NCT07333443

Brief Summary

To determine the effects of ingesting caffeine at a dose of 3 mg/kg body mass on pull-up performance and handgrip-related measures in trained climbers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 8, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2025

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 15, 2025

Completed
28 days until next milestone

First Posted

Study publicly available on registry

January 12, 2026

Completed
Last Updated

May 6, 2026

Status Verified

December 1, 2025

Enrollment Period

3 months

First QC Date

December 15, 2025

Last Update Submit

April 30, 2026

Conditions

Keywords

sport climbinggrip strengthpull up strengthcaffeinesport performance

Outcome Measures

Primary Outcomes (7)

  • Pull-up 1RM

    Through study completion, an average of 4 weeks

  • Pull-up strength and power test 1

    Mean and peak velocity will be recorded at 60%, 80%, 90%, 95% and 100% 1RM.

    Through study completion, an average of 4 weeks

  • Pull-up strength and power test 2

    Mean and peak power will be recorded at 60%, 80%, 90%, 95% and 100%1RM.

    Through study completion, an average of 4 weeks

  • Pull-up muscular endurance test

    Using body mass and perform one set of many repetitions as possible until task failure. The total number of repetitions, Vmean, Vpeak, Wmean and Wpeak were recorded.

    Through study completion, an average of 4 weeks

  • Grip endurance in dead-hang.

    Maximum hanging time (MHT) test at an 18-mm edge depth with each hand

    Through study completion, an average of 4 weeks

  • Maximum grip strength in dead-hang

    using the Strength Test (ST), which measures the maximal external load a participant can sustain for 5 seconds while hanging from an 18-mm edge

    Through study completion, an average of 4 weeks

  • Grip rate of force development (RFD).

    measuring the maximal one-hand pull (voluntary contraction) at an 18 mm edge with a force sensor

    Through study completion, an average of 4 weeks

Secondary Outcomes (5)

  • Body composition

    Through study completion, an average of 4 weeks

  • Dietary habits

    Through study completion, an average of 4 weeks

  • Physical activity habits

    Through study completion, an average of 4 weeks

  • Rate of perceived exertion

    Through study completion, an average of 4 weeks

  • Mood states

    Through study completion, an average of 4 weeks

Study Arms (2)

Placebo

PLACEBO COMPARATOR

0 mg/kg of caffeine

Dietary Supplement: Placebo

Caffeine

EXPERIMENTAL

3 mg/kg of caffeine

Dietary Supplement: Acute and moderate dose of caffeine (3 mg/kg body mass)

Interventions

Caffeine supplementation was provide to young male climbers.

Caffeine
PlaceboDIETARY_SUPPLEMENT

Placebo supplementation was provide to young male climbers.

Placebo

Eligibility Criteria

Age18 Years - 35 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy individuals
  • Age between 18 and 40 years
  • At least three months of continuous climbing practice
  • Ability to hang for at least 5 seconds from an 18-mm edge
  • Ability to perform at least one strict body-weight pull-up

You may not qualify if:

  • Any musculoskeletal or medical condition preventing completion of the experimental protocol
  • Participation in less than three training sessions per week or a total training volume \<150 min/week
  • Use of medications or dietary supplements known to affect caffeine metabolism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

Alcalá de Henares, Madrid, 28805, Spain

Location

Study Officials

  • Alberto Pérez López, PhD

    University of Alcala

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Participants, investigators and statistician
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: A triple-blind, randomized, placebo-controlled design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 15, 2025

First Posted

January 12, 2026

Study Start

January 8, 2025

Primary Completion

March 30, 2025

Study Completion

October 30, 2025

Last Updated

May 6, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will share

Locations