Evaluating the Feasibility of an Interdisciplinary Primary Care-based Intervention to Improve Transitions to Follow-Up Care for Hospitalized Patients With Substance Use Disorders

NCT07575373 | Not Yet Recruiting

• 2 other identifiers: IRB_00195935K23DA062174
• Study Type: interventional
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate the feasibility and preliminary effectiveness of a primary care-based Interdisciplinary Addiction Care Transition (IntACT) team that will meet patients with substance use disorders (SUD) during a medical hospitalization and provide intensive care management, peer support, and interim SUD and medical care after discharge while facilitating a transition to long term community-based treatment.

Conditions

Substance Use Disorders

Outcome Measures

Primary Outcomes (5)

• Care Linkage

  percentage of patients who attend any follow up visit within 14 days of hospital discharge. Assessed using administrative records and patient self-report.

  14 Days

• Retention in Treatment

  Percentage of patients who have attended a medical or substance use treatment appointment within the past 30 days. Assessed at 2 months, 4 months, and 6 months after randomization. Assessed using clinic/administrative records and patient-self-report.

  6 Months

• Intervention Feasibility

  Implementation-related outcomes will be collected from N=20 clinicians who are exposed to the IntACT intervention and IntACT team members, respectively. Implementation outcomes include Feasibility, assessed via the 4-item Feasibility of Intervention measure (range 0-12, higher is more feasible)

  Completed once within 2 weeks of exposure to the intervention

• Intervention Acceptability

  Implementation-related outcomes will be collected from N=20 clinicians who are exposed to the IntACT intervention and IntACT team members, respectively. Implementation outcomes include Acceptability, assessed via the 4-item Acceptability of Intervention measure (range 0-12, higher is more acceptible)

  Completed once within 2 weeks of exposure to the intervention

• Intervention Appropriateness

  Implementation-related outcomes will be collected from N=20 clinicians who are exposed to the IntACT intervention and IntACT team members, respectively. Implementation outcomes include Appropriateness, assessed via the 4-item Intervention Appropriateness Measure (range 0-12, higher is more appropriate)

  Completed once within 2 weeks of exposure to the intervention

Secondary Outcomes (4)

• Time to first follow-up visit, assessed using clinic/administrative records and participant self-report.

  6 Months

• Emergency Department visits and hospitalizations

  6 Months

• Substance use

  6 Months

• Participant quality of life

  6 months

Study Arms (2)

IntACT Intervention

EXPERIMENTAL

Participants randomized to IntACT will receive usual inpatient and outpatient services plus an interdisciplinary addiction care transition team.

Behavioral: IntACT

Usual Care

ACTIVE COMPARATOR

Participants randomized to Usual Care will receive standard of care services routinely available at University of Utah Health.

Behavioral: Usual Care

Interventions

IntACT BEHAVIORAL

Participants randomized to IntACT will receive usual inpatient and outpatient services plus an interdisciplinary addiction care transition team providing: (1) in-hospital discharge planning support, (2) proactive post-discharge outreach and care coordination, (3) intensive care management and peer support, and (4) interim SUD and medical care coordination for up to 4 months post-randomization, with the goal of facilitating transition to longitudinal community-based care.

IntACT Intervention

Usual Care BEHAVIORAL

Participants randomized to Usual Care will receive standard of care services routinely available at University of Utah Health, including inpatient addiction consult services when ordered, discharge planning by hospital medical and social work teams, and referrals/follow-up options based on insurance and patient preference. Usual Care participants will not receive the structured IntACT intervention components provided in the intervention arm, including proactive post-discharge outreach by the IntACT care manager/peer support specialist, intensive care management, dedicated peer navigation, scheduled interdisciplinary team review, or interim addiction/primary care transition services delivered by the IntACT team as part of the study. If a Usual Care participant independently establishes care with SPARC clinic or other services through standard referral pathways, this will be permitted and will be captured as part of outcome assessment.

Usual Care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 18 years and older
• Hospitalized at University of Utah Medical Center (UUMC) for any medical reason, and
• Electronic Health Record (EHR) documented diagnosis of any SUD.

You may not qualify if:

• Currently incarcerated
• Tobacco use as only documented substance use disorder

Sponsors & Collaborators

• Michael Incze: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

University of Utah Medical Center

Salt Lake City, Utah, 84112, United States

Location

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Study Officials

• Michael Incze, MD

  University of Utah

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Michael Incze, MD

CONTACT

801-581-7822; michael.incze@hsc.utah.edu

Ulises Amaton, BA

CONTACT

801-581-7822; ulises.amaton@hsc.utah.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: April 27, 2026
• First Posted: May 8, 2026
• Study Start (Estimated): June 15, 2026
• Primary Completion (Estimated): September 15, 2027
• Study Completion (Estimated): September 15, 2027
• Last Updated: May 8, 2026

Record last verified: 2026-05

Locations

US (1)