Resistance Training Effects on Muscle Morphological, Mechanical and Contractile Properties

NCT04845295 | Completed

• 1 other identifier: 2316/19-2
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the research project is to investigate the influence of resistance-training prescription (repetition duration, time under tension and training volume) and sex have on morpho-functional adaptations of upper and lower-body skeletal muscles. Twenty-four male and female university students were randomly assigned to one of two experimental groups, based on the repetition duration : "fast" group (with 1 second for eccentric and concentric phase) and "slow" group with prolonged duration of eccentric contraction (4 seconds for eccentric and 1 second concentric phase). At baseline and final measurement, cross-section area, one-repetition maximum and tensiomyography parameters (contraction time - Tc and radial displacement - Dm) of elbow flexors (biceps brachii) and knee extensors (4 quadriceps muscles) were evaluated.

Conditions

Hypertrophy; Contraction

Outcome Measures

Primary Outcomes (3)

• muscle hypertrophy

  cross-section area assessment

  7 weeks

• muscle strength changes

  one-repetition maximum assessment

  7 weeks

• contractile properties changes

  TMG assessment

  7 weeks

Study Arms (2)

Fast Tempo

EXPERIMENTAL

Performed training intervention with a tempo of 1 second for eccentric and 1 second for concentric phase

Other: resistance training

Slow Tempo

EXPERIMENTAL

Performed training intervention with a tempo of 4 seconds for eccentric and 1 second for concentric phase

Other: resistance training

Interventions

resistance training OTHER

Both experimental groups performed two exercises to target elbow flexor and knee extensor muscles: biceps curl on a Scott bench and parallel barbell squat, respectively. All sessions were performed at the same time (13-15 h), with a minimum 48 h rest between sessions on the same days during the week. For both groups, the intensity of load (1RM%) and number of sets were as follows: in the first three weeks the subjects exercises with ̴ 60% of 1RM in 3 sets, while during the next four weeks the load was set at ̴ 70% of 1RM in 4 sets. All repetitions were performed until muscular failure. The pause between sets was 2 minutes.

Fast Tempo; Slow Tempo

Eligibility Criteria

• Age: 20 Years - 35 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• without resistance training participation in past 8 months

You may not qualify if:

• history of upper or lower body musculoskeletal injuries

Sponsors & Collaborators

• University of Belgrade: lead

Study Sites (1)

Faculty of Sport and Physical Education

Belgrade, 11000, Serbia

Location

Related Publications (6)

• Hackett DA, Davies TB, Orr R, Kuang K, Halaki M. Effect of movement velocity during resistance training on muscle-specific hypertrophy: A systematic review. Eur J Sport Sci. 2018 May;18(4):473-482. doi: 10.1080/17461391.2018.1434563. Epub 2018 Feb 12.

  PMID: 29431597 BACKGROUND

• Schoenfeld BJ. The mechanisms of muscle hypertrophy and their application to resistance training. J Strength Cond Res. 2010 Oct;24(10):2857-72. doi: 10.1519/JSC.0b013e3181e840f3.

  PMID: 20847704 BACKGROUND

• Davies TB, Kuang K, Orr R, Halaki M, Hackett D. Effect of Movement Velocity During Resistance Training on Dynamic Muscular Strength: A Systematic Review and Meta-Analysis. Sports Med. 2017 Aug;47(8):1603-1617. doi: 10.1007/s40279-017-0676-4.

  PMID: 28105573 BACKGROUND

• Pisot R, Narici MV, Simunic B, De Boer M, Seynnes O, Jurdana M, Biolo G, Mekjavic IB. Whole muscle contractile parameters and thickness loss during 35-day bed rest. Eur J Appl Physiol. 2008 Sep;104(2):409-14. doi: 10.1007/s00421-008-0698-6. Epub 2008 Feb 23.

  PMID: 18297302 BACKGROUND

• Pryor RR, Sforzo GA, King DL. Optimizing power output by varying repetition tempo. J Strength Cond Res. 2011 Nov;25(11):3029-34. doi: 10.1519/JSC.0b013e31820f50cb.

  PMID: 21881531 BACKGROUND

• Kojic F, Mandic D, Ilic V. Resistance training induces similar adaptations of upper and lower-body muscles between sexes. Sci Rep. 2021 Dec 6;11(1):23449. doi: 10.1038/s41598-021-02867-y.

  PMID: 34873221 DERIVED

MeSH Terms

Conditions

Hypertrophy

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Vladimir Ilic

  Faculty of Sport and Physical Education, University of Belgrade

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: April 10, 2021
• First Posted: April 14, 2021
• Study Start: March 1, 2019
• Primary Completion: May 7, 2019
• Study Completion: May 7, 2019
• Last Updated: April 19, 2021

Record last verified: 2021-04

Locations

SE (1)