Effects of Different Volumes of Resistance Training

NCT06449300 | Completed DMC

• 1 other identifier: 2021.11.07
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This study explores the effects of varying volumes of resistance training on body composition, strength, peak power, and muscle thickness in untrained women over eight weeks. A randomized controlled trial involving 45 female college students assessed the outcomes across three groups: low-volume training (LVT) with three weekly sessions, moderate-volume training (MVT) with four weekly sessions, and high-volume training (HVT) with five weekly sessions. Participants were untrained, aged 18-65, and free from cardiovascular diseases or performance-enhancing drugs. The hypothesis suggested that moderate volume training would yield optimal muscle development, considering the potential non-linear dose-response relationship where excessive training might be detrimental. Measurements included body composition, muscle thickness, and peak power through a force platform during vertical jumps. Data analysis focused on changes in muscle thickness, strength, and body composition, with statistical significance set at p \< 0.05. The study aimed to provide insights into how different training volumes affect physiological adaptations in untrained women, potentially guiding fitness regimen optimizations for similar populations.

Conditions

Healthy

Keywords

Strength training; muscle growth

Outcome Measures

Primary Outcomes (4)

• Body height measurements

  A stadiometer is attached to the wall. It has a sliding horizontal headpiece that's adjusted to rest on top of your head. The measurement of height will be conducted using a Mesilife portable stadiometer.

  at baseline and end of 8 week

• Anthropometric measurements

  Bio-impedance body composition analysis system

  at baseline and end of 8 week

• Muscle thickness measurements

  A portable ultrasound scanner will be used to determine muscle thickness. At one location, muscle thickness will be measured: Between the greater trochanter and the lateral epicondyle of the thigh, the thickness of the quadriceps femoris (Vastus lateralis) will be measured at 50%. Ultrasound tests will be done at the start of the study and 8 weeks later, by a researcher blinded to the interventions. All tests were performed in the morning when participants are fasting.

  at baseline and end of 8 week

• Countermovement Jump (CMJ)

  Countermovement Jump (CMJ) values of all participants will be measured. Peak muscle power measures in watts (W) using the Accupeak power2.0 portable force platform system . The measurement frequency of the device was set to 500 Hz. Participants will undrergo a 10-minute warm-up program before completing a CMJ. Participants will be asked to begin a downward movement and jump as high as possible after hearing a tone from the computer.

  at baseline and end of 8 week

Study Arms (3)

low volume (LVT) resistance training

EXPERIMENTAL

3 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed.

Other: Resistance exercise-LVT

moderate volume (MVT) resistance training

ACTIVE COMPARATOR

4 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed.

Other: Resistance exercise-MVT

high volume (HVT) resistance training

ACTIVE COMPARATOR

5 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed.

Other: Resistance exercise-HVT

Interventions

Resistance exercise-LVT OTHER

(low volume training - 3 sessions of 12 exercises per week)

low volume (LVT) resistance training

Resistance exercise-MVT OTHER

(moderate volume training - 4 sessions of 12 exercises per week)

moderate volume (MVT) resistance training

Resistance exercise-HVT OTHER

(high volume training - 5 sessions of 12 exercises per week)

high volume (HVT) resistance training

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult women between ages of 18 -65 years old
• Able to walk independently
• Free of any history of cardiovascular disease
• Untrained (less than 150 min of PA/week)

You may not qualify if:

• Intake of performance-enhancing drugs, anabolic steroids
• Any history of injury, or physiological or physical limitations that could affect the ability to perform training and physical testing in the last year.
• Those who had been RT for more than 2 months in the previous 6 months were excluded.

Sponsors & Collaborators

• Princess Nourah Bint Abdulrahman University: lead
• Kırıkkale University: collaborator

Study Sites (1)

Princess Nourah bint Abdulrahman University

Riyadh, 11671, Saudi Arabia

Location

Related Publications (1)

• Ugurlu D, Gulu M, Yapici H, Yagin FH, Comertpay E, Eroglu O, Afonso J, Aldhahi MI. Dose-response effects of 8-week resistance training on body composition and muscular performance in untrained young women: A quasi-experimental design. Medicine (Baltimore). 2024 Nov 1;103(44):e40322. doi: 10.1097/MD.0000000000040322.

  PMID: 39496043 DERIVED

Study Officials

• Dondu Ugurlu, Phd

  dondusimsek@kku.edu.tr

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Masking Details: a researcher blinded to the interventions
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: June 1, 2024
• First Posted: June 10, 2024
• Study Start: November 11, 2021
• Primary Completion: December 11, 2023
• Study Completion: January 11, 2024
• Last Updated: June 14, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

SA (1)