Interaction Between White Potato Consumption and Meal Timing on Glycemic Response and Appetite in Adults [Experiment 2]

NCT07854938 | Recruiting

• 1 other identifier: REB: 25 - 172 [B]
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. The investigators hypothesize that white potatoes will modulate glycemic response, enhance satiety, and mitigate subsequent meal consumption and overall food intake when compared with meals containing low glycemic carbohydrates. Furthermore, they anticipate that the timing of white potato consumption will yield differential effects, with breakfast consumption exerting a more pronounced impact on satiety and subsequent food intake reduction compared to dinner consumption.

Conditions

Healthy Adult; Appetite; Mealtiming; Glycemic Response

Outcome Measures

Primary Outcomes (3)

• Glycemic Response (Acute Phase)

  Blood glucose (mmol/L). Blood glucose concentrations will be measured using a Dexcom G7 CGM system.

  Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).

• Subjective Appetite

  A visual analogue scale (VAS) with four questions will be administered to assess desire to eat, fullness, hunger, and prospective food consumption. Individual questions will be used to form a composite score. Each VAS will be administered via pen and paper where participants will place an 'X" on the VAS line (100 mm).

  Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).

• Rest-of-day Blood Glucose

  Blood glucose (mmol/L). Rest-of-day blood glucose concentrations will be determined using a Dexcom G7 CGM system.

  Continuous measurements for 24 hours post-treatment consumption.

Secondary Outcomes (5)

• Subjective Emotions

  Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).

• Sleep Quality

  Measured at baseline (0-min); upon awakening

• Rest-of-day and next day Food Intake

  For the rest of the day following test session completion and next day (1 day)

• Next-day Subjective Appetite

  Change from baseline (measured at baseline (0-minute), 30-minute, 60-minute, and 120-minute post-breakfast consumption).

• Food Intake

  Morning-after evening test session (upon waking). Measured at baseline (0-min); upon awakening.

Study Arms (6)

Oven-baked Home Fries

EXPERIMENTAL

Test Treatment

Other: Oven-baked Home Fries

Oven-baked White Russet Potato

EXPERIMENTAL

Test Treatment

Other: Oven-baked White Russet Potato

Oven-baked Fries

EXPERIMENTAL

Test Treatment

Other: Oven-baked Fries

Deep Fried, Quick Serve Fries

EXPERIMENTAL

Test Treatment

Other: Deep Fried, Quick Serve Fries

Oven-baked Cauliflower Veggie Tots

EXPERIMENTAL

Test Treatment

Other: Oven-baked Cauliflower Veggie Tots

No Side

EXPERIMENTAL

Test Treatment

Other: No Side

Interventions

Oven-baked Home Fries OTHER

Oven-baked Home Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal)

Oven-baked Home Fries

Oven-baked White Russet Potato OTHER

Oven-baked White Russet Potato (299 g). Test treatments matched for calories (284 kcal)

Oven-baked White Russet Potato

Oven-baked Fries OTHER

Oven-baked Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal)

Oven-baked Fries

Deep Fried, Quick Serve Fries OTHER

Deep Fried, Quick Serve Fries (108 g; McCain Ltd.). Test treatments matched for calories (284 kcal)

Deep Fried, Quick Serve Fries

Oven-baked Cauliflower Veggie Tots OTHER

Oven-baked Cauliflower Veggie Tots (172 g; Green Giant). Test treatments matched for calories (284 kcal)

Oven-baked Cauliflower Veggie Tots

No Side OTHER

No side control (no caloric contribution).

No Side

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years
• within the healthy body weight range \[body mass index (BMI) between 18.5 - 24.9 kg/m2\].

You may not qualify if:

• have a previous diagnosis of diabetes and gastrointestinal, liver or kidney disease;
• have had a major medical or surgical event within the past 6 months;
• have had any significant weight fluctuation in the past 6-months;
• are taking medication that may influence dependent measures;
• are or have been on a diet within the past 6 months;
• skip breakfast or are unable to consume test treatment food.

Sponsors & Collaborators

• Toronto Metropolitan University: lead

Study Sites (1)

Centre for Urban Centre for Urban Innovation (CUI-109), School of Nutrition, Toronto Metropolitan University

Toronto, Ontario, M5B 2K3, Canada

RECRUITING

Central Study Contacts

Nick Bellissimo, PhD

CONTACT

1 + 4169795000; nick.bellissimo@torontomu.ca

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 22, 2026
• First Posted: October 2, 2026
• Study Start: September 1, 2026
• Primary Completion (Estimated): October 1, 2027
• Study Completion (Estimated): October 1, 2027
• Last Updated: October 2, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)