NCT05729685

Brief Summary

The goal of this intervention study is to compare the adaptations after a 6-week training period between an intense continuous and a high-intensity interval training program performed under iso-effort conditions on aerobic performance parameters in young healthy adults. The main question it aims to answer are if the intense continuous and a high-intensity interval training programs will induce similar adaptations in maximal (VO2max and PTV) and submaximal (critical velocity, lactate threshold parameters and running economy) aerobic performance parameters. Participants will be ere randomly assigned either to an intense continuous training group (CON) or to a high-intensity interval training group (INT). The training program will comprise of 14 training sessions performed over a 6-week period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Sep 2020

Typical duration for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2020

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 10, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 10, 2021

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 26, 2023

Completed
20 days until next milestone

First Posted

Study publicly available on registry

February 15, 2023

Completed
Last Updated

February 15, 2023

Status Verified

February 1, 2023

Enrollment Period

1.3 years

First QC Date

January 26, 2023

Last Update Submit

February 6, 2023

Conditions

Keywords

exercisemaximal oxygen consumptionendurance

Outcome Measures

Primary Outcomes (4)

  • Changes in maximal oxygen consumption

    Maximal oxygen consumption in ml/kg/min

    At the beginning of the training program, the 3rd week of training (after 7 training sessions), and the 7th week after the start of the intervention (after the completion of 6 weeks of training, 14 training sessions)

  • Changes in peak treadmill velocity

    Peak treadmill velocity using a maximal incremental test to exhaustion on a treadmill in km/h

    At the beginning of the training program, the 3rd week of training (after 7 training sessions), and the 7th week after the start of the intervention (after the completion of 6 weeks of training, 14 training sessions)

  • Changes in running velocities at the 1st and the 2nd lactate thresholds

    Running velocities (km/h) at the 1st and the 2nd lactate thresholds by measuring the changes in blood lactate concentration during a maximal incremental test to exhaustion on a treadmill.

    At the beginning of the training program, the 3rd week of training (after 7 training sessions), and the 7th week after the start of the intervention (after the completion of 6 weeks of training, 14 training sessions)

  • Changes in critical velocity

    Critical velocity (km/h) determined by having the participants ran until exhaustion at velocities corresponding to 90, 100, and 110% of peak treadmill velocity. Using linear regression analyses, the relationship between the distance covered at each run and the time to exhaustion was calculated. Τhe slope of the linear regression line was the critical velocity.

    At the beginning of the training program, the 3rd week of training (after 7 training sessions), and the 7th week after the start of the intervention (after the completion of 6 weeks of training, 14 training sessions)

Secondary Outcomes (2)

  • Changes in running economy

    At the beginning of the training program and the 7th week after the start of the intervention (after the completion of 6 weeks of training, 14 training sessions)

  • Changes in running velocity at a blood lactate concentration of 4 mmol/L

    At the beginning of the training program and the 7th week after the start of the intervention (after the completion of 6 weeks of training, 14 training sessions)

Study Arms (2)

Interval training

EXPERIMENTAL

The interval group trained using the interval trainining method.

Other: Interval training

Continuous training

EXPERIMENTAL

The continuous group trained using the continuous training method.

Other: Continuous training

Interventions

The interval training group trained using the interval method. During the exercise sessions the participants ran each bout at an intensity corresponding to 90% of PTV. PTV was used to prescribe the exercise intensity at the INT group. The duration of the running-bouts was equal to ¼ of the individual time to exhaustion at 90% of PTV (determined during the CV testing) followed by passive rest equal to 2/3 of exercise duration. The duration of the exercise-bouts was individualized based on the time to exhaustion at 90% of PTV to reduce the between subject's variability. The participants terminated each exercise session when an RPE value of 17 was reached. Running bout duration and intensity were adjusted after 7 training sessions (during the 3rd week) following a reassessment of the time to exhaustion at 90% of the "new" PTV achieved during mid-testing as a result of training.

Interval training

The continuous group trained using the continuous method. During the training sessions the participants ran with an intensity corresponding to -2,5% of CV until they reported a rating of 17 at the 6-20 Borg's scale. Running velocity was adjusted after 7 training sessions (during the 3rd week) after reassessment of CV. CV was used to determine the exercise intensity in the CONT group to ensure that all individuals would ran at the heavy intensity domain and be able to complete at least 15 min of continuous running, and to minimize the high inter-individual variations in endurance time at intensities near the upper limit of the heavy intensity domain. Using PTV to determine the intensity in the CONT group, would increase the possibility for trainees to exercise at different exercise intensity domains.

Continuous training

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • All participants should have been involved in low intensity continuous training,
  • All participants should have been training 1-3 times per week for 30-45 min for at least three months.

You may not qualify if:

  • Not familiar with aerobic training
  • Any health issues that did not allow participation in regular exercise training.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Physical Education and Sport Science

Komotini, Rodopi, 69100, Greece

Location

MeSH Terms

Conditions

Motor Activity

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: A parallel group research design was used in the present study. Initially, 26 participants (10 males and 16 females), using stratified randomization (gender was the variable of stratification) were randomly assigned (1:1), according to a random-number table, either to an intense continuous training group (CON) or to a high-intensity interval training group (INT).
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

January 26, 2023

First Posted

February 15, 2023

Study Start

September 1, 2020

Primary Completion

December 10, 2021

Study Completion

December 10, 2021

Last Updated

February 15, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share

Locations