NCT06961981

Brief Summary

The purpose of this study is to test a 12-week vinyasa yoga (flow yoga) intervention via Zoom. This program will be for 30 individuals with high blood pressure. 15 will receive the intervention and 15 will follow their usual routine. The investigators will determine if this vinyasa yoga program is feasible and acceptable in this population. Investigators will measure and compare blood pressure and other health responses such as physical health and well-being before and after participants complete the intervention or usual care period. The investigators hope to demonstrate that vinyasa yoga is a good option to improve heart health in people with high blood pressure. Primary Objective - Examine the feasibility, acceptability, and preliminary efficacy of a 12-wk remotely-delivered vinyasa yoga intervention (3 x per week) on cardiovascular (CV) health in adults with hypertension (HTN).

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable hypertension

Timeline
Completed

Started Aug 2025

Shorter than P25 for not_applicable hypertension

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 8, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

August 1, 2025

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
Last Updated

August 17, 2025

Status Verified

April 1, 2025

Enrollment Period

9 months

First QC Date

April 29, 2025

Last Update Submit

August 12, 2025

Conditions

HypertensionCardiovascular Diseases

Keywords

Yogavinyasa yoga

Outcome Measures

Primary Outcomes (1)

  • Change in Carotid-Femoral Pulse Wave Velocity

    Change from baseline to 12 weeks. Measure of central arterial stiffness (meters/second) measured by oscilometiric pulse wave velocity. A value of 10 m/s and above is classified as an unfavorable value.

    Baseline to 12 weeks

Secondary Outcomes (29)

  • Change in systolic blood pressure

    Baseline to 12 weeks

  • Change in diastolic blood pressure

    Baseline to 12 weeks

  • Change in augmentation pressure

    Baseline to 12 weeks

  • Change in augmentation index

    Baseline to 12 weeks

  • Change in mean heart rate

    Baseline to 12 weeks

  • +24 more secondary outcomes

Study Arms (2)

Vinyasa Yoga

EXPERIMENTAL

Participants will complete a 12-week, remotely-delivered intervention with three 60-minute vinyasa yoga sessions per week via Zoom, following an adapted Journey into Power yoga sequence by Baron Baptiste. The sessions will incorporate three mind-body components of yoga: through physical yoga poses, mindfulness, and breathing.

Behavioral: Vinyasa Yoga

Standard Routine

NO INTERVENTION

Standard usual routine for 12 weeks

Interventions

Vinyasa YogaBEHAVIORAL

Each yoga session will begin with 2 minutes of integration poses (Child's Pose, Downward Facing Dog, Ragdoll, and Mountain Pose), followed by \~20 minutes of Sun Salutations A and B (up to 5 of each). The Standing Series, lasting \~25 minutes, will include various standing and balancing poses from the Journey into Power sequence. Seated and supine stretches (including seated stretches, a yoga inversion, a reclined twist) will last \~8 minutes, and the session will conclude with 5 minutes of Savasana for final relaxation.

Also known as: Flow Yoga
Vinyasa Yoga

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Individuals with a resting systolic BP \>130 mmHg

You may not qualify if:

  • Report currently meeting aerobic activity guidelines (150 min/wk)
  • Practice yoga regularly (1 or more day/wk in the past month)
  • Have physical limitations or a major medical condition contraindicating yoga or assessments
  • Have uncontrolled HTN (systolic BP 160 mmHg or diastolic BP 100 mmHg)
  • Are currently pregnant or planning to become pregnant within 6 months
  • Are not on a stable dose of medications that could affect study outcomes
  • Are concurrently enrolled in another lifestyle program
  • No vulnerable populations will be included

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

West Virginia University

Morgantown, West Virginia, 26506, United States

RECRUITING

MeSH Terms

Conditions

HypertensionCardiovascular Diseases

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Officials

  • Bethany Barone Gibbs, PhD

    West Virginia University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Alexis Thrower, MS

CONTACT

724-814-1895ant00017@hsc.wvu.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD

Study Record Dates

First Submitted

April 29, 2025

First Posted

May 8, 2025

Study Start

August 1, 2025

Primary Completion

May 1, 2026

Study Completion

May 1, 2026

Last Updated

August 17, 2025

Record last verified: 2025-04

Locations

US(1)