NCT03196856

Brief Summary

This study will analyze the effects of Greek yogurt consumption and an 12 week exercise intervention on muscle size, body composition and bone health in untrained, university-aged males.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 14, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 23, 2017

Completed
8 days until next milestone

Study Start

First participant enrolled

July 1, 2017

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2018

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2019

Completed
Last Updated

September 17, 2019

Status Verified

September 1, 2019

Enrollment Period

1.2 years

First QC Date

June 14, 2017

Last Update Submit

September 15, 2019

Conditions

UntrainedHealthy

Keywords

Greek YogurtMuscle SizeBone HealthBody CompositionExercise

Outcome Measures

Primary Outcomes (3)

  • Muscular Strength

    1 Repetition Maximum of bench press, seated row, quad extension and hamstring curl

    Change from Baseline to 12 weeks

  • Muscle Size

    Muscle Size determined by ultrasound at various sites.

    Change from Baseline to 12 weeks

  • Body Composition

    Body Fat % measured via BodPod and BodyMetrix

    Change from Baseline to 12 weeks

Secondary Outcomes (2)

  • Bone cell activity

    Change from Baseline to 12 weeks

  • Vertical Jump Height

    Change from Baseline to 12 weeks

Study Arms (2)

Yogurt Group

EXPERIMENTAL

Group will be consuming 200g of Greek Yogurt (Plain, 0%) 3 times daily for 12 weeks

Behavioral: Resistance and Plyometric ExerciseDietary Supplement: Greek Yogurt (0% Plain)

Study Designed Supplement Group

PLACEBO COMPARATOR

Group will consume an isoenergetic, protein void, maltodextrin-based placebo supplement during the same time points for 12 weeks as well. The Placebo contain maltodextrin and pudding powder to mimic the consistency of Greek yogurt.

Behavioral: Resistance and Plyometric ExerciseDietary Supplement: Placebo - Study Designed Supplement

Interventions

Resistance and Plyometric ExerciseBEHAVIORAL

12 weeks of Resistance (twice weekly) and Plyometric (once weekly) training

Study Designed Supplement GroupYogurt Group
Greek Yogurt (0% Plain)DIETARY_SUPPLEMENT

200g 3x/day for 12 weeks.

Yogurt Group
Placebo - Study Designed SupplementDIETARY_SUPPLEMENT

Iso-energetic to yogurt. 3x/day for 12 weeks.

Study Designed Supplement Group

Eligibility Criteria

Age18 Years - 25 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Male
  • Age 18-25 years
  • Normal BMI (18.5-24.9) kg/m2
  • Have not participated in a resistance training program (of resistance exercise at least 2x/week or more) in the last 6 months
  • Healthy and not taking any medication affecting muscle or bone
  • Not supplementing with vitamins/ minerals or protein
  • Speak and understand English
  • No dairy allergy or lactose intolerance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Brock University

St. Catharines, Ontario, L2S3A1, Canada

Location

Related Publications (1)

  • Bridge A, Brown J, Snider H, Nasato M, Ward WE, Roy BD, Josse AR. Greek Yogurt and 12 Weeks of Exercise Training on Strength, Muscle Thickness and Body Composition in Lean, Untrained, University-Aged Males. Front Nutr. 2019 Apr 30;6:55. doi: 10.3389/fnut.2019.00055. eCollection 2019.

    PMID: 31114790RESULT

Related Links

MeSH Terms

Conditions

Motor Activity

Interventions

Plyometric Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Andrea Josse, PhD

    Brock University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Participants will be randomly selected to the yogurt group or a placebo group. Although participants within the yogurt group will be aware that they are consuming yogurt, the placebo group will not be aware of the contents of the placebo supplement.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized Controlled Trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

June 14, 2017

First Posted

June 23, 2017

Study Start

July 1, 2017

Primary Completion

August 30, 2018

Study Completion

May 30, 2019

Last Updated

September 17, 2019

Record last verified: 2019-09

Locations

CA(1)