Resistance Training With Blood Flow Restriction

NCT05863039 | Completed

• 1 other identifier: 14083P
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy. This study will compare the effects of resistance training associated with blood flow restriction with a regular resistance training program. Findings of this project will provide important information regarding a promising intervention to potentiate muscle performance.

Conditions

Healthy

Keywords

resistance training; strength training; blood flow restriction; motor units; body composition

Outcome Measures

Primary Outcomes (1)

• Force

  Force of the lower leg muscles using a custom made ergometer

  10 sessions (up to 6 weeks)

Secondary Outcomes (1)

• Body composition

  Start and end of the protocol

Study Arms (3)

Group 1

EXPERIMENTAL

Strength training associated with blood flow restriction

Other: Blood flow restriction

Group 2

EXPERIMENTAL

Conventional strength training using high loads

Other: Regular training type 1

Group 3

EXPERIMENTAL

Conventional strength training using low loads

Other: Regular training type 2

Interventions

Blood flow restriction OTHER

Strength training of the lower leg muscles using blood flow restriction

Group 1

Regular training type 1 OTHER

Strength training of the lower leg muscles using high loads

Group 2

Regular training type 2 OTHER

Strength training of the lower leg muscles using low loads

Group 3

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may not qualify if:

• presence of neurological diseases,
• presence of metal implants or joint replacement
• any restriction to perform physical activity
• pregnancy

Sponsors & Collaborators

• University of Oklahoma: lead

Study Sites (1)

University of Oklahoma

Norman, Oklahoma, 73071, United States

Location

MeSH Terms

Interventions

Blood Flow Restriction Therapy

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities

Study Officials

• Hugo Pereira, PhD

  University of Oklahoma

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 17, 2023
• First Posted: May 17, 2023
• Study Start: November 1, 2022
• Primary Completion: May 31, 2025
• Study Completion: April 27, 2026
• Last Updated: May 1, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL

Locations

US (1)