Key Insights

Highlights

Success Rate

86% trial completion

Published Results

15 trials with published results (6%)

Research Maturity

114 completed trials (48% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

7.5%

18 terminated out of 239 trials

Success Rate

86.4%

-0.1% vs benchmark

Late-Stage Pipeline

11%

26 trials in Phase 3/4

Results Transparency

13%

15 of 114 completed with results

Key Signals

15 with results86% success18 terminated

Data Visualizations

Phase Distribution

113Total
Not Applicable (69)
P 1 (6)
P 2 (12)
P 3 (10)
P 4 (16)

Trial Status

Completed114
Unknown44
Recruiting30
Not Yet Recruiting20
Terminated18
Active Not Recruiting5

Trial Success Rate

86.4%

Benchmark: 86.5%

Based on 114 completed trials

Clinical Trials (239)

Showing 20 of 20 trials
NCT04964492Completed

Assessment of the Hemodynamic Effect of Hydroxocabalamin in Refractory Vasodilatory Shock

NCT07644494CompletedPrimary

Distensibility Index of Inferior Vena Cava in Assessing Fluid Responsiveness: The Impact of Spontaneous Respiratory Effort

NCT07537621RecruitingPrimary

Right Ventriculo-Arterial Coupling During Fluid Loading in ICU Patients

NCT07637240Not Yet RecruitingPrimary

CRUISE System in Flight

NCT07529990Completed

Impact of Sodium Profiling During Haemodialysis on Haemodynamic Tolerance and Sonographic Extravascular Lung Water in Shocked Patients With Acute Kidney Injury

NCT07616817Enrolling By Invitation

Delphi Septic Shock: Sub-phenotypes Using Point-of-Care Ultrasound in Patients With Septic Shock

NCT07609095Recruiting

Peripheral pULSe Assessment and Arterial pRessure (PULSAR)

NCT03553069Completed

Simple Observational Critical Care Studies

NCT05054452Not ApplicableCompleted

Predicting Fluid Responsiveness in Mechanically Ventilated Critically Ill Children Using Transthoracic Echocardiography

NCT07546656Recruiting

Prediction of Fluid Responsiveness Using the Femoral Vein-to-Artery Diameter Ratio

NCT06930235Not ApplicableCompletedPrimary

Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors

NCT06713668Not ApplicableActive Not Recruiting

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

NCT07547020Not Yet Recruiting

Hemodynamic Profiles and Macro-Microcirculatory Coherence in Liver Transplantation: an Integrative Approach in the Immediate Postoperative Period

NCT07467798Not ApplicableNot Yet RecruitingPrimary

A Proof-of-concept Study of Ultrasound Stimulation of the Neck to Enhance Anti-shock Efficacy

NCT06460519RecruitingPrimary

The Prevalence of the Aortic to Radial Pressure Gradient in States of Shock, Outside the Context of Cardiac Surgery, a Prospective Study

NCT05092165Phase 2Completed

Methylene Blue for the Prevention of Hypotension During Hemodialysis

NCT01802099Not ApplicableCompleted

Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines

NCT05209737Not ApplicableTerminated

Trendelenburg as a First-line Intervention in Critically Ill, Sedated, Invasively Mechanically Ventilated, Hypotensive Patients

NCT07020637RecruitingPrimary

Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance

NCT07519226Not ApplicableCompletedPrimary

Effectiveness and Safety of Penehyclidine Hydrochloride for Improving Microcirculatory Dysfunction in Critically Ill Children

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