The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism

NCT06330649 | Completed DMC

• 1 other identifier: 2024-0095
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this protocol is to investigate the effect of consumption of a commercially available energy drink beverage on blood pressure, heart rate, and energy metabolism

Conditions

Cardiovascular Diseases; Hypertension; Diet

Keywords

Energy metabolism; Arterial blood pressure; heart rate

Outcome Measures

Primary Outcomes (3)

• Peripheral blood pressure in millimeters of mercury

  blood pressure will be measured on the upper arm using standard procedures that are done in a doctors office.

  baseline & 30, 60, 90, 120 min following beverage consumption

• Oxygen consumption milliliters per kilogram of body weight per minute

  This will be assessed using a metabolic cart to measure the amount of oxygen that is consumed by the body.

  baseline & 30, 60, 90, 120 min following beverage consumption

• Heart rate in beats per minute

  Heart will be measured using an electrocardiogram procedures that are done in a doctors office.

  baseline & 30, 60, 90, 120 min following beverage consumption

Study Arms (2)

Energy Drink

EXPERIMENTAL

A commercially available caffeine drink containing 200 mgs of caffeine.

Dietary Supplement: Energy Drink

Water

PLACEBO COMPARATOR

This will be 12 fl oz of commercially available water .

Other: Water Control

Interventions

Energy Drink DIETARY_SUPPLEMENT

This is a commercially available energy drink

Energy Drink

Water Control OTHER

This is a commercially available bottled water

Water

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Between ages 18-30
• Must be free of reported cardiovascular, respiratory, and metabolic diseases.
• Must be caffeine naïve
• Must be fasted

You may not qualify if:

• Food allergies
• pregnant women
• Breast feeding women
• Individuals with cardiac, cardiovascular, respiratory, metabolic, and/or neurological disorders
• taking any prescription vasoactive medications
• allergies to spandex/lycra

Sponsors & Collaborators

• The University of Texas at Arlington: lead

Study Sites (1)

UT Arlington - Science and Engineering Innovation and Research Building

Arlington, Texas, 76019, United States

Location

MeSH Terms

Conditions

Cardiovascular Diseases; Hypertension

Interventions

Energy Drinks

Condition Hierarchy (Ancestors)

Vascular Diseases

Intervention Hierarchy (Ancestors)

Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Robert M Brothers, PhD

  University of Texas at Arlington

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Individuals will be randomly assigned to either an experimental or a control condition.

Study Record Dates

• First Submitted: March 12, 2024
• First Posted: March 26, 2024
• Study Start: January 1, 2024
• Primary Completion: September 1, 2024
• Study Completion: September 1, 2024
• Last Updated: April 1, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)