NCT01666561

Brief Summary

To test the hypothesis that two 40 gm serving of Oat-based breakfast cereals compared to an equicaloric amount of a ready-to-eat Oat-based breakfast cereal will give greater satiety over the 4 hour period following breakfast.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2012

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

August 14, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 16, 2012

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2013

Completed
Last Updated

December 18, 2015

Status Verified

December 1, 2015

Enrollment Period

11 months

First QC Date

August 14, 2012

Last Update Submit

December 17, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Satiety Impact

    Breakfast containing of oat-based breakfast cereal will cause people to feel more satiated compared to a breakfast containing of ready-to-eat oat-based breakfast cereal. Appetite and satiety will be measured with a Visual Analog Scale.

    up to day 3

Study Arms (3)

Breakfast Test Cereal 1, Oat based

EXPERIMENTAL

Test cereal 1, Oat based breakfast cereal- you will be randomly presented with a breakfast consisting of either: Oat-based breakfast cereal with lactose-free, fat-free milk to drink or ready-to-eat cereal in lactose-free, fat -free milk with water to drink. Then you will complete a visual analog scale at 30, 60, 120. 180, and 240 minutes following the start of breakfast meal.

Other: Breakfast Test Cereal 1, Oat basedOther: Breakfast Test Cereal 2, Oat-basedOther: Ready-to-eat cereal

Breakfast Test Cereal 2, Oat-based

EXPERIMENTAL

Test Cereal 2, Oat-based breakfast cereal. You will be randomly presented with a breakfast consisting of either: Oat-based breakfast cereal with lactose-free, fat-free milk to drink or ready-to-eat oat brand cereal in lactose-free, fat -free milk with water to drink. Then you will complete a visual analog scale at 30, 60, 120. 180, and 240 minutes following the start of breakfast meal.

Other: Breakfast Test Cereal 1, Oat basedOther: Breakfast Test Cereal 2, Oat-basedOther: Ready-to-eat cereal

Ready-to-eat cereal

EXPERIMENTAL

Ready-to-eat cereal, Oat based breakfast cereal- you will be randomly presented with a breakfast consisting of either: one Oat-based breakfast cereal with lactose-free, fat-free milk to drink or ready-to-eat cereal in lactose-free, fat -free milk with water to drink. Then you will complete a visual analog scale at 30, 60, 120. 180, and 240 minutes following the start of breakfast meal.

Other: Breakfast Test Cereal 1, Oat basedOther: Breakfast Test Cereal 2, Oat-basedOther: Ready-to-eat cereal

Interventions

The study design is a crossover trial with each subject receiving one of the cereals in each of three visits separated by at least a week will be enrolled to investigate the satiety impact of three breakfast cereals: (a) one serving of oat based breakfast cereal 1.

Breakfast Test Cereal 1, Oat basedBreakfast Test Cereal 2, Oat-basedReady-to-eat cereal

The study design is a crossover trial with each subject receiving one of the cereals in each of three visits separated by at least a week will be enrolled to investigate the satiety impact of three breakfast cereals: (b) an equicaloric amount of Oat based breakfast cereal 2.

Breakfast Test Cereal 1, Oat basedBreakfast Test Cereal 2, Oat-basedReady-to-eat cereal

The study design is a crossover trial with each subject receiving one of the cereals in each of three visits separated by at least a week will be enrolled to investigate the satiety impact of three breakfast cereals: (c) an equicaloric amount of the ready-to-eat cold cereal.

Breakfast Test Cereal 1, Oat basedBreakfast Test Cereal 2, Oat-basedReady-to-eat cereal

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age or older and are healthy.
  • Taking no regular medications other than birth control or hormone replacement therapy.
  • Are willing to use an effective method of birth control if you are capable of bearing children. Acceptable methods include abstinence, barrier methods, intrauterine devices, and hormonal methods of contraception.

You may not qualify if:

  • Are a woman who is pregnant or nursing a baby.
  • Have gained or lost 8.8 pounds or more in the last 3 months.
  • Have diabetes or a fasting blood sugar over 126 mg/dL.
  • Have a score of 14 or greater on the restraint scale of the 3-factor eating questionnaire (a questionnaire which will be given to you by the study staff).
  • Are allergic to oats, lactose-free milk, Honey Nut Cheerios or oatmeal.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 14, 2012

First Posted

August 16, 2012

Study Start

August 1, 2012

Primary Completion

July 1, 2013

Study Completion

July 1, 2013

Last Updated

December 18, 2015

Record last verified: 2015-12

Locations