Echocardiographic and Laboratory Findings in Hemodynamic Monitoring of Shocked Patients
Comparison of Echocardiographic and Laboratory Findings in Hemodynamic Monitoring of Shocked Patients
1 other identifier
observational
60
0 countries
N/A
Brief Summary
Shocked patients require prompt and accurate assessment of their hemodynamic status to guide appropriate management. Echocardiography is a valuable tool for assessing cardiac function, while laboratory parameters such as mixed venous oxygen saturation and arterial blood lactate provide insights into tissue perfusion and oxygen metabolism. This study aims to compare echocardiographic findings, including cardiac index, speckle tracking parameters, and tissue Doppler indices, with laboratory findings in the evaluation of hemodynamic monitoring in shocked patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2024
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 6, 2024
CompletedFirst Posted
Study publicly available on registry
April 2, 2024
CompletedStudy Start
First participant enrolled
May 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2026
CompletedApril 2, 2024
March 1, 2024
1.8 years
March 6, 2024
March 30, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Change in Shock Status After Fluid Therapy Based on Echocardiographic Assessment of Fluid Responsiveness
Change in shock status will be assessed 24 hours after initiation of fluid therapy by echocardiographic evaluation of cardiac index in liters per minute per square meter (L/min/m2).
24 hours
Interventions
Measuring echocardiographic parameters (cardiac index, speckle tracking, tissue Doppler indices)
Eligibility Criteria
Adult patients (age \>18 years) presenting with shock admitted to the intensive care unit.
You may qualify if:
- Patients diagnosed with shock based on clinical criteria (e.g., hypotension, signs of tissue hypoperfusion) requiring hemodynamic monitoring.
- Patients age \> 18 year old.
You may not qualify if:
- Patients with pre-existing cardiac conditions affecting echocardiographic parameters, those receiving mechanical circulatory support.
- Patients with contraindications to echocardiography or blood sampling.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Jardin F, Fourme T, Page B, Loubieres Y, Vieillard-Baron A, Beauchet A, Bourdarias JP. Persistent preload defect in severe sepsis despite fluid loading: A longitudinal echocardiographic study in patients with septic shock. Chest. 1999 Nov;116(5):1354-9. doi: 10.1378/chest.116.5.1354.
PMID: 10559099BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Dina Ahmed
Assiut University
- STUDY CHAIR
Mohamed Maghraby
Assiut University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
March 6, 2024
First Posted
April 2, 2024
Study Start
May 1, 2024
Primary Completion
March 1, 2026
Study Completion
May 1, 2026
Last Updated
April 2, 2024
Record last verified: 2024-03
Data Sharing
- IPD Sharing
- Will not share