Key Insights

Highlights

Success Rate

76% trial completion

Published Results

15 trials with published results (9%)

Research Maturity

70 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

12.9%

22 terminated out of 170 trials

Success Rate

76.1%

-10.5% vs benchmark

Late-Stage Pipeline

11%

19 trials in Phase 3/4

Results Transparency

21%

15 of 70 completed with results

Key Signals

15 with results76% success22 terminated

Data Visualizations

Phase Distribution

131Total
Not Applicable (44)
P 1 (24)
P 2 (44)
P 3 (13)
P 4 (6)

Trial Status

Completed70
Unknown39
Recruiting27
Terminated22
Withdrawn5
Active Not Recruiting3

Trial Success Rate

76.1%

Benchmark: 86.6%

Based on 70 completed trials

Clinical Trials (170)

Showing 20 of 20 trials
NCT06469944Phase 1Recruiting

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

NCT07114601Phase 1Recruiting

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT07213791Phase 1Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

NCT07745322Active Not Recruiting

Spatial MSC Index for Predicting Anti-PD-1 Efficacy in Esophageal Cancer

NCT06445972Phase 1Recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

NCT06077981Not ApplicableRecruitingPrimary

Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections

NCT06070376Not ApplicableRecruitingPrimary

Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of Esophagus.

NCT01719926Phase 1Completed

Phase I Platinum Based Chemotherapy Plus Indomethacin

NCT04513418Phase 3Active Not RecruitingPrimary

Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy

NCT05698992Recruiting

Rehabilitation and Recovery for Persons With Esophageal or Gastric Cancer

NCT06380816Phase 1Recruiting

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

NCT06862479Enrolling By Invitation

Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences(ES-LCCE-UDFM)

NCT07518680Not ApplicableNot Yet RecruitingPrimary

A Clinical Study on the Effect of Massaging Tian Tu Acupoint on Coughing After Esophageal Surgery

NCT02530983RecruitingPrimary

Mayo Clinic Upper Digestive Disease Survey

NCT07482566Not ApplicableRecruiting

Proximal Versus Total Gastrectomy for Locally Advanced Siewert Type II-III Gastroesophageal Junction Cancer

NCT02359968Phase 2CompletedPrimary

PReoperative Chemoradiation (Paclitaxel-carboplatin or FOLFOX) for Resectable Esophageal and Junctional Cancer

NCT05875870Not ApplicableRecruiting

Effects of Bright-light Exposure Combined With Specific Exercise Training (BEST) Program in Patients With Cancer

NCT06027515Not ApplicableCompleted

Esophageal Cancer Multimodal Prehabilitation Study

NCT04359732Not ApplicableActive Not Recruiting

Assessment of Response to nCRT for GEJ Cancer Using a Fully Integrated PET/MRI

NCT07272382Not ApplicableRecruitingPrimary

Omega-3 Fatty Acids With PD-1 Inhibitors in Advanced Esophageal Cancer

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