NCT06642259

Brief Summary

The goal of this study To check correlation between triglyceride glucose (TyG) index and residual SYNTAX score (RSS) in STEMI patients undergoing PPCI. 2\. Impact of both TyG index and RSS in STEMI patients undergoing PPCI on LV EF recovery after 3 months using LV speckle tracking. 3\. Impact of RSS and TyG index in STEMI patients undergoing PPCI on short term MACE at 3 months duration.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
185

participants targeted

Target at P50-P75 for all trials

Timeline
32mo left

Started Dec 2024

Longer than P75 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress36%
Dec 2024Dec 2028

First Submitted

Initial submission to the registry

September 18, 2024

Completed
27 days until next milestone

First Posted

Study publicly available on registry

October 15, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

December 1, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Expected
Last Updated

October 15, 2024

Status Verified

October 1, 2024

Enrollment Period

1 year

First QC Date

September 18, 2024

Last Update Submit

October 12, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • 1. To check correlation between triglyceride glucose (TyG) index and residual SYNTAX score (RSS) in STEMI patients undergoing PPCI

    1\. To check correlation between triglyceride glucose (TyG) index and residual SYNTAX score (RSS) in STEMI patients undergoing PPCI.

    baseline

Interventions

ECHO

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All patients with STEMI and will undergo PPCI and fulfilling our inclusion criteria over a period of 6 months will be enrolled in our study.

You may qualify if:

  • All patient who are between 18 and 80 years old who present to our hospital (Assiut university heart hospital) with STEMI and eligible for primary PCI as treatment of choice according to guidelines, will be included in our study.

You may not qualify if:

  • Patient who refuse to undergo revasculariztion using primary PCI.
  • Patient who will die before withdraw of laboratory blood sample.
  • Patient with previous PCI and/or CABG.
  • Patient with underlying co-morbidity with life expectancy less than 1 year (end stage liver disease, end stage renal disease on regular dialysis, active malignancy).
  • Patient with failed canalization of infarct related artery.
  • Patient referred to CABG after angiography.
  • Patient who is unconscious after cardiac arrest .

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial InfarctionMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Salwa Roshdy, Pro

    Assiut University

    STUDY DIRECTOR

Central Study Contacts

Mohammad Medhat, MD student

CONTACT

Amir Khalifa, DR

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Lecturer

Study Record Dates

First Submitted

September 18, 2024

First Posted

October 15, 2024

Study Start

December 1, 2024

Primary Completion

December 1, 2025

Study Completion (Estimated)

December 1, 2028

Last Updated

October 15, 2024

Record last verified: 2024-10