Success Metrics

Clinical Success Rate
73.9%

Based on 116 completed trials

Completion Rate
74%(116/157)
Active Trials
64(22%)
Results Posted
72%(83 trials)
Terminated
41(14%)

Phase Distribution

Ph phase_4
6
2%
Ph early_phase_1
4
1%
Ph not_applicable
5
2%
Ph phase_3
23
8%
Ph phase_2
113
39%
Ph phase_1
135
47%

Phase Distribution

139

Early Stage

113

Mid Stage

29

Late Stage

Phase Distribution286 total trials
Early Phase 1First-in-human
4(1.4%)
Phase 1Safety & dosage
135(47.2%)
Phase 2Efficacy & side effects
113(39.5%)
Phase 3Large-scale testing
23(8.0%)
Phase 4Post-market surveillance
6(2.1%)
N/ANon-phased studies
5(1.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.2%

116 of 170 finished

Non-Completion Rate

31.8%

54 ended early

Currently Active

64

trials recruiting

Total Trials

290

all time

Status Distribution
Active(74)
Completed(116)
Terminated(54)
Other(46)

Detailed Status

Completed116
unknown43
Terminated41
Recruiting40
Active, not recruiting24
Withdrawn13

Development Timeline

Analytics

Development Status

Total Trials
290
Active
64
Success Rate
73.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (1.4%)
Phase 1135 (47.2%)
Phase 2113 (39.5%)
Phase 323 (8.0%)
Phase 46 (2.1%)
N/A5 (1.7%)

Trials by Status

completed11640%
suspended31%
unknown4315%
terminated4114%
active_not_recruiting248%
not_yet_recruiting103%
recruiting4014%
withdrawn134%

Recent Activity

Clinical Trials (290)

Showing 20 of 290 trialsScroll for more
NCT06930651Phase 1

A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid Malignancies

Recruiting
NCT05829226Phase 1

A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

Completed
NCT07374029Phase 1

Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML

Recruiting
NCT07012044Phase 1

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

Not Yet Recruiting
NCT00095784Phase 2

Decitabine in Treating Patients With Myelofibrosis

Active Not Recruiting
NCT07555405Phase 4

Evaluating the Safety and Efficacy of Decitabine in the Treatment of XMEN Patients

Not Yet Recruiting
NCT02890329Phase 1

Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Active Not Recruiting
NCT05586074Phase 3

HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML

Recruiting
NCT06129734Phase 1

Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant

Recruiting
NCT01627041Phase 2

Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT06401603Phase 1

A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia

Recruiting
NCT03164057Phase 2

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Active Not Recruiting
NCT06923488Phase 1

Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory Myelodysplastic Syndromes

Recruiting
NCT03184935Phase 1

Research for Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-MDS) in the Treatment of Myelodysplastic Syndrome (MDS)

Suspended
NCT03009240Phase 1

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

Completed
NCT02957968Phase 2

Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca

Active Not Recruiting
NCT05222984Phase 1

Navitoclax, Venetoclax, and Decitabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Previously Treated With Venetoclax

Active Not Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT03132454Phase 1

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

Active Not Recruiting
NCT05038592Phase 1

Phase I/II Study of Tagraxofusp in Combination With Decitabine for Patients With Myelomonocytic/Myeloproliferative Neoplasm and High Risk Myelodysplastic Syndromes

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
290