Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches
LINCS UP: RCT
3 other identifiers
interventional
144
1 country
1
Brief Summary
This is a 3-arm randomized controlled trial. Participants will be randomized via a maximally tolerated imbalance randomization procedure using NCI's Clinical Trial Randomization Tool with 1:1:1 allocation to each group: in-person peer recovery coaching (PRC) with linkage to recovery resources, telemedicine-based peer recovery coaching with linkage to recovery resources, or usual care. In the PRC arms, PRCs will meet patients at bedside (in person) or via a tablet-based video call (telemedicine). They will assess the participant's state of change, engage in motivational interviewing techniques, and link the participant to community-based recovery resources according to the needs of the participant. They will also schedule and perform follow up calls after the participant is discharged from the ED to provide ongoing support and facilitate re-linkage to recovery resources, if needed. Participants in the usual care arm will be provided with a list of community recovery resources, but there will be no PRC interaction or direct linkage to resources through the study. Follow up visits will take place at 7, 30, and 90 days after enrollment. Most will take place via telephone, but participants will be given the option of an in-person visit if they so desire.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 27, 2023
CompletedFirst Posted
Study publicly available on registry
May 6, 2023
CompletedStudy Start
First participant enrolled
August 16, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
September 30, 2025
CompletedDecember 17, 2025
December 1, 2025
1.1 years
April 27, 2023
December 9, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Change in number of participants with successful linkage to at least one recovery resource
Change in number of participants with successful linkage to at least one recovery resource (formal addiction treatment, Recovery Community Organization (RCO), or harm reduction organization) at 30 days and 90 days after enrollment.
Baseline, 30 and 90 days after enrollment
Secondary Outcomes (11)
Change in Brief Assessment of Recovery Capital (BARC-10)
Baseline, 7, 30, and 90 days after enrollment
Change in number of successful engagements with PRC after ED visit
Baseline, 7, 30, and 90 days after enrollment
Change in number of episodes of re-linkage to recovery resources
Baseline, 7, 30, and 90 days post intervention
Self-reported substance use in last 30 days
Baseline, 30 and 90 days post intervention
Number of fatal overdose events
90 days post intervention
- +6 more secondary outcomes
Study Arms (3)
In-person peer recovery coaching with linkage to recovery resources
EXPERIMENTALPRCs will meet patients at bedside (in person). They will also schedule and perform follow up calls after the participant is discharged from the ED to provide ongoing support and facilitate re-linkage to recovery resources, if needed. Follow-up data collection on day 7, 30, 90 post discharge.
Telemedicine-based peer recovery coaching with linkage to recovery resources
EXPERIMENTALPRCs will meet patients via a tablet-based video call (telemedicine). They will also schedule and perform follow up calls after the participant is discharged from the ED to provide ongoing support and facilitate re-linkage to recovery resources, if needed. Follow-up data collection on day 7, 30, 90 post discharge.
Usual Care
ACTIVE COMPARATORParticipants in the usual care arm will be provided with a list of community recovery resources. No callbacks or re-linkage to recovery resources. Follow-up data collection on day 7, 30, 90 post discharge.
Interventions
Peer recovery coach (PRC) assessment of the participant's state of change, engage in motivational interviewing techniques, and link the participant to community-based recovery resources according to the needs of the participant. They will also schedule and perform follow up calls after the participant is discharged from the ED to provide ongoing support and facilitate re-linkage to recovery resources, if needed.
Participants will be provided with a list of community recovery resources.
Eligibility Criteria
You may qualify if:
- ED patient or hospitalized through the ED within last 24 hours
- Age 18 years or older
- Able to speak and understand English
- Clinically sober, able to provide informed consent
- Score of 3 or greater - "moderate level", "substantial level", or "severe level" of problems related to drug abuse - on Drug Abuse Screening Test (DAST-10).(103, 104)
- Willing to follow study procedures and complete research follow-up calls
- Have at least one reliable contact number
You may not qualify if:
- Medically or psychiatrically unstable as determined by treating physician
- Prisoner or in police custody
- Prior participation in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Emory Universitylead
- Centers for Disease Control and Preventioncollaborator
Study Sites (1)
Grady Memorial Hospital
Atlanta, Georgia, 30303, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Joseph E Carpenter, MD
Emory University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
April 27, 2023
First Posted
May 6, 2023
Study Start
August 16, 2024
Primary Completion
September 30, 2025
Study Completion
September 30, 2025
Last Updated
December 17, 2025
Record last verified: 2025-12
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL
- Time Frame
- Data sharing will be initiated upon written request to the PI and would ultimately be shared via a secure portal such as Microsoft OneDrive. The investigators will make data publicly available within 30 months of completing data collection.
- Access Criteria
- Written request to the PI.
Data sharing will be initiated upon written request to the PI and would ultimately be shared via a secure portal such as Microsoft OneDrive. Deidentified data files, the data dictionary, and the final protocol will be uploaded to the Emory Dataverse, which is a long-term repository offered through a partnership between Emory and the Odum Institute at the University of North Carolina and Chapel Hill. This repository has policies and procedures in place that will provide data access to qualified researchers, fully consistent with federal data sharing policies and applicable laws and regulations. Datasets are uniquely named with a persistent digital object identifier (DOI), and are downloadable directly through a web-based interface. Additional data documentation and de-identified data will be deposited for sharing along with data consistent with applicable laws and regulations. Submitted data will confirm with relevant data and terminology standards.