High-intensity Interval Exercise and Chocolate Milk on Blood Glucose and Cognition

NCT03305107 | Completed

• 1 other identifier: REB2017- 088
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the separate and combined effects of high-intensity interval exercise and chocolate milk on glycemic response, cognitive function, subjective appetite, and salivary cortisol among children aged 9-13 year old children.

Conditions

Glycemic Response; Cognitive Function

Keywords

Child; Exercise; Chocolate milk; Blood glucose; Cognition; Appetite; Emotions; Cortisol

Outcome Measures

Primary Outcomes (4)

• Change from baseline Glycemic Response

  Blood samples will be collected via finger-prick method to assess glycemic response (blood glucose, mmol/L)

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

• Change from baseline verbal declarative memory

  Cognitive function test of verbal declarative memory

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

• Change from baseline working memory

  The n-back test consists of 2 levels, 1-back and 2-back, where letters are presented on the screen one at a time. During the 1-back level, participants need to determine if the presented letter is the same as the one letter presented 1 before it or not (by selected 'match' or 'no match' on the side of the screen) and during 2-back need to do determine if it is the same letter as the one presented 2 letters prior.

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

• Change from baseline executive functioning

  The Stroop test consists of one word appearing on the screen written in either blue, red, yellow or green. There are 24 congruent trials where the presented word is the name of the colour it is written it (i.e. 'red' appearing in the colour red), 24 incongruent trials where the word written is a colour word different from the one it is written in (i.e. 'red' appearing in the colour green), and 10 neutral trials where non-colour words appear (i.e. 'tape' appearing in yellow). The participant is asked to tap the corresponding colour that the word is written in as quickly as possible.

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

Secondary Outcomes (14)

• Change from baseline salivary cortisol response

  baseline (-20 min), and 10 and 30 min post-drink consumption

• Change form baseline Subjective Appetite

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

• Change from baseline aggression

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

• Change from baseline anger

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

• Change from baseline excitement

  baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

Study Arms (4)

Exercise and Chocolate Milk

EXPERIMENTAL

Children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down. Children will then drink 240mL of chocolate milk

Other: Exercise and Chocolate Milk

Exercise and Water

EXPERIMENTAL

Children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down. Children will then drink 240mL of water

Other: Exercise and Water

Sitting and Chocolate Milk

EXPERIMENTAL

Children will quietly sit for 20 minutes Children will then drink 240mL of chocolate milk

Other: Sitting and Chocolate Milk

Sitting and Water

EXPERIMENTAL

Children will quietly sit for 20 minutes Children will then drink 240mL of water

Other: Sitting and Water

Interventions

Exercise and Chocolate Milk OTHER

High intensity interval exercise Chocolate Milk

Exercise and Chocolate Milk

Exercise and Water OTHER

High intensity interval exercise Water

Exercise and Water

Sitting and Chocolate Milk OTHER

Sitting Chocolate Milk

Sitting and Chocolate Milk

Sitting and Water OTHER

Sitting Water

Sitting and Water

Eligibility Criteria

• Age: 9 Years - 13 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• be between 9 and 13 years of age
• be healthy, and have been born at term
• not be taking any medications
• not have allergies to dairy or gluten.

You may not qualify if:

• Food sensitivities, allergies, or dietary restrictions
• Health, learning, emotional, or behavioural problems
• Receiving any medications
• Non-habitual breakfast eater (\<5 days/week)

Sponsors & Collaborators

• Toronto Metropolitan University: lead

Study Sites (1)

School of Nutrition, Ryerson University

Toronto, Ontario, M5B 2K3, Canada

Location

Related Publications (1)

• Kucab M, Bellissimo N, Prusky C, Brett NR, Totosy de Zepetnek JO. Effects of a high-intensity interval training session and chocolate milk on appetite and cognitive performance in youth aged 9-13 years. Eur J Clin Nutr. 2021 Jan;75(1):172-179. doi: 10.1038/s41430-020-00718-z. Epub 2020 Aug 19.

  PMID: 32814852 DERIVED

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise; Water; Sitting Position

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Hydroxides; Alkalies; Inorganic Chemicals; Anions; Ions; Electrolytes; Oxides; Oxygen Compounds; Posture

Study Officials

• Nick Bellissimo, PHD

  School of Nutrition, Ryerson University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Study Director

Study Record Dates

• First Submitted: September 29, 2017
• First Posted: October 9, 2017
• Study Start: July 8, 2017
• Primary Completion: December 31, 2017
• Study Completion: May 31, 2018
• Last Updated: August 10, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)