Fluid Resuscitation In Trauma: What Are The Best Strategies And Fluids?
1 other identifier
observational
100
1 country
1
Brief Summary
Illustration of the differential effects of commonly used resuscitation fluids, including isotonic crystalloids, natural and artificial colloids, hypertonic and hyperoncotic solutions to prevent the cellular injury through wiser resuscitation in traumatic patient . The ideal resuscitation strategy for multiply injured patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Aug 2022
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2022
CompletedFirst Submitted
Initial submission to the registry
February 1, 2023
CompletedFirst Posted
Study publicly available on registry
February 22, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2025
CompletedFebruary 22, 2023
February 1, 2023
2.7 years
February 1, 2023
February 11, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Haemodynamic stability
Make the shocked patient haemodynamically stable , systolic blood pressure \>90
1day
Study Arms (2)
Shocked patients who take crystalloids
Impact of crystalloids on shocked patients in trauma
Shocked patients who take colloids
Impact of colloids on shocked patients in trauma
Eligibility Criteria
Impact of resuscitation fluid (crystalloid,colloids) on shocked patients
You may qualify if:
- The present study will be conducted on shocked patients with multiple trauma of both genders and had 12 years old or more.
You may not qualify if:
- patients who are less than 12 years old,haemodynamically stable or with end stage chronic disease . Furthermore ,patients refusing study will be excluded.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut University
Asyut, Egypt
Related Publications (2)
Finfer S, Liu B, Taylor C, Bellomo R, Billot L, Cook D, Du B, McArthur C, Myburgh J; SAFE TRIPS Investigators. Resuscitation fluid use in critically ill adults: an international cross-sectional study in 391 intensive care units. Crit Care. 2010;14(5):R185. doi: 10.1186/cc9293. Epub 2010 Oct 15.
PMID: 20950434RESULTShackford SR, Mackersie RC, Holbrook TL, Davis JW, Hollingsworth-Fridlund P, Hoyt DB, Wolf PL. The epidemiology of traumatic death. A population-based analysis. Arch Surg. 1993 May;128(5):571-5. doi: 10.1001/archsurg.1993.01420170107016.
PMID: 8489391RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mohamed Abdelatif
Assiut University
- PRINCIPAL INVESTIGATOR
Asmaa Elkafafy
Alexandria University
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant lacturer
Study Record Dates
First Submitted
February 1, 2023
First Posted
February 22, 2023
Study Start
August 1, 2022
Primary Completion
April 1, 2025
Study Completion
October 1, 2025
Last Updated
February 22, 2023
Record last verified: 2023-02
Data Sharing
- IPD Sharing
- Will not share
Not decided till now