NCT00005170

Brief Summary

To determine ways in which behavioral factors influenced the diagnosis and development of hypertension in adult working populations.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Dec 1984

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 1984

Completed
8.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 1993

Completed
7.3 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
Last Updated

May 13, 2016

Status Verified

April 1, 2000

First QC Date

May 25, 2000

Last Update Submit

May 12, 2016

Conditions

Cardiovascular DiseasesHeart DiseasesHypertension

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (57)

  • Roman MJ, Pickering TG, Schwartz JE, Cavallini MC, Pini R, Devereux RB. Is the absence of a normal nocturnal fall in blood pressure (nondipping) associated with cardiovascular target organ damage? J Hypertens. 1997 Sep;15(9):969-78. doi: 10.1097/00004872-199715090-00007.

    PMID: 9321744BACKGROUND

  • Kleinert HD, Harshfield GA, Pickering TG, Devereux RB, Sullivan PA, Marion RM, Mallory WK, Laragh JH. What is the value of home blood pressure measurement in patients with mild hypertension? Hypertension. 1984 Jul-Aug;6(4):574-8. doi: 10.1161/01.hyp.6.4.574.

    PMID: 6235190BACKGROUND

  • Wallace JM, Thornton WE, Kennedy HL, Pickering TG, Harshfield GA, Frohlich ED, Gifford RW, Bolen K: Ambulatory Blood Pressure in 199 Normal Subjects. A Collaborative Study. In: Ambulatory Blood Pressure Monitoring, Weber MA, Drayer JIM (Eds). Steinkopff-Verlag. Darmstadt, pp. 117-127, 1984

    BACKGROUND

  • Pickering TG, Harshfield GA, Devereux RB: Ambulatory Monitoring of Blood Pressure: The Importance of Blood Pressure During Work. In: Ambulatory Blood Pressure Monitoring. Weber MA, Drayer JIM (Eds), Steinkopff-Verlag. Darmstadt, pp. 193-197, 1984

    BACKGROUND

  • Harshfield GA, Pickering TG, Blank S, Lindahl C, Stroud L, Laragh JH: Ambulatory Blood Pressure Monitoring: Records, Applications, and Analysis. In: Ambulatory Blood Pressure Monitoring. Weber MA, Drayer JIM (Eds). Steinkopff-Verlag. Darmstadt, pp. 1-7, 1984

    BACKGROUND

  • Schneiderman N, Pickering T: Hemodyamic and Electrophysiological Measures of Reactivity. In: Stress, Reactivity, and Cardiovascular Disease. Proceedings of the Working Conference. U.S. Department of Health and Human Services. NIH Publication No. 84-2698, p. 85-106, 1984

    BACKGROUND

  • Pickering TG, Harshfield GA, Devereux RB, Laragh JH. What is the role of ambulatory blood pressure monitoring in the management of hypertensive patients? Hypertension. 1985 Mar-Apr;7(2):171-7. doi: 10.1161/01.hyp.7.2.171.

    PMID: 3156813BACKGROUND

  • Thailer SA, Friedman R, Harshfield GA, Pickering TG. Psychologic differences between high-, normal-, and low-renin hypertensives. Psychosom Med. 1985 May-Jun;47(3):294-7. doi: 10.1097/00006842-198505000-00007.

    PMID: 3889967BACKGROUND

  • Pickering TG, Harshfield GA, Laragh JH. Ambulatory versus casual blood pressure in the diagnosis of hypertensive patients. Clin Exp Hypertens A. 1985;7(2-3):257-66. doi: 10.3109/10641968509073545. No abstract available.

    PMID: 3891153BACKGROUND

  • Harshfield GA, Pickering TG, Blank S, Laragh JH: How Well do Casual Blood Pressures Reflect Ambulatory Blood Pressure? In: Blood Pressure Recording in the Clinical Management of Hypertension. Giuseppe G (Ed). Edizioni L, Pozzi, pp. 50-54, 1985

    BACKGROUND

  • Lutas EM, Devereux RB, Reis G, Alderman MH, Pickering TG, Borer JS, Laragh JH. Increased cardiac performance in mild essential hypertension. Left ventricular mechanics. Hypertension. 1985 Nov-Dec;7(6 Pt 1):979-88. doi: 10.1161/01.hyp.7.6.979.

    PMID: 2934328BACKGROUND

  • Schneiderman N, Pickering TG: Cardiovascular Measures of Physiologic Reactivity. In: Handbook of Stress, Reactivity, & Cardiovascular Disease. Matthews KA, Weiss SM, Detre T, Dembroski TM, Falkner B, Manuck SB, Williams RB, Jr. (Eds). John Wiley & Sons, Inc, New York, pp. 145-186, 1986

    BACKGROUND

  • Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG, Laragh JH. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986 Aug;105(2):173-8. doi: 10.7326/0003-4819-105-2-173.

    PMID: 2942070BACKGROUND

  • Pickering TG, Harshfield GA, Blank S, James GD, Laragh JH, Clark L, Denby L, Pregibon D. Behavioral determinants of 24-hour blood pressure patterns in borderline hypertension. J Cardiovasc Pharmacol. 1986;8 Suppl 5:S89-92. doi: 10.1097/00005344-198608005-00017.

    PMID: 2427893BACKGROUND

  • James GD, Yee LS, Harshfield GA, Blank SG, Pickering TG. The influence of happiness, anger, and anxiety on the blood pressure of borderline hypertensives. Psychosom Med. 1986 Sep-Oct;48(7):502-8. doi: 10.1097/00006842-198609000-00005.

    PMID: 3763789BACKGROUND

  • Pickering TG, Cvetkovski B, James GD: An Evaluation of Electronic Recorders for Self-Monitoring of Blood Pressure. J Hypertens Supplement, 4(Supp. 5):S328-S330, 1986

    BACKGROUND

  • Clark LA, Denby L, Pregibon D, Harshfield GA, Pickering TG, Blank S, Laragh JH. A data-based method for bivariate outlier detection: application to automatic blood pressure recording devices. Psychophysiology. 1987 Jan;24(1):119-25. doi: 10.1111/j.1469-8986.1987.tb01872.x. No abstract available.

    PMID: 3575589BACKGROUND

  • Shear MK, Kligfield P, Harshfield G, Devereux RB, Polan JJ, Mann JJ, Pickering T, Frances AJ. Cardiac rate and rhythm in panic patients. Am J Psychiatry. 1987 May;144(5):633-7. doi: 10.1176/ajp.144.5.633.

    PMID: 2437810BACKGROUND

  • Pickering TG. Strategies for the evaluation and treatment of hypertension and some implications of blood pressure variability. Circulation. 1987 Jul;76(1 Pt 2):I77-82.

    PMID: 3297412BACKGROUND

  • Clark LA, Denby L, Pregibon D, Harshfield GA, Pickering TG, Blank S, Laragh JH. A quantitative analysis of the effects of activity and time of day on the diurnal variations of blood pressure. J Chronic Dis. 1987;40(7):671-81. doi: 10.1016/0021-9681(87)90103-2.

    PMID: 3597670BACKGROUND

  • Pickering TG, Devereux RB. Ambulatory monitoring of blood pressure as a predictor of cardiovascular risk. Am Heart J. 1987 Oct;114(4 Pt 2):925-8. doi: 10.1016/0002-8703(87)90589-8. No abstract available.

    PMID: 3661385BACKGROUND

  • Harshfield GA, Pickering TG, James GD, Blank SG: Variabilitat and Reaktivitat des Blutdruckes im Alltag. In: Indirekte 24-Stunden-Blutdruckmessung, pp. 103-115. Meyer-Sabellek, W, and Gotzen R (Eds). Steinkopff-Verlag. Darmstadt, 1988

    BACKGROUND

  • Pickering TG, Devereux RB: Prognose Kardiovaskularer Morbiditat mit hilfe der ambulanten Blutdruckaufzeichnung. In: Indirekete 24-Stunden-Blutdruckmessung, pp. 1233-240. (Ed) Meyer-Sabellek W, Gotzen R (Eds). Steinkopff-Verlag. Darmstadt, 1988

    BACKGROUND

  • James GD, Pickering TG, Yee LS, Harshfield GA, Riva S, Laragh JH. The reproducibility of average ambulatory, home, and clinic pressures. Hypertension. 1988 Jun;11(6 Pt 1):545-9. doi: 10.1161/01.hyp.11.6.545.

    PMID: 3384470BACKGROUND

  • Pickering TG, Gerin W. Ambulatory blood pressure monitoring and cardiovascular reactivity testing for the evaluation of the role of psychosocial factors and prognosis in hypertensive patients. Am Heart J. 1988 Aug;116(2 Pt 2):665-72. doi: 10.1016/0002-8703(88)90567-4.

    PMID: 3293411BACKGROUND

  • Pickering TG: The Study of Blood Pressure in Everyday Life. Behavioral Medicine in Cardiovascular Disorders, 5, 71-85, 1988

    BACKGROUND

  • Pickering TG: Blood Pressure Monitoring Outside the Clinic for Investigating the Role of Behavioral Factors in Hypertension. In: Handbook of Hypertension. Vol 9: Behavioral Factors in Hypertension. Julius S, and Bassett DR (Eds). Elsevier Science Publishers, New York, pp. 162-175, 1987

    BACKGROUND

  • Pickering TG, James GD, Boddie C, Harshfield GA, Blank S, Laragh JH. How common is white coat hypertension? JAMA. 1988 Jan 8;259(2):225-8.

    PMID: 3336140BACKGROUND

  • Pickering TG. Blood pressure monitoring outside the office for the evaluation of patients with resistant hypertension. Hypertension. 1988 Mar;11(3 Pt 2):II96-100. doi: 10.1161/01.hyp.11.3_pt_2.ii96.

    PMID: 3280500BACKGROUND

  • Harshfield GA, James GD, Schlussel Y, Yee LS, Blank SG, Pickering TG. Do laboratory tests of blood pressure reactivity predict blood pressure changes during everyday life? Am J Hypertens. 1988 Apr;1(2):168-74. doi: 10.1093/ajh/1.2.168.

    PMID: 3401355BACKGROUND

  • James GD, Yee LS, Harshfield GA, Pickering TG. Sex differences in factors affecting the daily variation of blood pressure. Soc Sci Med. 1988;26(10):1019-23. doi: 10.1016/0277-9536(88)90219-5.

    PMID: 3393919BACKGROUND

  • Pickering TG. The influence of daily activity on ambulatory blood pressure. Am Heart J. 1988 Oct;116(4):1141-5. doi: 10.1016/0002-8703(88)90178-0.

    PMID: 3177189BACKGROUND

  • Pickering TG, James GD. Some implications of the differences between home, clinic and ambulatory blood pressure in normotensive and hypertensive patients. J Hypertens Suppl. 1989 May;7(3):S65-72.

    PMID: 2668466BACKGROUND

  • Gerber LM, Schnall PL, Pickering TG. Body fat and its distribution in relation to casual and ambulatory blood pressure. Hypertension. 1990 May;15(5):508-13. doi: 10.1161/01.hyp.15.5.508.

    PMID: 2332242BACKGROUND

  • Schlussel YR, Schnall PL, Zimbler M, Warren K, Pickering TG. The effect of work environments on blood pressure: evidence from seven New York organizations. J Hypertens. 1990 Jul;8(7):679-85. doi: 10.1097/00004872-199007000-00012.

    PMID: 2168459BACKGROUND

  • Schnall PL, Pieper C, Schwartz JE, Karasek RA, Schlussel Y, Devereux RB, Ganau A, Alderman M, Warren K, Pickering TG. The relationship between 'job strain,' workplace diastolic blood pressure, and left ventricular mass index. Results of a case-control study. JAMA. 1990 Apr 11;263(14):1929-35.

    PMID: 2138234BACKGROUND

  • Pickering TG: Ambulatory Monitoring: Applications and Limitations. In: Handbook on Methods and Measurement in Cardiovascular Behavioral Medicine. Schniderman N et al (Eds) (In press), 0000

    BACKGROUND

  • Cavallini MC, Roman MJ, Pickering TG, Schwartz JE, Pini R, Devereux RB. Is white coat hypertension associated with arterial disease or left ventricular hypertrophy? Hypertension. 1995 Sep;26(3):413-9. doi: 10.1161/01.hyp.26.3.413.

    PMID: 7649575BACKGROUND

  • Landsbergis PA, Schnall PL, Warren K, Pickering TG, Schwartz JE. Association between ambulatory blood pressure and alternative formulations of job strain. Scand J Work Environ Health. 1994 Oct;20(5):349-63. doi: 10.5271/sjweh.1386.

    PMID: 7863299BACKGROUND

  • Roman MJ, Pickering TG, Schwartz JE, Pini R, Devereux RB. Association of carotid atherosclerosis and left ventricular hypertrophy. J Am Coll Cardiol. 1995 Jan;25(1):83-90. doi: 10.1016/0735-1097(94)00316-i.

    PMID: 7798531BACKGROUND

  • Schnall PL, Landsbergis PA, Baker D. Job strain and cardiovascular disease. Annu Rev Public Health. 1994;15:381-411. doi: 10.1146/annurev.pu.15.050194.002121. No abstract available.

    PMID: 8054091BACKGROUND

  • Gerin W, Pieper C, Pickering TG. Anticipatory and residual effects of an active coping task on pre- and post-stress baselines. J Psychosom Res. 1994 Feb;38(2):139-49. doi: 10.1016/0022-3999(94)90087-6.

    PMID: 8189403BACKGROUND

  • Pieper C, Warren K, Pickering TG. A comparison of ambulatory blood pressure and heart rate at home and work on work and non-work days. J Hypertens. 1993 Feb;11(2):177-83. doi: 10.1097/00004872-199302000-00010.

    PMID: 8385178BACKGROUND

  • Gerin W, Pieper C, Pickering TG. Measurement reliability of cardiovascular reactivity change scores: a comparison of intermittent and continuous methods of assessment. J Psychosom Res. 1993 Jul;37(5):493-501. doi: 10.1016/0022-3999(93)90005-z.

    PMID: 8350291BACKGROUND

  • James GD, Pickering TG. The influence of behavioral factors on the daily variation of blood pressure. Am J Hypertens. 1993 Jun;6(6 Pt 2):170S-173S. doi: 10.1093/ajh/6.6.170s.

    PMID: 8347312BACKGROUND

  • Pickering TG, James GD. Determinants and consequences of the diurnal rhythm of blood pressure. Am J Hypertens. 1993 Jun;6(6 Pt 2):166S-169S. doi: 10.1093/ajh/6.6.166s.

    PMID: 8347311BACKGROUND

  • Gerin W, Pieper C, Marchese L, Pickering TG. The multi-dimensional nature of active coping: differential effects of effort and enhanced control on cardiovascular reactivity. Psychosom Med. 1992 Nov-Dec;54(6):707-19. doi: 10.1097/00006842-199211000-00011.

    PMID: 1454965BACKGROUND

  • Landsbergis PA, Schnall PL, Deitz D, Friedman R, Pickering T. The patterning of psychological attributes and distress by "job strain" and social support in a sample of working men. J Behav Med. 1992 Aug;15(4):379-405. doi: 10.1007/BF00844730.

    PMID: 1404353BACKGROUND

  • Gerin W, Pieper C, Levy R, Pickering TG. Social support in social interaction: a moderator of cardiovascular reactivity. Psychosom Med. 1992 May-Jun;54(3):324-36. doi: 10.1097/00006842-199205000-00008.

    PMID: 1620808BACKGROUND

  • Schnall PL, Landsbergis PA, Pieper CF, Schwartz J, Dietz D, Gerin W, Schlussel Y, Warren K, Pickering TG. The impact of anticipation of job loss on psychological distress and worksite blood pressure. Am J Ind Med. 1992;21(3):417-32. doi: 10.1002/ajim.4700210314.

    PMID: 1585951BACKGROUND

  • Schnall PL, Schwartz JE, Landsbergis PA, Warren K, Pickering TG. Relation between job strain, alcohol, and ambulatory blood pressure. Hypertension. 1992 May;19(5):488-94. doi: 10.1161/01.hyp.19.5.488.

    PMID: 1568768BACKGROUND

  • Pickering TG, Schnall PL, Schwartz JE, Pieper CF. Can behavioural factors produce a sustained elevation of blood pressure? Some observations and a hypothesis. J Hypertens Suppl. 1991 Dec;9(8):S66-8.

    PMID: 1795207BACKGROUND

  • James GD, Pickering TG, Laragh JH. Ambulatory blood pressure variation is related to plasma renin activity in borderline hypertensive men. Am J Hypertens. 1991 Jun;4(6):525-8. doi: 10.1093/ajh/4.6.525.

    PMID: 1873004BACKGROUND

  • Pickering TG, Devereux RB, Gerin W, James GD, Pieper C, Schlussel YR, Schnall PL. The role of behavioral factors in white coat and sustained hypertension. J Hypertens Suppl. 1990 Dec;8(7):S141-7.

    PMID: 2095382BACKGROUND

  • de Simone G, Roman MJ, Daniels SR, Mureddu G, Kimball TR, Greco R, Devereux RB. Age-related changes in total arterial capacitance from birth to maturity in a normotensive population. Hypertension. 1997 Jun;29(6):1213-7. doi: 10.1161/01.hyp.29.6.1213.

    PMID: 9180620BACKGROUND

  • de Simone G, Devereux RB, Daniels SR, Mureddu G, Roman MJ, Kimball TR, Greco R, Witt S, Contaldo F. Stroke volume and cardiac output in normotensive children and adults. Assessment of relations with body size and impact of overweight. Circulation. 1997 Apr 1;95(7):1837-43. doi: 10.1161/01.cir.95.7.1837.

    PMID: 9107171BACKGROUND

  • Roman MJ, Pickering TG, Schwartz JE, Pini R, Devereux RB. Relation of arterial structure and function to left ventricular geometric patterns in hypertensive adults. J Am Coll Cardiol. 1996 Sep;28(3):751-6. doi: 10.1016/0735-1097(96)00225-2.

    PMID: 8772767BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesHypertension

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

December 1, 1984

Study Completion

February 1, 1993

Last Updated

May 13, 2016

Record last verified: 2000-04