External Oblique and Rectus Abdominis Plane (EXORA) Block for Postoperative Analgesia in Patients Undergoing Umbilical Hernia Repair

NCT07012603 | Completed

• 1 other identifier: 36264PR1207/5/25
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effect of the external oblique and rectus abdominis plane (EXORA) block for postoperative analgesia in patients undergoing umbilical hernia repair.

Conditions

External Oblique and Rectus Abdominis Plane; Postoperative Analgesia; Umbilical Hernia Repair

Outcome Measures

Primary Outcomes (1)

• Total morphine consumption

  Rescue analgesia of morphine will be given as 5 mg bolus if the numeric rating scale (NRS) \> 3 to be repeated after 30 min if pain persists until the NRS \< 4.

  24 hours postoperatively

Secondary Outcomes (6)

• Time to the 1st rescue analgesia

  24 hours postoperatively

• Intraoperative fentanyl consumption

  Intraoperatively

• Degree of pain

  24 hours postoperatively

• Mean arterial pressure

  Till the end of surgery (Up to 2 hours)

• Heart rate

  Till the end of surgery (Up to 2 hours)

Study Arms (2)

EXORA block group

EXPERIMENTAL

Patients will receive an external oblique and rectus abdominis plane (EXORA) block using 20 mL of bupivacaine 0.25%.

Other: External oblique and rectus abdominis plane (EXORA) block

Control group

SHAM COMPARATOR

Patients will receive a sham block using 20 mL of normal saline as a control group.

Other: Sham block

Interventions

External oblique and rectus abdominis plane (EXORA) block OTHER

Patients will receive an external oblique and rectus abdominis plane (EXORA) block using 20 mL of bupivacaine 0.25%.

EXORA block group

Sham block OTHER

Patients will receive a sham block using 20 mL of normal saline as a control group.

Control group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age from 18 to 65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Undergoing umbilical hernia repair.

You may not qualify if:

• History of allergies to local anesthetics.
• Bleeding or coagulation disorders.
• Anatomical abnormalities.
• Psychiatric and neurological disorders.
• Local infection at the site of injection.
• Complicated hernial defects \[strangulated, incarcerated, or obstructed cases\].

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location

MeSH Terms

Interventions

Dental Occlusion

Intervention Hierarchy (Ancestors)

Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: May 31, 2025
• First Posted: June 10, 2025
• Study Start: June 10, 2025
• Primary Completion: March 19, 2026
• Study Completion: March 19, 2026
• Last Updated: April 22, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)