Key Insights

Highlights

Success Rate

60% trial completion

Published Results

17 trials with published results (26%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

26.2%

17 terminated out of 65 trials

Success Rate

60.5%

-26.0% vs benchmark

Late-Stage Pipeline

15%

10 trials in Phase 3/4

Results Transparency

65%

17 of 26 completed with results

Key Signals

17 with results60% success17 terminated

Data Visualizations

Phase Distribution

60Total
Not Applicable (4)
P 1 (24)
P 2 (22)
P 3 (10)

Trial Status

Completed26
Terminated17
Recruiting8
Unknown7
Withdrawn4
Active Not Recruiting2

Trial Success Rate

60.5%

Benchmark: 86.5%

Based on 26 completed trials

Clinical Trials (65)

Showing 20 of 20 trials
NCT06694454Phase 1Recruiting

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

NCT00720785Phase 1Completed

Natural Killer Cells and Bortezomib to Treat Cancer

NCT06868277Phase 3RecruitingPrimary

A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

NCT04389632Phase 1RecruitingPrimary

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

NCT07227298Phase 1Recruiting

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

NCT05358249Phase 1Active Not Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

NCT04499053Phase 2RecruitingPrimary

Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer

NCT05647122Phase 1Recruiting

First in Human Study of AZD9592 in Solid Tumors

NCT04748419Phase 1Active Not Recruiting

Safety & Efficacy of Consolidative Hypofractionated Radiation Therapy for Boosting Residual Lung Cancer With Durvalumab

NCT04486833Phase 1RecruitingPrimary

Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

NCT06908304Phase 3RecruitingPrimary

A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC

NCT06549816Phase 1CompletedPrimary

A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors

NCT04993677Phase 2Completed

A Study of SEA-CD40 Given With Other Drugs in Cancers

NCT02487095Phase 1CompletedPrimary

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

NCT04665921Phase 1TerminatedPrimary

A Study of SGN-STNV in Advanced Solid Tumors

NCT04167657Phase 2CompletedPrimary

SinTilimab After Radiation (STAR Study)

NCT02098954Phase 2UnknownPrimary

Erlotinib Combined With Chemotherapy in TKI Resistant Non-Small Cell Lung Cancers

NCT01514864Phase 2TerminatedPrimary

Trial of Dasatinib in Patients With Advanced Cancers Harboring DDR2 Mutation or Inactivating B-RAF Mutation

NCT06127329Not ApplicableNot Yet RecruitingPrimary

Efficacy and Safety of BAI Combined With DEB-BACE of EqualSpheres in the Treatment of Advanced NSCLC

NCT02961283Phase 1Terminated

Study of ASN003 in Subjects With Advanced Solid Tumors

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