Success Metrics

Clinical Success Rate
60.5%

Based on 144 completed trials

Completion Rate
61%(144/238)
Active Trials
139(31%)
Results Posted
96%(138 trials)
Terminated
94(21%)

Phase Distribution

Ph phase_3
45
10%
Ph not_applicable
12
3%
Ph phase_1
202
46%
Ph early_phase_1
2
0%
Ph phase_4
5
1%
Ph phase_2
170
38%

Phase Distribution

204

Early Stage

170

Mid Stage

50

Late Stage

Phase Distribution436 total trials
Early Phase 1First-in-human
2(0.5%)
Phase 1Safety & dosage
202(46.3%)
Phase 2Efficacy & side effects
170(39.0%)
Phase 3Large-scale testing
45(10.3%)
Phase 4Post-market surveillance
5(1.1%)
N/ANon-phased studies
12(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

56.5%

144 of 255 finished

Non-Completion Rate

43.5%

111 ended early

Currently Active

139

trials recruiting

Total Trials

442

all time

Status Distribution
Active(155)
Completed(144)
Terminated(111)
Other(32)

Detailed Status

Completed144
Recruiting95
Terminated94
Active, not recruiting44
unknown26
Withdrawn17

Development Timeline

Analytics

Development Status

Total Trials
442
Active
139
Success Rate
60.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.5%)
Phase 1202 (46.3%)
Phase 2170 (39.0%)
Phase 345 (10.3%)
Phase 45 (1.1%)
N/A12 (2.8%)

Trials by Status

enrolling_by_invitation10%
withdrawn174%
not_yet_recruiting153%
active_not_recruiting4410%
completed14433%
recruiting9521%
suspended61%
terminated9421%
unknown266%

Recent Activity

Clinical Trials (442)

Showing 20 of 442 trialsScroll for more
NCT04401748Phase 3

Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

Active Not Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05829226Phase 1

A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

Completed
NCT05554406Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT06177067Phase 1

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
NCT04493138Phase 1

Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations

Active Not Recruiting
NCT04588922Phase 1

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Recruiting
NCT05182957Phase 2

Clinical Study on Anti-PD-1 Plus Lenalidomide and Azacitidine in Relapsed/Refractory Peripheral T-cell Lymphoma

Recruiting
NCT04256317Phase 2

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

Recruiting
NCT06497062Phase 2

Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT01522976Phase 2

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Active Not Recruiting
NCT00658814Phase 2

Azacitidine and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

Active Not Recruiting
NCT04501120Phase 1

Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML

Recruiting
NCT05183035Phase 3

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Recruiting
NCT05586074Phase 3

HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML

Recruiting
NCT04771130Phase 1

A Study of BGB-11417 in Participants With Myeloid Malignancies

Recruiting
NCT05428969Phase 1

A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies

Active Not Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
442