Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries
1 other identifier
observational
78,888
1 country
1
Brief Summary
Preoperative serum cholesterol level may influence occurrence of postoperative acute kidney injury of cardiac surgeries. However, the effect of Preoperative serum cholesterol level for non cardiac surgery remains unknown. This study aimed to explore the effect in non-cardiac surgical population.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2019
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 16, 2019
CompletedFirst Posted
Study publicly available on registry
May 17, 2019
CompletedStudy Start
First participant enrolled
May 17, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 5, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
June 6, 2019
CompletedJuly 9, 2019
July 1, 2019
19 days
May 16, 2019
July 8, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
post-operative acute kidney injury within 30 days in the hospital
It was defined by patient's postoperative serum creatine increase no less than 26.5 μmol/l within 48 hours, or 1.5 times from baseline within the 7 days after surgery or initializing blood dialysis.
30 days postoperatively in hospital
Eligibility Criteria
adults (age ≥ 18 years old) who underwent elective non-cardiac surgery from January 1, 2012, to December 31, 2017.
You may qualify if:
- adults elective non-cardiac surgery
You may not qualify if:
- cardiac surgeries kidney surgeries obstetric surgeries local infiltration anesthesia perioperative data missing
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
First hospital Peking University
Beijing, Beijing Municipality, 100034, China
Related Publications (1)
Zhou Y, Yang HY, Zhang HL, Zhu XJ. High-density lipoprotein cholesterol concentration and acute kidney injury after noncardiac surgery. BMC Nephrol. 2020 Apr 25;21(1):149. doi: 10.1186/s12882-020-01808-7.
PMID: 32334566DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
May 16, 2019
First Posted
May 17, 2019
Study Start
May 17, 2019
Primary Completion
June 5, 2019
Study Completion
June 6, 2019
Last Updated
July 9, 2019
Record last verified: 2019-07