Success Metrics

Clinical Success Rate
61.1%

Based on 149 completed trials

Completion Rate
61%(149/244)
Active Trials
144(32%)
Results Posted
95%(141 trials)
Terminated
95(21%)

Phase Distribution

Ph phase_3
46
10%
Ph phase_1
207
46%
Ph phase_4
5
1%
Ph early_phase_1
2
0%
Ph not_applicable
13
3%
Ph phase_2
175
39%

Phase Distribution

209

Early Stage

175

Mid Stage

51

Late Stage

Phase Distribution448 total trials
Early Phase 1First-in-human
2(0.4%)
Phase 1Safety & dosage
207(46.2%)
Phase 2Efficacy & side effects
175(39.1%)
Phase 3Large-scale testing
46(10.3%)
Phase 4Post-market surveillance
5(1.1%)
N/ANon-phased studies
13(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

57.1%

149 of 261 finished

Non-Completion Rate

42.9%

112 ended early

Currently Active

144

trials recruiting

Total Trials

454

all time

Status Distribution
Active(163)
Completed(149)
Terminated(112)
Other(30)

Detailed Status

Completed149
Recruiting97
Terminated95
Active, not recruiting47
unknown24
Not yet recruiting18

Development Timeline

Analytics

Development Status

Total Trials
454
Active
144
Success Rate
61.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.4%)
Phase 1207 (46.2%)
Phase 2175 (39.1%)
Phase 346 (10.3%)
Phase 45 (1.1%)
N/A13 (2.9%)

Trials by Status

active_not_recruiting4710%
unknown245%
not_yet_recruiting184%
recruiting9721%
completed14933%
enrolling_by_invitation10%
terminated9521%
withdrawn174%
suspended61%

Recent Activity

Clinical Trials (454)

Showing 20 of 454 trialsScroll for more
NCT07490288Not Applicable

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

Recruiting
NCT00392353Phase 1

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Active Not Recruiting
NCT03573024Phase 2

Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid Leukemia

Completed
NCT06265545Not Applicable

Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia

Recruiting
NCT06456463Phase 2

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Active Not Recruiting
NCT06465953Phase 3

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

Recruiting
NCT05554406Phase 2

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07581002Phase 2

A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

Recruiting
NCT04284787Phase 2

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT06177067Phase 1

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
NCT07478991Phase 3

Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)

Recruiting
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT07743112Phase 2

A Phase 2 Study of MAX-40279 Combined With Venetoclax and Azacitidine in Unfit Newly Diagnosed Acute Myeloid Leukemia

Recruiting
NCT06514261Phase 1

Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML

Suspended
NCT01522976Phase 2

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Active Not Recruiting
NCT06232655Phase 2

Cladribine Venetoclax in Monocytic AML

Active Not Recruiting
NCT07679334Phase 1

Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms

Not Yet Recruiting
NCT03628209Phase 1

Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
454