NCT00005685

Brief Summary

To examine racial and psychosocial influences on blood pressure control.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 1983

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 1983

Completed
16.7 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
2.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2002

Completed
Last Updated

May 13, 2016

Status Verified

January 1, 2006

First QC Date

May 25, 2000

Last Update Submit

May 12, 2016

Conditions

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (26)

  • Girdler SS, Turner JR, Sherwood A, Light KC. Gender differences in blood pressure control during a variety of behavioral stressors. Psychosom Med. 1990 Sep-Oct;52(5):571-91. doi: 10.1097/00006842-199009000-00009.

    PMID: 2247562BACKGROUND
  • Turner JR, Sherwood A. Postural effects on blood pressure reactivity: implications for studies of laboratory-field generalization. J Psychosom Res. 1991;35(2-3):289-95. doi: 10.1016/0022-3999(91)90083-z.

    PMID: 2046061BACKGROUND
  • Hinderliter AL, Light KC, Willis PW 4th. Left ventricular mass index and diastolic filling. Relation to blood pressure and demographic variables in a healthy biracial sample. Am J Hypertens. 1991 Jul;4(7 Pt 1):579-85. doi: 10.1093/ajh/4.7.579.

    PMID: 1873012BACKGROUND
  • Turner JR, Sherwood A, Light KC. Generalization of cardiovascular response: supportive evidence for the reactivity hypothesis. Int J Psychophysiol. 1991 Aug;11(2):207-12. doi: 10.1016/0167-8760(91)90013-n.

    PMID: 1748596BACKGROUND
  • Hinderliter AL, Light KC, Willis PW 4th. Gender differences in left ventricular structure and function in young adults with normal or marginally elevated blood pressure. Am J Hypertens. 1992 Jan;5(1):32-6. doi: 10.1093/ajh/5.1.32.

    PMID: 1736932BACKGROUND
  • Light KC, Turner JR. Stress-induced changes in the rate of sodium excretion in healthy black and white men. J Psychosom Res. 1992 Jul;36(5):497-508. doi: 10.1016/0022-3999(92)90011-p.

    PMID: 1619590BACKGROUND
  • Light KC, Turner JR, Hinderliter AL. Job strain and ambulatory work blood pressure in healthy young men and women. Hypertension. 1992 Aug;20(2):214-8. doi: 10.1161/01.hyp.20.2.214.

    PMID: 1639463BACKGROUND
  • Sherwood A, Royal SA, Hutcheson JS, Turner JR. Comparison of impedance cardiographic measurements using band and spot electrodes. Psychophysiology. 1992 Nov;29(6):734-41. doi: 10.1111/j.1469-8986.1992.tb02051.x.

    PMID: 1461960BACKGROUND
  • Light KC, Dolan CA, Davis MR, Sherwood A. Cardiovascular responses to an active coping challenge as predictors of blood pressure patterns 10 to 15 years later. Psychosom Med. 1992 Mar-Apr;54(2):217-30. doi: 10.1097/00006842-199203000-00007.

    PMID: 1565757BACKGROUND
  • Girdler SS, Hinderliter AL, Light KC. Peripheral adrenergic receptor contributions to cardiovascular reactivity: influence of race and gender. J Psychosom Res. 1993;37(2):177-93. doi: 10.1016/0022-3999(93)90085-t.

    PMID: 8385216BACKGROUND
  • Sherwood A, Hinderliter AL. Responsiveness to alpha- and beta-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men. Am J Hypertens. 1993 Jul;6(7 Pt 1):630-5. doi: 10.1093/ajh/6.7.630.

    PMID: 8398005BACKGROUND
  • Light KC, Turner JR, Hinderliter AL, Sherwood A. Race and gender comparisons: I. Hemodynamic responses to a series of stressors. Health Psychol. 1993 Sep;12(5):354-65. doi: 10.1037//0278-6133.12.5.354.

    PMID: 8223359BACKGROUND
  • Light KC, Turner JR, Hinderliter AL, Sherwood A. Race and gender comparisons: II. Predictions of work blood pressure from laboratory baseline and cardiovascular reactivity measures. Health Psychol. 1993 Sep;12(5):366-75. doi: 10.1037//0278-6133.12.5.366.

    PMID: 8223360BACKGROUND
  • Turner JR, Sherwood A, Light KC. Intertask consistency of hemodynamic responses to laboratory stressors in a biracial sample of men and women. Int J Psychophysiol. 1994 Jul;17(2):159-64. doi: 10.1016/0167-8760(94)90031-0.

    PMID: 7995778BACKGROUND
  • Hinderliter AL, Light KC, Willis PW 4th. Patients with borderline elevated blood pressure have enhanced left ventricular contractility. Am J Hypertens. 1995 Oct;8(10 Pt 1):1040-5. doi: 10.1016/0895-7061(95)00256-1.

    PMID: 8845073BACKGROUND
  • Hinderliter AL, Sager AR, Sherwood A, Light KC, Girdler SS, Willis PW 4th. Ethnic differences in forearm vasodilator capacity. Am J Cardiol. 1996 Jul 15;78(2):208-11. doi: 10.1016/s0002-9149(96)90397-5.

    PMID: 8712144BACKGROUND
  • Light KC, Brownley KA, Turner JR, Hinderliter AL, Girdler SS, Sherwood A, Anderson NB. Job status and high-effort coping influence work blood pressure in women and blacks. Hypertension. 1995 Apr;25(4 Pt 1):554-9. doi: 10.1161/01.hyp.25.4.554.

    PMID: 7721397BACKGROUND
  • Sherwood A, Hinderliter AL, Light KC. Physiological determinants of hyperreactivity to stress in borderline hypertension. Hypertension. 1995 Mar;25(3):384-90. doi: 10.1161/01.hyp.25.3.384.

    PMID: 7875764BACKGROUND
  • Brownley KA, Light KC, Anderson NB. Social support and hostility interact to influence clinic, work, and home blood pressure in black and white men and women. Psychophysiology. 1996 Jul;33(4):434-45. doi: 10.1111/j.1469-8986.1996.tb01069.x.

    PMID: 8753944BACKGROUND
  • Brownley KA, West SG, Hinderliter AL, Light KC. Acute aerobic exercise reduces ambulatory blood pressure in borderline hypertensive men and women. Am J Hypertens. 1996 Mar;9(3):200-6. doi: 10.1016/0895-7061(95)00335-5.

    PMID: 8695017BACKGROUND
  • Girdler SS, Pedersen CA, Light KC. Thyroid axis function during the menstrual cycle in women with premenstrual syndrome. Psychoneuroendocrinology. 1995;20(4):395-403. doi: 10.1016/0306-4530(94)00068-9.

    PMID: 8532823BACKGROUND
  • Light KC, Girdler SS, Sherwood A, Bragdon EE, Brownley KA, West SG, Hinderliter AL. High stress responsivity predicts later blood pressure only in combination with positive family history and high life stress. Hypertension. 1999 Jun;33(6):1458-64. doi: 10.1161/01.hyp.33.6.1458.

    PMID: 10373233BACKGROUND
  • West SG, Light KC, Hinderliter AL, Stanwyck CL, Bragdon EE, Brownley KA. Potassium supplementation induces beneficial cardiovascular changes during rest and stress in salt sensitive individuals. Health Psychol. 1999 May;18(3):229-40. doi: 10.1037//0278-6133.18.3.229.

    PMID: 10357504BACKGROUND
  • West SG, Brownley KA, Light KC. Postexercise vasodilatation reduces diastolic blood pressure responses to stress. Ann Behav Med. 1998 Spring;20(2):77-83. doi: 10.1007/BF02884452.

    PMID: 9989312BACKGROUND
  • Brownley KA, Hinderliter AL, West SG, Girdler SS, Sherwood A, Light KC. Sympathoadrenergic mechanisms in reduced hemodynamic stress responses after exercise. Med Sci Sports Exerc. 2003 Jun;35(6):978-86. doi: 10.1249/01.MSS.0000069335.12756.1B.

    PMID: 12783046BACKGROUND
  • Grewen KM, Girdler SS, Hinderliter A, Light KC. Depressive symptoms are related to higher ambulatory blood pressure in people with a family history of hypertension. Psychosom Med. 2004 Jan-Feb;66(1):9-16. doi: 10.1097/01.psy.0000106881.60228.16.

    PMID: 14747632BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesHypertension

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Officials

  • Kathleen Light

    University of North Carolina

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

September 1, 1983

Study Completion

July 1, 2002

Last Updated

May 13, 2016

Record last verified: 2006-01