Success Metrics

Clinical Success Rate
91.8%

Based on 101 completed trials

Completion Rate
92%(101/110)
Active Trials
93(31%)
Results Posted
10%(10 trials)
Terminated
9(3%)

Phase Distribution

Ph phase_4
2
1%
Ph early_phase_1
1
0%
Ph not_applicable
51
17%
Ph phase_1
34
11%
Ph phase_2
31
10%
Ph phase_3
6
2%

Phase Distribution

35

Early Stage

31

Mid Stage

8

Late Stage

Phase Distribution125 total trials
Early Phase 1First-in-human
1(0.8%)
Phase 1Safety & dosage
34(27.2%)
Phase 2Efficacy & side effects
31(24.8%)
Phase 3Large-scale testing
6(4.8%)
Phase 4Post-market surveillance
2(1.6%)
N/ANon-phased studies
51(40.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.2%

101 of 120 finished

Non-Completion Rate

15.8%

19 ended early

Currently Active

93

trials recruiting

Total Trials

297

all time

Status Distribution
Active(108)
Completed(101)
Terminated(19)
Other(69)

Detailed Status

Completed101
Recruiting72
unknown66
Active, not recruiting21
Not yet recruiting14
Withdrawn10

Development Timeline

Analytics

Development Status

Total Trials
297
Active
93
Success Rate
91.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.8%)
Phase 134 (27.2%)
Phase 231 (24.8%)
Phase 36 (4.8%)
Phase 42 (1.6%)
N/A51 (40.8%)

Trials by Status

withdrawn103%
recruiting7224%
suspended31%
not_yet_recruiting145%
unknown6622%
completed10134%
enrolling_by_invitation10%
active_not_recruiting217%
terminated93%

Recent Activity

Clinical Trials (297)

Showing 20 of 297 trialsScroll for more
NCT06287944Phase 1

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Recruiting
NCT03779854Phase 2

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Recruiting
NCT06034470Phase 1

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Active Not Recruiting
NCT06871410Phase 1

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Recruiting
NCT06475976

Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

Recruiting
NCT06013423Phase 2

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Recruiting
NCT06863402Phase 2

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Recruiting
NCT06242834Phase 2

Pembrolizumab and Tazemetostat to Overcome Immune Tolerance Following ASCT or CAR T-cell Therapy in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

Active Not Recruiting
NCT06164275Phase 2

Pembrolizumab Followed by Chemotherapy for the Treatment of Patients With Classical Hodgkin Lymphoma

Active Not Recruiting
NCT02068794Phase 1

MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Active Not Recruiting
NCT06304233

The Protein Disrupted in Schizophrenia 1 (DISC1) as a Novel Biomarker for Cardiac Disease

Active Not Recruiting
NCT06249191Phase 1

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Recruiting
NCT06043713Phase 1

Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations

Recruiting
NCT06232044Phase 1

Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT06876714Phase 3

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Recruiting
NCT06203912Phase 1

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Completed
NCT03179904Phase 2

TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer

Completed
NCT06815003Phase 2

Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

Recruiting
NCT06815029Phase 1

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Recruiting
NCT06225427Phase 1

Gilteritinib for the Treatment of ALK NSCLC

Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
297