Peer-Delivered Behavioral Activation in a CCBHC
Hybrid Effectiveness-Implementation Trial to Evaluate a Scalable, Peer-Delivered Intervention for Depression Among People With Substance Use Disorder in a Certified Community Behavioral Health Clinic
1 other identifier
interventional
250
1 country
1
Brief Summary
Low-income individuals have limited access to evidence-based interventions for mental health. Peer recovery specialists, individuals in recovery from mental health and/or substance use problems, have the potential to increase access to evidence-based interventions for individuals from low-resource communities, particularly when trained and supervised in models that are acceptable and feasible in these communities. This study will examine the effectiveness and implementation potential of a peer-delivered evidence-based intervention (Behavioral Activation) among individuals receiving services from a community-based treatment setting providing integrated physical and behavioral healthcare.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable major-depressive-disorder
Started May 2026
Typical duration for not_applicable major-depressive-disorder
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 21, 2025
CompletedFirst Posted
Study publicly available on registry
October 21, 2025
CompletedStudy Start
First participant enrolled
May 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 15, 2029
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 15, 2029
April 17, 2026
April 1, 2026
2.7 years
July 21, 2025
April 15, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Change in Hamilton Depression Rating Scale
The Hamilton Depression Rating Scale (HAM-D) is a structured interview regarding patients' symptoms of depression and functional impairment. The HAM-D will be administered by research assistants under the supervision of the MPI (Felton) at baseline, post-intervention, 6- and 12-month follow-up. The measure is widely used in depression and substance use treatment studies and has excellent psychometric properties. Nine items are scored 0-4 and 8 items are scored 0-2, with higher scores reflecting greater levels of depressive symptoms. A total score will be calculated by summing each other items. Summed total scores can range from 0-52, with higher values reflecting greater depression.
Baseline, post-intervention (approximately 3 months after baseline), 6- and 12-month follow-up
Secondary Outcomes (2)
Change in Patient Health Questionnaire-9
Baseline, post-intervention (approximately 3 months after baseline), 6- and 12-month follow-up
Change in Short Inventory of Problems
Baseline, post-intervention (approximately 3 months after baseline), 6- and 12-month follow-up
Study Arms (2)
Behavioral Activation
EXPERIMENTALPeer Activate is an adapted behavioral activation (BA) intervention, developed for delivery by peer recovery specialists to reduce rates of depressive symptoms and substance use. BA focuses on increasing positive reinforcement through engaging in adaptive, valued behaviors. BA has been found to be effective in improving substance use outcomes and decreasing depressive symptoms among low-income individuals with SUD. Peer Activate includes 6 weekly sessions with up to 6 additional booster sessions.
Enhanced Treatment as Usual
ACTIVE COMPARATOREnhanced treatment as usual (ETAU) involves peer-delivered non-directive support, including facilitated linkages to care and non evidence-based intervention approaches typically used by peer recovery specialists.
Interventions
Peer Activate is an adapted behavioral activation (BA) intervention, developed for delivery by peer recovery specialists to reduce rates of depressive symptoms and substance use. BA focuses on increasing positive reinforcement through engaging in adaptive, valued behaviors. BA has been found to be effective in improving substance use outcomes and decreasing depressive symptoms among low-income individuals with SUD. Peer Activate includes 6 weekly sessions with up to 6 additional booster sessions.
Peers will deliver non-specific peer services, including linkage to care, general support, and facilitated referrals to external providers as needed.
Eligibility Criteria
You may qualify if:
- Age 18 years old or older
- Report clinically-significant symptoms of depression, as indexed by a score of 8+ on the PHQ-9.
You may not qualify if:
- Active, under treated psychotic symptoms or mania that would interfere with participation in study procedures
- Inability to provide informed consent and/or complete procedures in English
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Detroit Recovery Project INCcollaborator
- Wayne State Universitylead
- University of Maryland, College Parkcollaborator
Study Sites (1)
Detroit Recovery Project
Detroit, Michigan, 48208, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
July 21, 2025
First Posted
October 21, 2025
Study Start
May 1, 2026
Primary Completion (Estimated)
January 15, 2029
Study Completion (Estimated)
January 15, 2029
Last Updated
April 17, 2026
Record last verified: 2026-04