Effects of Meal Characteristics on Appetite

NCT07178405 | Completed

• 1 other identifier: 2025-02415-01
• Study Type: interventional
• Target: 85
• Locations: 1 country
• Sites: 1

Brief Summary

The overall aim of the study is to determine effects of different meal characteristics on energy intake, eating rate and appetite.

Conditions

Appetite; Obesity and Obesity-related Medical Conditions

Keywords

Appetite; Diet; Intervention; Single meal study

Outcome Measures

Primary Outcomes (2)

• Energy intake

  Energy intake estimated by nutrient calculation of leftover food

  Baseline until 1 hour, or completion of the meal (which ever comes first)

• Eating rate

  Time it takes to eat the study meal until satisfied

  Baseline until 1 hour, or completion of the meal (which ever comes first)

Secondary Outcomes (2)

• Self-reported appetite

  Before, and after the meal (before meal and after 30 minutes, 1hour, 1.5 hours, 2 hours and 4 hours)

• Self-reported prospective energy intake

  From 30 min until midnight or bedtime (which ever comes first)

Study Arms (4)

LL

EXPERIMENTAL

Meal low in energy density, low in ultra-processed food

Other: Meal low in energy density, low in ultra-processed food

LH

EXPERIMENTAL

Meal low in energy density, high in ultra-processed food

Other: Meal low in energy density, high in ultra-processed food

HL

EXPERIMENTAL

Meal high in energy density, low in ultra-processed food

Other: Meal high in energy density, low in ultra-processed food

HH

EXPERIMENTAL

Meal high in energy density, high in ultra-processed food

Other: Meal high in energy density, high in ultra-processed food

Interventions

Meal low in energy density, high in ultra-processed food OTHER

Meal low in energy density, high in ultra-processed food

Also known as: LH

LH

Meal high in energy density, low in ultra-processed food OTHER

Meal high in energy density, low in ultra-processed food

Also known as: HL

HL

Meal high in energy density, high in ultra-processed food OTHER

Meal high in energy density, high in ultra-processed food

Also known as: HH

HH

Meal low in energy density, low in ultra-processed food OTHER

Meal low in energy density, low in ultra-processed food

Also known as: LL

LL

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-64 years
• Body mass index (BMI) 18.5-35.0 kg/m2
• Weight stability the last 3 months +/-5%

You may not qualify if:

• Food allergies, intolerances or preferences preventing consumption of any products included in the study.
• Unable to sufficiently understand written and spoken Swedish or English to provide written consent and understand information and instructions from the study personal.
• Pregnant, lactating or planning a pregnancy during the study period.
• History of stomach or gastrointestinal conditions or major gastrointestinal surgery (Inflammatory bowel disease, Crohn's disease, malabsorption, colostomy, bowel resection, gastric bypass surgery etc.)
• Type 1 diabetes or type 2 diabetes.
• Drug treated thyroid disorder
• - Following any weight reduction program or having followed one during the last 6 months prior to screening.
• Medication for weight reduction purpose effecting appetite or fat absorption (e.g. GLP-1 analogues, orlistat)
• Severe dysfunctional eating behavior based on Three Factor Eating Questionnaire

Sponsors & Collaborators

• Göteborg University: lead

Study Sites (1)

University of Gothenburg

Gothenburg, 40530, Sweden

Location

MeSH Terms

Conditions

Obesity

Interventions

Food, Processed

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Linnea Bärebring, PhD, Associate professor

  Göteborg University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: 2\*2 factorial

Study Record Dates

• First Submitted: August 26, 2025
• First Posted: September 17, 2025
• Study Start: September 29, 2025
• Primary Completion: November 27, 2025
• Study Completion: November 27, 2025
• Last Updated: February 4, 2026

Record last verified: 2026-01

Locations

SE (1)