Emotional Association Bias Modification Training in Individuals With IGD

NCT04068064 | Completed DMC

• 1 other identifier: EABMT_IGD
• Study Type: interventional
• Target: 87
• Locations: 1 country
• Sites: 1

Brief Summary

This project aims to investigate (1) the efficacy of emotional association bias modification (EABM) training on internet gaming disorder (IGD); (2) the underlying neural mechanisms of such efficacy

Conditions

Internet Gaming Disorder

Outcome Measures

Primary Outcomes (3)

• Changes in gaming-related positive emotional association biases (EAB)

  The gaming-related positive EAB will be assessed in a priming task. In the task, participants will be instructed to judge the emotional valence of positive or negative words following gaming pictures or healthy-activity pictures. Gaming-related positive EAB will be calculated by determining differences in reaction times (RTs; RTs (negative-word) minus RTs (positive-word)) in response to words following gaming pictures

  baseline , the 1st day after training

• Changes in gaming-related compulsive thoughts

  the scores of gaming-related compulsive thoughts will be assessed with the Yale-Brown Obsessive-Compulsive Scale modified for internet gaming disorder. The range of the score concerning gaming-related compulsive thoughts of this scale is from 0 to 20. Higher scores means more gaming-related compulsive thoughts.

  baseline, the 1st week after training, the 2nd week after training, the 3rd week after training, the 4th week after training, the 6th week after training, the 8th week after training

• Changes in gaming-related compulsive behaviors

  the scores of gaming-related compulsive behaviors will be assessed with the Yale-Brown Obsessive-Compulsive Scale modified for internet gaming disorder. The range of the score concerning gaming-related compulsive behaviors of this scale is from 0 to 20. Higher scores means more gaming-related compulsive behaviors.

  baseline, the 1st week after training, the 2nd week after training, the 3rd week after training, the 4th week after training, the 6th week after training, the 8th week after training

Secondary Outcomes (4)

• Changes in positive healthy-activity-related EAB

  baseline and the 1st day after training

• Changes in IGD severity

  baseline, the 4th week after training, the 8th week after training

• Changes in weekly gaming time

  baseline, the 1st week after training, the 2nd week after training, the 3rd week after training, the 4th week after training, the 6th week after training, the 8th week after training

• Changes in craving

  baseline , the 1st day after training

Study Arms (2)

EABM training group

EXPERIMENTAL

about 40 individuals with IGD will be randomly assigned to the EABM training group

Procedure: EABM training

Control training group

PLACEBO COMPARATOR

about another 40 individuals with IGD will be randomly assigned to the control training group

Procedure: sham training

Interventions

EABM training PROCEDURE

The training aims at associating gaming pictures with negative words and pictures of healthy activities with positive words. Gaming pictures are always presented with a pair of negative words. Pictures of healthy activities are always presented with a pair of positive words. Each picture is presented with a fixed pair of words. Participants will be instructed to select one word to get the most monetary reward. Specifically, in response to each gaming picture, selecting one word will have a 70% chance to get a monetary reward and the other word will have a 30% chance to get a monetary reward. A similar rationale applies to the pictures of healthy activities. The reward setting will help consolidate target associations. Each training session includes 300 times/trials of each type of association, presented in pseudorandom way. The whole training includes 6 training sessions. Participants will receive one training session every days.

EABM training group

sham training PROCEDURE

In the control group, neutral words instead of emotional words are used. All other settings are the same with those in the intervention group

Control training group

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• the 5th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5 ) recommended diagnosis of Internet gaming disorder :
• the scores of the 9 items of DSM-5 recommended diagnosis for Internet gaming disorder ≥ 5.
• engagement in popular Internet games (e.g. Arena of Valor, League of Legends and Player Unknown's Battle Grounds) for over 20 hours per week for a minimum of 12 months.
• the scores of the Young-Internet addiction Test ≥ 50

You may not qualify if:

• current or history of use of illegal substances and other addictions;
• current or history of psychiatric or neurological illness;
• current use of psychotropic medications.

Sponsors & Collaborators

• Beijing Normal University: lead

Study Sites (1)

State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University

Beijing, Beijing Municipality, 100875, China

Location

Related Publications (2)

• Snagowski J, Wegmann E, Pekal J, Laier C, Brand M. Implicit associations in cybersex addiction: Adaption of an Implicit Association Test with pornographic pictures. Addict Behav. 2015 Oct;49:7-12. doi: 10.1016/j.addbeh.2015.05.009. Epub 2015 May 16.

  PMID: 26026385 BACKGROUND

• Wu L, Xu J, Song K, Zhu L, Zhou N, Xu L, Liu G, Wang Z, Wang R, Qin S, Fang X, Zhang J, Potenza MN. Emotional bias modification weakens game-related compulsivity and reshapes frontostriatal pathways. Brain. 2022 Dec 19;145(12):4210-4221. doi: 10.1093/brain/awac267.

  PMID: 35861265 DERIVED

MeSH Terms

Conditions

Internet Addiction Disorder

Condition Hierarchy (Ancestors)

Technology Addiction; Behavior, Addictive; Compulsive Behavior; Impulsive Behavior; Behavior

Study Officials

• Jintao Zhang, phD

  Beijing Normal University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: the grouping is blind to both participants and the investigator
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: a randomized, between-subject design, including an intervention group and a control group

Study Record Dates

• First Submitted: August 20, 2019
• First Posted: August 28, 2019
• Study Start: August 23, 2019
• Primary Completion: February 28, 2020
• Study Completion: February 28, 2020
• Last Updated: July 5, 2022

Record last verified: 2022-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: 1 year after the publication of related paper , for 3 years
• Access Criteria: By contacting the principal investigator. Email : zhangjintao@bnu.edu.cn

Locations

CN (1)