

NCT03918252Phase 2Active Not RecruitingPrimary

Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma

NCT06710756Phase 1Recruiting

Lead-212 PSV359 Therapy for Patients With Solid Tumors

NCT05579366Phase 1Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

NCT04981119Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT03935893Phase 2Active Not Recruiting

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

NCT06477419Phase 2RecruitingPrimary

A Study of Sacituzumab Govitecan in People With Mesothelioma

NCT07602946Phase 2Not Yet RecruitingPrimary

SELECTmeso A Trial for Patients With Relapsed Malignant Mesothelioma SELECTmeso1 A Trial of BMS-986504 in Patients With MTAP-deficient Relapsed Mesothelioma

NCT06885424Enrolling By Invitation

A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products

NCT06503146Phase 2Recruiting

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

NCT00715611Phase 2Active Not RecruitingPrimary

Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma

NCT02012699Recruiting

Integrated Cancer Repository for Cancer Research

NCT03683680Not ApplicableRecruitingPrimary

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

NCT01851395Terminated

Rapid Autopsy and Procurement of Cancer Tissue

Scroll to load more

Research Network

Activity Timeline