Success Metrics

Clinical Success Rate
61.1%

Based on 149 completed trials

Completion Rate
61%(149/244)
Active Trials
142(31%)
Results Posted
95%(141 trials)
Terminated
95(21%)

Phase Distribution

Ph phase_1
207
46%
Ph early_phase_1
2
0%
Ph not_applicable
12
3%
Ph phase_2
174
38%
Ph phase_3
46
10%
Ph phase_4
5
1%

Phase Distribution

209

Early Stage

174

Mid Stage

51

Late Stage

Phase Distribution446 total trials
Early Phase 1First-in-human
2(0.4%)
Phase 1Safety & dosage
207(46.4%)
Phase 2Efficacy & side effects
174(39.0%)
Phase 3Large-scale testing
46(10.3%)
Phase 4Post-market surveillance
5(1.1%)
N/ANon-phased studies
12(2.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

57.1%

149 of 261 finished

Non-Completion Rate

42.9%

112 ended early

Currently Active

142

trials recruiting

Total Trials

452

all time

Status Distribution
Active(161)
Completed(149)
Terminated(112)
Other(30)

Detailed Status

Completed149
Recruiting96
Terminated95
Active, not recruiting46
unknown24
Not yet recruiting18

Development Timeline

Analytics

Development Status

Total Trials
452
Active
142
Success Rate
61.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.4%)
Phase 1207 (46.4%)
Phase 2174 (39.0%)
Phase 346 (10.3%)
Phase 45 (1.1%)
N/A12 (2.7%)

Trials by Status

enrolling_by_invitation10%
not_yet_recruiting184%
active_not_recruiting4610%
recruiting9621%
suspended61%
completed14933%
unknown245%
withdrawn174%
terminated9521%

Recent Activity

Clinical Trials (452)

Showing 20 of 452 trialsScroll for more
NCT06514261Phase 1

Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML

Suspended
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT05554406Phase 2

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Recruiting
NCT06232655Phase 2

Cladribine Venetoclax in Monocytic AML

Active Not Recruiting
NCT01522976Phase 2

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Active Not Recruiting
NCT07581002Phase 2

A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07679334Phase 1

Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms

Not Yet Recruiting
NCT03628209Phase 1

Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma

Active Not Recruiting
NCT07478991Phase 3

Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)

Recruiting
NCT07735117Phase 3

Mitoxantrone Hydrochloride Liposome, Cytarabine, G-CSF Plus Venetoclax vs. Azacitidine Plus Venetoclax for MDS-IB2 and Secondary/Elderly AML

Not Yet Recruiting
NCT06616636Phase 1

A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)

Recruiting
NCT04588922Phase 1

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Recruiting
NCT05955261Phase 2

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

Suspended
NCT06763341Phase 1

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
NCT05201066Phase 2

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.

Active Not Recruiting
NCT07722767Phase 1

A Phase 1b Study of CLN-049 in Combination With Azacitidine and Venetoclax in AML Patients

Not Yet Recruiting
NCT04603001Phase 1

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Active Not Recruiting
NCT04227847Phase 1

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

Recruiting
NCT07645469Phase 1

FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
452