NCT05039814

Brief Summary

The research aimed to predict postoperative acute kidney injury in patients with acute type A aortic dissection preliminarily by exploring the correlation of preoperative cystatin C level and incidence of postoperative acute kidney injury and combining with relevant risk factors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
249

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2021

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2021

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

September 1, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 10, 2021

Completed
Last Updated

August 3, 2023

Status Verified

August 1, 2021

Enrollment Period

8 months

First QC Date

September 1, 2021

Last Update Submit

August 1, 2023

Conditions

Aortic DissectionAcute Kidney Injury

Outcome Measures

Primary Outcomes (1)

  • postoperative acute kidney injury

    YES; NO

    From date of operation until the date of acute kidney injury or date of death from any cause, whichever came first, assessed up to 30 days.

Study Arms (2)

AKI

patients suffered postoperative acute kidney injury

Other: postoperative acute kidney injury

Non-AKI

patients did not suffer postoperative acute kidney injury

Other: none postoperative acute kidney injury

Interventions

postoperative acute kidney injuryOTHER

patients suffered postoperative acute kidney injury

AKI
none postoperative acute kidney injuryOTHER

patients did not suffered postoperative acute kidney injury

Non-AKI

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients sufferred acute type A aortic dissection

You may qualify if:

  • years old
  • Acute type A aortic dissection diagnosed by CT angiography

You may not qualify if:

  • History of chronic kidney disease
  • History of cardiovascular operation
  • Pregnancy status

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Qilu Hospital of Shandong University

Jinan, Shandong, 250012, China

Location

MeSH Terms

Conditions

Aortic DissectionAcute Kidney Injury

Condition Hierarchy (Ancestors)

Dissection, Blood VesselAneurysmVascular DiseasesCardiovascular DiseasesAcute Aortic SyndromeAortic DiseasesRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Officials

  • Xin Zhao

    Department of cardiac surgery, Qilu Hospital, Shandong University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 1, 2021

First Posted

September 10, 2021

Study Start

October 1, 2020

Primary Completion

June 1, 2021

Study Completion

August 15, 2021

Last Updated

August 3, 2023

Record last verified: 2021-08

Locations

CN(1)