NCT04450433

Brief Summary

Research on metabolites in patients with aortic dissection, with a view to finding products with high or low metabolism in patients with aortic dissection, looking for metabolic factors related to the onset of aortic dissection, and further verifying the role of metabolic factors in disease through functional verification The role of formation, and ultimately explore the early screening of potential aortic dissection patients

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2019

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 24, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 29, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2020

Completed
Last Updated

June 29, 2020

Status Verified

June 1, 2020

Enrollment Period

9 months

First QC Date

June 24, 2020

Last Update Submit

June 24, 2020

Conditions

Aortic Dissection

Outcome Measures

Primary Outcomes (1)

  • Differential expression of metabolites in two groups of patients

    Differential expression of metabolites in the two groups of patients, looking for metabolic factors related to the incidence of aortic dissection, and further verifying the function of metabolites through functional methods, with a view to finding high-risk metabolic factors for patients with aortic dissection

    2019-11----2021.01

Study Arms (3)

Baseline table of patients

Diagnostic Test: aortic dissection and healthy people

Differential metabolites of two groups of control patients

Diagnostic Test: aortic dissection and healthy people

Functional verification of differential metabolites

Diagnostic Test: aortic dissection and healthy people

Interventions

aortic dissection and healthy peopleDIAGNOSTIC_TEST

Differential expression of metabolites in patients with aortic dissection and healthy people

Baseline table of patientsDifferential metabolites of two groups of control patientsFunctional verification of differential metabolites

Eligibility Criteria

Age30 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

30 patients with aortic dissection and 15 healthy people

You may qualify if:

  • patients with Aortic dissection

You may not qualify if:

  • Sepsis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shenzhen People's Hospital

Shenzhen, Guangdong, 518020, China

RECRUITING

MeSH Terms

Conditions

Aortic Dissection

Condition Hierarchy (Ancestors)

Dissection, Blood VesselAneurysmVascular DiseasesCardiovascular DiseasesAcute Aortic SyndromeAortic Diseases

Central Study Contacts

Huadong Liu

CONTACT

13724397998lhd2578@163.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 24, 2020

First Posted

June 29, 2020

Study Start

November 1, 2019

Primary Completion

July 30, 2020

Study Completion

October 30, 2020

Last Updated

June 29, 2020

Record last verified: 2020-06

Locations

CN(1)