Light Therapy for Internet Gaming Disorder

NCT06165549 | Completed

• 1 other identifier: Internet Gaming Disorder
• Study Type: interventional
• Target: 104
• Locations: 1 country
• Sites: 2

Brief Summary

This project aims to investigate (1) the efficacy of light therapy on internet gaming disorder (IGD); (2) the underlying neural mechanisms of such efficacy

Conditions

Internet Gaming Disorder; Light Therapy

Outcome Measures

Primary Outcomes (5)

• changes in IGD severity

  The scores of IGD severity will be assessed with the internet addiction test for internet gaming disorder.

  baseline , within one day after intervention, and 4-week after intervention

• changes in weekly gaming time

  weekly gaming time will be recorded by Software.

  baseline and within 1 day after intervention

• changes in withdrawal symptoms

  The scores of withdrawal symptoms will be assessed with the mood and physical symptoms scale.

  baseline and within 1 day after intervention

• change of BOLD signals

  Task-based fMRI and resting state fMRI.

  baseline and within 1 day after intervention

• changes in craving

  Craving will be assessed using a Visual Analog Scale during a cue-reactivity task.

  baseline and within 1 day after intervention

Secondary Outcomes (6)

• changes in gaming-related compulsive behaviors

  baseline and within 1 day after intervention

• changes in gaming-related compulsive thoughts

  baseline and within 1 day after intervention

• changes in the quality and patterns of sleep

  baseline and within 1 day after intervention

• changes in the severity of depression

  baseline and within 1 day after intervention

• changes in the severity of anxiety

  baseline and within 1 day after intervention

Study Arms (3)

Light therapy

EXPERIMENTAL

about 30 individuals with internet gaming disorder will be randomly assigned to the light therapy group

Other: Light therapy

Light placebo

PLACEBO COMPARATOR

about 30 individuals with internet gaming disorder will be randomly assigned to the light placebo group

Other: Light placebo therapy

EABM training group

OTHER

about 30 individuals with internet gaming disorder will be randomly assigned to the EABM training group

Other: Emotion Bias Modification Training

Interventions

Light therapy OTHER

The light therapy will be administered by custom-made light boxes (LED) with adjustable brightness. The light intensity will be set at 5000 Lux. The intervention will consist of daily exposure for 30 minutes in the morning. The whole intervention includes 14 days.

Light therapy

Light placebo therapy OTHER

The light placebo intervention will be administered by custom-made light boxes (LED) with adjustable brightness. The light intensity will be set at less than 200 Lux. The intervention will consist of daily exposure for 30 minutes in the morning. The whole intervention includes 14 days.

Light placebo

Emotion Bias Modification Training OTHER

The training aims at associating gaming pictures with negative words and pictures of healthy activities with positive words. Gaming pictures are always presented with a pair of negative words. Pictures of healthy activities are always presented with a pair of positive words. Each picture is presented with a fixed pair of words. Participants will be instructed to select one word to get the most monetary reward. Specifically, selecting a fixed word of the word-pair will be associated with a high probability (eighty percent) of getting a monetary reward and a low probability (twenty percent) of no reward, and probabilities will be reversed for the other word. Each training run will comprise 100 gaming picture trials and 100 healthy-activity picture trials, presented in a pseudo-randomized order. Participants will receive two training runs every day. The whole training includes 14 days.

EABM training group

Eligibility Criteria

• Age: 18 Years - 28 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• the 5th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5 ) recommended diagnosis of Internet gaming disorder;
• the scores of the Young-Internet addiction Test ≥ 50;
• playing internet games ≥15 h/week for ≥1 year

You may not qualify if:

• current or history of psychiatric or neurological illness;
• current or history of use of illegal substances and other addictions;
• current use of psychotropic medications ;
• any history of head trauma, presence of metal in the body or other contraindication to functional MRI scanning;
• photosensitivity disorders, such as systemic lupus erythematosus and chronic actinic dermatitis.

Sponsors & Collaborators

• Jinan University Guangzhou: lead

Study Sites (2)

South China Normal University

Guangzhou, Guangdong, 510000, China

Location

Jinan University

Guangdong, Guangzhou, 510000, China

Location

MeSH Terms

Conditions

Internet Addiction Disorder

Interventions

Phototherapy

Condition Hierarchy (Ancestors)

Technology Addiction; Behavior, Addictive; Compulsive Behavior; Impulsive Behavior; Behavior

Intervention Hierarchy (Ancestors)

Therapeutics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor Tao

Study Record Dates

• First Submitted: November 27, 2023
• First Posted: December 11, 2023
• Study Start: December 16, 2023
• Primary Completion: June 15, 2024
• Study Completion: June 15, 2024
• Last Updated: July 24, 2024

Record last verified: 2024-07

Locations

CN (2)